Nail Psoriasis: A Review of Treatment Options

Apremilast, an oral phosphodiesterase 4 inhibitor, in patients with difficult-to-treat nail and scalp psoriasis: Results of 2 phase III randomized, controlled trials (ESTEEM 1 and ESTEEM 2)

(2016) Phoebe Rich et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Efficacy and safety of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with moderate-to-severe plaque psoriasis over 52 weeks: a phase III, randomized controlled trial (ESTEEM 2)

(2015) C. Paul et al.   BRITISH JOURNAL OF DERMATOLOGY

Apremilast: A Review in Psoriasis and Psoriatic Arthritis

(2015) Emma D. Deeks   DRUGS

Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: Results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1)

(2015) Kim Papp et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Improvement of scalp and nail lesions with ixekizumab in a phase 2 trial in patients with chronic plaque psoriasis

(2015) R.G. Langley et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Original paper Autoimmunogenicity during anti-TNF therapy in patients with psoriasis and psoriatic arthritis

(2015) Magdalena M. Pirowska et al.   Postepy Dermatologii i Alergologii

A Chinese Herb, Indigo Naturalis, Extracted in Oil (Lindioil) Used Topically to Treat Psoriatic Nails

(2015) Yin-Ku Lin et al.   JAMA Dermatology

Nail involvement as a predictor of concomitant psoriatic arthritis in patients with psoriasis

(2014) A. Langenbruch et al.   BRITISH JOURNAL OF DERMATOLOGY

The Impact of Fingernail Psoriasis on Patients' Health-Related and Disease-Specific Quality of Life

(2014) Haike M.J. van der Velden et al.   DERMATOLOGY

Anthralin/dithranol in dermatology

(2014) Virendra N. Sehgal et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Acitretin in psoriasis: an evolving scenario

(2014) Sunil Dogra et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Scoring nail psoriasis

(2014) Karlijn M.G. Klaassen et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Secukinumab improves hand, foot and nail lesions in moderate-to-severe plaque psoriasis: subanalysis of a randomized, double-blind, placebo-controlled, regimen-finding phase 2 trial

(2014) C. Paul et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Adalimumab for the treatment of moderate to severe psoriasis: subanalysis of effects on scalp and nails in the BELIEVE study

(2014) D. Thaçi et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Nail Psoriasis, the unknown burden of disease

(2014) K.M.G. Klaassen et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Efficacy and safety of Indigo naturalis extract in oil (Lindioil) in treating nail psoriasis: A randomized, observer-blind, vehicle-controlled trial

(2014) Yin-Ku Lin et al.   PHYTOMEDICINE

Effect of certolizumab pegol on signs and symptoms in patients with psoriatic arthritis: 24-week results of a Phase 3 double-blind randomised placebo-controlled study (RAPID-PsA)

(2013) P J Mease et al.   ANNALS OF THE RHEUMATIC DISEASES

Infliximab in Psoriasis and Psoriatic Arthritis

(2013) Marina Papoutsaki et al.   BIODRUGS

Nail psoriasis: a questionnaire-based survey

(2013) K.M.G. Klaassen et al.   BRITISH JOURNAL OF DERMATOLOGY

Ustekinumab improves nail disease in patients with moderate-to-severe psoriasis: results from PHOENIX 1

(2013) P. Rich et al.   BRITISH JOURNAL OF DERMATOLOGY

Nail Assessment in Psoriasis and Psoriatic Arthritis (NAPPA): development and validation of a tool for assessment of nail psoriasis outcomes

(2013) M. Augustin et al.   BRITISH JOURNAL OF DERMATOLOGY

Treatment of severe nail psoriasis with acitretin: an impressive therapeutic result

(2013) F. Ricceri et al.   Dermatologic Therapy

Onychomycosis in patients of nail psoriasis on biologic therapy: a randomized, prospective open label study comparing Etanercept, Infliximab and Adalimumab

(2013) Nawaf Al-Mutairi et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

IL-17 targeted therapies for psoriasis

(2013) Andrea Chiricozzi et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Ustekinumab for the treatment of nail psoriasis in heavily treated psoriatic patients

(2013) Magalys Vitiello et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Treatment of nail psoriasis with tumor necrosis factor-alpha blocker agents: An open-label, unblinded, comparative study

(2013) Ibrahim Ozmen et al.   JOURNAL OF DERMATOLOGY

Efficacy of adalimumab across subgroups of patients with moderate-to-severe chronic plaque psoriasis of the hands and/or feet: post hoc analysis of REACH

(2013) Y. Poulin et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

The prevalence of onychomycosis in psoriatic patients: a systematic review

(2013) K.M.G. Klaassen et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Efficacy of pulsed dye laser plus topical tazarotene versus topical tazarotene alone in psoriatic nail disease: A single-blind, intrapatient left-to-right controlled study

(2013) Yu-Chen Huang et al.   LASERS IN SURGERY AND MEDICINE

Nail psoriasis treated with pulse dye laser

(2013) Ahmed Al Mutairi et al.   INDIAN JOURNAL OF DERMATOLOGY

Comparison of nail lacquer clobetasol efficacy at 0,05%, 1% and 8% in nail psoriasis treatment: prospective, controlled and randomized pilot study

(2012) Robertha Carvalho Nakamura et al.   ANAIS BRASILEIROS DE DERMATOLOGIA

Golimumab in psoriatic arthritis: One-year clinical efficacy, radiographic, and safety results from a phase III, randomized, placebo-controlled trial

(2012) Arthur Kavanaugh et al.   ARTHRITIS AND RHEUMATISM

Secukinumab induction and maintenance therapy in moderate-to-severe plaque psoriasis: a randomised, double-blind, placebo-controlled, phase II regimen-finding study

(2012) P. Rich et al.   BRITISH JOURNAL OF DERMATOLOGY

Brodalumab and ixekizumab, anti-interleukin-17-receptor antibodies for psoriasis: a critical appraisal

(2012) Ph. I. Spuls et al.   BRITISH JOURNAL OF DERMATOLOGY

Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled phase II dose-ranging study

(2012) K.A. Papp et al.   BRITISH JOURNAL OF DERMATOLOGY

A 24-week randomized clinical trial investigating the efficacy and safety of two doses of etanercept in nail psoriasis

(2012) J.P. Ortonne et al.   BRITISH JOURNAL OF DERMATOLOGY

Marked improvement in nail psoriasis during treatment with etanercept

(2012) MERCEDES GÓMEZ VÁZQUEZ et al.   Dermatologic Therapy

TNF-α antagonists and nail psoriasis: an open, 24-week, prospective cohort study in adult patients with psoriasis

(2012) Rosita Saraceno et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The effect of different pulse durations in the treatment of nail psoriasis with 595-nm pulsed dye laser: A randomized, double-blind, intrapatient left-to-right study

(2012) Chanitwan Treewittayapoom et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Re-evaluation of the risk for major adverse cardiovascular events in patients treated with anti-IL-12/23 biological agents for chronic plaque psoriasis: a meta-analysis of randomized controlled trials

(2012) T. Tzellos et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Tacrolimus 0.1% ointment in nail psoriasis: a randomized controlled open-label study

(2012) C. De Simone et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Psoriasis

(2012)   NEW ENGLAND JOURNAL OF MEDICINE

Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis

(2012) Craig Leonardi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Leflunomide in psoriatic arthritis: Results from a large European prospective observational study

(2012) Frank Behrens et al.   ARTHRITIS CARE & RESEARCH

Treatment of Psoriatic Nails with Indigo Naturalis Oil Extract: A Non-Controlled Pilot Study

(2011) Yin-Ku Lin et al.   DERMATOLOGY

Efficacy of Ustekinumab in Nail Psoriasis and Improvement in Nail-Associated Quality of Life in a Population Treated with Ustekinumab for Cutaneous Psoriasis: An Open Prospective Unblinded Study

(2011) D. Rigopoulos et al.   DERMATOLOGY

Nail Psoriasis Successfully Treated with Intralesional Methotrexate: Case Report

(2011) Hayriye Sarıcaoglu et al.   DERMATOLOGY

Treatment of severe nail psoriasis with etanercept

(2011) JoanaDias Coelho et al.   Indian Journal of Dermatology Venereology & Leprology

Efficacy of adalimumab in the treatment of psoriasis: A retrospective study of 15 patients in daily practice

(2011) Joaquín Sola-Ortigosa et al.   JOURNAL OF DERMATOLOGICAL TREATMENT

Ustekinumab in nail psoriasis: an open-label, uncontrolled, nonrandomized study

(2011) Aikaterini Patsatsi et al.   JOURNAL OF DERMATOLOGICAL TREATMENT

Anti-TNF agents and nail psoriasis: a single-center, retrospective, comparative study

(2011) Aikaterini Kyriakou et al.   JOURNAL OF DERMATOLOGICAL TREATMENT

Dramatic impact of a Psoriasis Area and Severity Index 90 response on the quality of life in patients with psoriasis: An analysis of Japanese clinical trials of infliximab

(2011) Hideshi TORII et al.   JOURNAL OF DERMATOLOGY

Efficacy and safety of ustekinumab in Japanese patients with moderate-to-severe plaque-type psoriasis: Long-term results from a phase 2/3 clinical trial

(2011) Atsuyuki IGARASHI et al.   JOURNAL OF DERMATOLOGY

Adalimumab or Cyclosporine as Monotherapy and in Combination in Severe Psoriatic Arthritis: Results from a Prospective 12-month Nonrandomized Unblinded Clinical Trial

(2011) G. N. KARANIKOLAS et al.   JOURNAL OF RHEUMATOLOGY

A 52-Week Trial Comparing Briakinumab with Methotrexate in Patients with Psoriasis

(2011) Kristian Reich et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ustekinumab for Rapid Treatment of Nail Psoriasis

(2010) Efstathios Rallis et al.   ARCHIVES OF DERMATOLOGY

UV-A and UV-B Penetration of Normal Human Cadaveric Fingernail Plate

(2010) Dana K. Stern et al.   ARCHIVES OF DERMATOLOGY

Adalimumab for Treatment of Moderate to Severe Chronic Plaque Psoriasis of the Hands and Feet

(2010) Craig Leonardi et al.   ARCHIVES OF DERMATOLOGY

A phase IIIb, multicentre, randomized, double-blind, vehicle-controlled study of the efficacy and safety of adalimumab with and without calcipotriol/betamethasone topical treatment in patients with moderate to severe psoriasis: the BELIEVE study

(2010) D. Thaçi et al.   BRITISH JOURNAL OF DERMATOLOGY

Pulsed Dye Laser in the Treatment of Nail Psoriasis

(2010) YASEMIN ORAM et al.   DERMATOLOGIC SURGERY

Skin and Nail Responses after 1 Year of Infliximab Therapy in Patients with Moderate-to-Severe Psoriasis: A Retrospective Analysis of the EXPRESS Trial

(2010) Kristian Reich et al.   DERMATOLOGY

Evaluation of nail disease in psoriatic arthritis by using a modified nail psoriasis severity score index

(2010) Hideki Maejima et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Infliximab monotherapy in Japanese patients with moderate-to-severe plaque psoriasis and psoriatic arthritis. A randomized, double-blind, placebo-controlled multicenter trial

(2010) Hideshi Torii et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Long-term study of infliximab in Japanese patients with plaque psoriasis, psoriatic arthritis, pustular psoriasis and psoriatic erythroderma

(2010) Hideshi TORII et al.   JOURNAL OF DERMATOLOGY

Nail psoriasis: a retrospective study on the effectiveness of systemic treatments (classical and biological therapy)

(2010) M Sánchez-Regaña et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Evaluation of the efficacy of methotrexate and cyclosporine therapies on psoriatic nails: a one-blind, randomized study

(2010) M. Gümüşel et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Infliximab efficacy in nail psoriasis. A retrospective study in 48 patients

(2010) C Fabroni et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Effectiveness and safety of adalimumab in patients with ankylosing spondylitis or psoriatic arthritis and history of anti-tumor necrosis factor therapy

(2010) Martin Rudwaleit et al.   ARTHRITIS RESEARCH & THERAPY

Effectiveness of adalimumab in treating patients with active psoriatic arthritis and predictors of good clinical responses for arthritis, skin and nail lesions

(2009) F Van den Bosch et al.   ANNALS OF THE RHEUMATIC DISEASES

Evaluation of the Efficacy of Acitretin Therapy for Nail Psoriasis

(2009) Antonella Tosti et al.   ARCHIVES OF DERMATOLOGY

Golimumab, a new human tumor necrosis factor α antibody, administered every four weeks as a subcutaneous injection in psoriatic arthritis: Twenty-four-week efficacy and safety results of a randomized, placebo-controlled study

(2009) Arthur Kavanaugh et al.   ARTHRITIS AND RHEUMATISM

Marked Improvement in Nail Psoriasis during Treatment with Adalimumab

(2009) N. Irla et al.   DERMATOLOGY

Treatment of Nail Psoriasis with a Two-Compound Formulation of Calcipotriol plus Betamethasone Dipropionate Ointment

(2009) D. Rigopoulos et al.   DERMATOLOGY

Tacalcitol ointment for the treatment of nail psoriasis

(2009) Gemma Márquez Balbás et al.   JOURNAL OF DERMATOLOGICAL TREATMENT

Pulsed dye laser vs. photodynamic therapy in the treatment of refractory nail psoriasis: a comparative pilot study

(2009) M Fernández-Guarino et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Sustained improvement in joint pain and nail symptoms with etanercept therapy in patients with moderate-to-severe psoriasis

(2009) TA Luger et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Treatment of nail psoriasis with adalimumab: an open label unblinded study

(2009) D Rigopoulos et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis

(2009) Rafael de Cid et al.   NATURE GENETICS

Psoriasis

(2009) Frank O. Nestle et al.   NEW ENGLAND JOURNAL OF MEDICINE

β-Defensin-2 Protein Is a Serum Biomarker for Disease Activity in Psoriasis and Reaches Biologically Relevant Concentrations in Lesional Skin

(2009) Patrick A. M. Jansen et al.   PLoS One

Management of Psoriatic Nail Disease

(2009) David de Berker   SEMINARS IN CUTANEOUS MEDICINE AND SURGERY

Evaluation of the efficacy and safety of infliximab on psoriatic nails: an unblinded, nonrandomized, open-label study

(2008) D. Rigopoulos et al.   BRITISH JOURNAL OF DERMATOLOGY

Severe recalcitrant nail psoriasis responding dramatically to infliximab: report of two patients

(2008) W. Hussain et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Nail psoriasis: a combined treatment with 8 clobetasol nail lacquer and tacalcitol ointment

(2008) M Snchez Regaa et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Baseline nail disease in patients with moderate to severe psoriasis and response to treatment with infliximab during 1 year

(2007) Phoebe Rich et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY