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Title
CYP2J2 – regulation, function and polymorphism
Authors
Keywords
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Journal
DRUG METABOLISM REVIEWS
Volume 48, Issue 3, Pages 351-368
Publisher
Informa UK Limited
Online
2016-06-10
DOI
10.1080/03602532.2016.1188938
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- (2015) Guangzhi Chen et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
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- (2014) Céline Narjoz et al. PLoS One
- Time-dependent expression of cytochrome p450 epoxygenases during human prenatal development
- (2014) Katerina Cizkova et al. Organogenesis
- Predictive Value of CYP3A and ABCB1 Phenotyping Probes for the Pharmacokinetics of Sunitinib: the ClearSun Study
- (2013) Jacqueline S. L. Kloth et al. CLINICAL PHARMACOKINETICS
- A Common Polymorphism G-50T in Cytochrome P450 2J2 Gene Is Associated with Increased Risk of Essential Hypertension in a Russian Population
- (2013) Alexey V. Polonikov et al. DISEASE MARKERS
- Cardiac-Specific Overexpression of CYP2J2 Attenuates Diabetic Cardiomyopathy in Male Streptozotocin-Induced Diabetic Mice
- (2013) Ben Ma et al. ENDOCRINOLOGY
- Let-7 in Cardiovascular Diseases, Heart Development and Cardiovascular Differentiation from Stem Cells
- (2013) Mei-Hua Bao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2013) Jonas Bystrom et al. PLoS One
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- (2013) G. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of cytochrome P450s involved in the metabolism of arachidonic acid in human platelets
- (2013) Yazun B. Jarrar et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Impact of Soluble Epoxide Hydrolase and Epoxyeicosanoids on Human Health
- (2012) Christophe Morisseau et al. Annual Review of Pharmacology and Toxicology
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- (2012) Sussan Ghassabian et al. BIOCHEMICAL PHARMACOLOGY
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- (2012) Holly K. Bryan et al. BIOCHEMICAL PHARMACOLOGY
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- (2012) Hongmei Xu et al. CURRENT DRUG METABOLISM
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- (2012) Abdullah Alghasham et al. Genetic Testing and Molecular Biomarkers
- Expression of vitamin D-metabolizing enzymes in human adipose tissue—the effect of obesity and diet-induced weight loss
- (2012) L Wamberg et al. INTERNATIONAL JOURNAL OF OBESITY
- Role of PI3Kα and sarcolemmal ATP-sensitive potassium channels in epoxyeicosatrienoic acid mediated cardioprotection
- (2012) Sri N. Batchu et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
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- (2010) William B. Campbell et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- PharmGKB summary
- (2010) Dorit S. Berlin et al. Pharmacogenetics and Genomics
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- (2010) Beshay N.M. Zordoky et al. PHARMACOLOGY & THERAPEUTICS
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- (2009) Julie Leclerc et al. BIOCHIMIE
- Xenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral Function
- (2009) F. Dutheil et al. DRUG METABOLISM AND DISPOSITION
- Identification of Novel Substrates for Human Cytochrome P450 2J2
- (2009) C. A. Lee et al. DRUG METABOLISM AND DISPOSITION
- Eicosapentaenoic acid increases cytochrome P-450 2J2 gene expression and epoxyeicosatrienoic acid production via peroxisome proliferator-activated receptor γ in endothelial cells
- (2009) Dahai Wang et al. Journal of Cardiology
- 14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) Surrogates Containing Epoxide Bioisosteres: Influence upon Vascular Relaxation and Soluble Epoxide Hydrolase Inhibition
- (2009) J. R. Falck et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2009) D. Katragadda et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
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- (2009) Alberto Mantovani NATURE
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- (2008) Maude Fer et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
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- (2008) John D. Imig et al. MICROCIRCULATION
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- (2008) Helen E. Smith et al. Pharmacogenetics and Genomics
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- (2008) Kristin D. Marciante et al. Pharmacogenetics and Genomics
- Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population
- (2008) Laxi Zhang et al. Pharmacogenetics and Genomics
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- (2008) T. Boutros et al. PHARMACOLOGICAL REVIEWS
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