Luteolin suppresses androgen receptor-positive triple-negative breast cancer cell proliferation and metastasis by epigenetic regulation of MMP9 expression via the AKT/mTOR signaling pathway

A potential breast cancer dual therapy using phytochemicals-loaded nanoscale penetration enhancing vesicles: A double impact weapon in the arsenal

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Androgen receptor in triple negative breast cancer: A potential target for the targetless subtype

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Mammalian target of rapamycin complex 2 (mTORC2) controls glycolytic gene expression by regulating Histone H3 Lysine 56 acetylation

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Rhizoma Amorphophalli inhibits TNBC cell proliferation, migration, invasion and metastasis through the PI3K/Akt/mTOR pathway

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TRIM59 facilitates the proliferation of colorectal cancer and promotes metastasis via the PI3K/AKT pathway

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The Wnt/β-catenin and PI3K/Akt signaling pathways promote EMT in gastric cancer by epigenetic regulation via H3 lysine 27 acetylation

(2017) Yue Song et al.   TUMOR BIOLOGY

PI3K/AKT-mediated upregulation of WDR5 promotes colorectal cancer metastasis by directly targeting ZNF407

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Inhibition of histone deacetylases in cancer therapy: lessons from leukaemia

(2016) Elena Ceccacci et al.   BRITISH JOURNAL OF CANCER

Targeting the androgen receptor in triple-negative breast cancer

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Luteolin suppresses the metastasis of triple-negative breast cancer by reversing epithelial-to-mesenchymal transition via downregulation of β-catenin expression

(2016) Dan Lin et al.   ONCOLOGY REPORTS

K63-polyubiquitinated HAUSP deubiquitinates HIF-1α and dictates H3K56 acetylation promoting hypoxia-induced tumour progression

(2016) Han-Tsang Wu et al.   Nature Communications

HDAC5, a potential therapeutic target and prognostic biomarker, promotes proliferation, invasion and migration in human breast cancer

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Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection

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Multiple Molecular Subtypes of Triple-Negative Breast Cancer Critically Rely on Androgen Receptor and Respond to Enzalutamide In Vivo

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Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells

(2015) Devon A. Lawson et al.   NATURE

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(2015) Yaghoub Safdari et al.   PHARMACOLOGICAL RESEARCH

Targeting the Androgen Receptor in Breast Cancer

(2015) KeeMing Chia et al.   Current Oncology Reports

Luteolin inhibits progestin-dependent angiogenesis, stem cell-like characteristics, and growth of human breast cancer xenografts

(2015) Matthew T. Cook et al.   SpringerPlus

Effects of Flavonoids from Potamogeton crispus L. on Proliferation, Migration, and Invasion of Human Ovarian Cancer Cells

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(2014) Mohammed A. Aleskandarany et al.   BREAST CANCER RESEARCH AND TREATMENT

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Androgen Receptor Status Is a Prognostic Marker in Non-Basal Triple Negative Breast Cancers and Determines Novel Therapeutic Options

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Differential Response to Neoadjuvant Chemotherapy Among 7 Triple-Negative Breast Cancer Molecular Subtypes

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Histone Deacetylase (HDAC) 10 Suppresses Cervical Cancer Metastasis through Inhibition of Matrix Metalloproteinase (MMP) 2 and 9 Expression

(2013) Chenlin Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Luteolin suppresses UVB-induced photoageing by targeting JNK1 and p90RSK2

(2013) Sung H. Lim et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Loss of androgen receptor expression predicts early recurrence in triple-negative and basal-like breast cancer

(2013) Aye Aye Thike et al.   MODERN PATHOLOGY

Expression of androgen receptors in triple negative breast carcinomas

(2012) Ivana Mrklić et al.   ACTA HISTOCHEMICA

Epigenetic regulation of mmp-9 gene expression

(2012) Marilyne Labrie et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Pharmacokinetic study of luteolin, apigenin, chrysoeriol and diosmetin after oral administration of Flos Chrysanthemi extract in rats

(2012) Zhongjian Chen et al.   FITOTERAPIA

A 10-year Follow-up of Triple-negative Breast Cancer Patients in Taiwan

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(2012) Daniel C. Koboldt et al.   NATURE

Inhibition of EGF/EGFR activation with naphtho[1,2-b]furan-4,5-dione blocks migration and invasion of MDA-MB-231 cells

(2012) Chi-Ying Hsieh et al.   TOXICOLOGY IN VITRO

mTOR in breast cancer: Differential expression in triple-negative and non-triple-negative tumors

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Androgen receptor expression in primary breast cancer and its predictive and prognostic value in patients treated with neoadjuvant chemotherapy

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Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

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Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells

(2010) Samir Attoub et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Expression of androgen receptors in primary breast cancer

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Androgen receptor expresion in breast cancer: Relationship with clinicopathological characteristics of the tumors, prognosis, and expression of metalloproteases and their inhibitors

(2008) Luis O Gonzalez et al.   BMC CANCER

Luteolin, a Flavonoid with Potential for Cancer Prevention and Therapy

(2008) Yong Lin et al.   CURRENT CANCER DRUG TARGETS

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