Journal
PRIMARY CARE
Volume 47, Issue 4, Pages 645-659Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.pop.2020.08.004
Keywords
Diabetic kidney disease; Diabetic nephropathy; Chronic kidney disease; Albuminuria
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Diabetic kidney disease (DKD) is the most common cause of chronic kidney disease in the United States. Approximately 30% to 40% of individuals with diabetes mellitus develop DKD, and the presence of DKD significantly elevates the risk for morbidity and mortality. Understanding of DKD has grown in recent years. This review describes the pathogenesis of DKD and expands on evidence-based strategies for DKD management, integrating traditional approaches for hyperglycemia, hypertension, and albuminuria management with emerging therapeutic options. Given the public health burden of DKD, it is essential to prioritize prevention, recognition, and management of DKD in the primary care setting.
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