Diosmin restores the skin barrier by targeting the aryl hydrocarbon receptor in atopic dermatitis

Antioxidative Phytochemicals Accelerate Epidermal Terminal Differentiation via the AHR-OVOL1 Pathway: Implications for Atopic Dermatitis

(2018) M Furue et al.   ACTA DERMATO-VENEREOLOGICA

Differential Inflammatory-Response Kinetics of Human Keratinocytes upon Cytosolic RNA- and DNA-Fragment Induction

(2018) Judit Danis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Upregulation of FLG, LOR, and IVL Expression by Rhodiola crenulata Root Extract via Aryl Hydrocarbon Receptor: Differential Involvement of OVOL1

(2018) Akiko Hashimoto-Hachiya et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effect of diosmin on apoptotic signaling molecules in N-nitrosodiethylamine-induced hepatocellular carcinoma in experimental rats

(2018) Srinivasan Perumal et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

From TCDD-mediated toxicity to searches of physiologic AHR functions

(2018) Karl Walter Bock   BIOCHEMICAL PHARMACOLOGY

Comparative Bioavailability of Two Diosmin Formulations after Oral Administration to Healthy Volunteers

(2018) Rosario Russo et al.   MOLECULES

Anti-inflammatory and antiradical effects of a 2% diosmin cream in a human skin organ culture as model

(2018) Sylvie Boisnic et al.   Journal of Cosmetic Dermatology

Antioxidant Artemisia princeps Extract Enhances the Expression of Filaggrin and Loricrin via the AHR/OVOL1 Pathway

(2017) Akiko Hirano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapeutic pipeline for atopic dermatitis: End of the drought?

(2017) Amy S. Paller et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans

(2017) Susan H. Smith et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis

(2017) Gaku Tsuji et al.   Cell Death & Disease

Pathogenesis of atopic dermatitis

(2015) W. Peng et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Galactomycesfermentation filtrate prevents T helper 2-mediated reduction of filaggrin in an aryl hydrocarbon receptor-dependent manner

(2015) K. Takei et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

The Janus kinase inhibitor JTE-052 improves skin barrier function through suppressing signal transducer and activator of transcription 3 signaling

(2015) Wataru Amano et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Gene regulation of filaggrin and other skin barrier proteins via aryl hydrocarbon receptor

(2015) Masutaka Furue et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

AntioxidantOpuntia ficus-indicaExtract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes

(2015) Takeshi Nakahara et al.   JOURNAL OF MEDICINAL FOOD

Role of AhR/ARNT system in skin homeostasis

(2014) Masutaka Furue et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Causes of epidermal filaggrin reduction and their role in the pathogenesis of atopic dermatitis

(2014) Jacob P. Thyssen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Filaggrin mutations as an archetype for understanding the pathophysiology of atopic dermatitis

(2014) Taylor A. Banks et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Guidelines of care for the management of atopic dermatitis

(2014) Lawrence F. Eichenfield et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

The multifunctional role of filaggrin in allergic skin disease

(2013) Maeve A. McAleer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis

(2013) Ellen H. van den Bogaard et al.   JOURNAL OF CLINICAL INVESTIGATION

AhR signalling and dioxin toxicity

(2013) Olivier Sorg   TOXICOLOGY LETTERS

Differential response of normal human epidermal keratinocytes and HaCaT cells to hydrogen peroxide-induced oxidative stress

(2012) L. Liu et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Dual Oxidase 1 Induced by Th2 Cytokines Promotes STAT6 Phosphorylation via Oxidative Inactivation of Protein Tyrosine Phosphatase 1B in Human Epidermal Keratinocytes

(2011) S. Hirakawa et al.   JOURNAL OF IMMUNOLOGY

2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation

(2011) Carrie Hayes Sutter et al.   TOXICOLOGICAL SCIENCES

Skin Barrier Function in Healthy Subjects and Patients with Atopic Dermatitis in Relation to Filaggrin Loss-of-Function Mutations

(2010) Ivone Jakasa et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Target identification using drug affinity responsive target stability (DARTS)

(2009) B. Lomenick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA