Article
Chemistry, Analytical
Nan Xiang, Zhonghua Ni
Summary: In this study, a low-cost, portable, battery-driven microfluidic cell separation instrument was developed for use in resource-limited environments. The instrument integrated various technologies to achieve label-free cell separation and enrichment, and demonstrated excellent performance in terms of separation and enrichment.
ANALYTICAL CHEMISTRY
(2022)
Review
Biochemical Research Methods
Francesco Del Giudice, Gaetano D'Avino, Pier Luca Maffettone
Summary: Microfluidic devices can precisely manipulate droplets and particles, enabling the fabrication of crystal-like structures formed by hydrodynamic interactions among droplets or particles.
Article
Mathematics, Interdisciplinary Applications
Adam D. Lampropoulos, Dimitrios E. Manolakos
Summary: The study utilized the Smooth Particle Hydrodynamics (SPH) method to simulate extrusion processes with two different die cross section geometries and conducted a friction parameter analysis. The calibrated models accurately captured experimental data, effectively showcasing the influence of frictional forces on strain fields and extrusion forces.
COMPUTATIONAL PARTICLE MECHANICS
(2022)
Article
Multidisciplinary Sciences
Pan Gao, Qikun Wang, Tangjing Liu
Summary: Under the background of mechanical mechanism research for separating and screening pipeline particulate matter in microfluidic technology, this paper proposes an improved relative motion model by combining the multiple reference frame method and the relative motion model. The model can numerically calculate the aggregation features of non-spherical particles in low Reynolds number channels using a quasi-fixed constant method. The results show that elliptical particles exhibit a similar aggregation trend to circular particles when Reynolds number is between 40 and 80. The aggregation position is influenced by the ratio of long and short axes of particles, and the distribution trend is determined by the relative size of these particles. This finding provides a novel idea and method for exploring the aggregation rules of non-spherical particles and offers guidance for separating and monitoring pipeline particulate matter in microfluidic technology and industrial applications.
Article
Construction & Building Technology
Hao Sun, Yuhang Liu, Tengfei Jiang, Tong Liu, Dedi Liu
Summary: The dust produced by tunnel drilling and blasting method is a serious hazard that affects the occupational health and safety of workers. This paper systematically summarizes the dust-reducing technology for tunnel construction using drilling and blasting method, including the classification and characteristics of dust, as well as various dust wetting control technologies based on water medium. Improvement measures such as optimizing equipment parameters, combined dust control technology, and application of special materials are proposed to overcome the limitations of single dust control technology. The application of new tunnel dust control technologies is also discussed.
BUILDING AND ENVIRONMENT
(2023)
Article
Chemistry, Multidisciplinary
Yoonyoung Jung, Tae Soup Shim, Ju Min Kim
Summary: In this study, an efficient microfluidic method was proposed to measure the relaxation time of dilute polymer solutions by utilizing elasticity-driven lateral particle migration. The reliability of this method was confirmed by comparing the measured relaxation times with those obtained from Zimm theory. This approach is expected to be useful for characterizing the relaxation times of various polymer solutions.
KOREAN JOURNAL OF CHEMICAL ENGINEERING
(2022)
Article
Acoustics
Qianqing Wang, Danhui Dan
Summary: Particle dampers have received attention for their novel damping technique but lack a mature damping model due to nonlinearity. An equivalent raft model proposed in this article considers three-dimensional geometry and material properties, predicting behavior and time evolution of particles in three function modes. The model also investigates the energy dissipation mechanism of particle dampers with various parameters.
JOURNAL OF SOUND AND VIBRATION
(2022)
Article
Engineering, Chemical
Dongtao Liu, Chunshang Qiao, Jun Wan, Yuliang Lu, Jiming Song, Zhenhe Yao, Xinjie Wei, Yajun Yu
Summary: This study develops a pill particle population modelling method to optimize the anti-corrosion process of oil and gas wellbore casing annuli. The feasibility and effectiveness of the method are proven through simulation tests, demonstrating its ability to accurately simulate the pill discharging process and provide a theoretical basis for optimization.
Article
Engineering, Petroleum
Dongying Wang, Zhiming Wang
Summary: Based on the LBM-IMB-DEM model, the migration of microparticles carried by a fluid in fracture was numerically investigated. The layer-by-layer tracing method and contact detecting method were proposed and validated through experiments. The results showed that the adhesive force plays a significant role in the migration of microparticles.
Article
Construction & Building Technology
Prabhu Kumar, Hasan Mohammadi, Rajesh Chopra, Sanjeev Kumar Tyagi, Sujeet Kumar Pandey
Summary: Drilling and blasting method is widely used for tunnel excavation in hard rock. This study proposes and tests an innovative cutting system, called combined or quasi-wedge method, for small to medium-scale tunnels where traditional wedge cut is difficult to execute. The proposed drilling and blasting patterns were tested in tunnels located in Rishikesh-Karnaprayag Railway Project, Package 2, and necessary changes were made to optimize the design configurations. Compared to conventional parallel cut, the newly developed cut improves cycle time, specific drilling, and specific charge, as well as other blast parameters.
TUNNELLING AND UNDERGROUND SPACE TECHNOLOGY
(2023)
Article
Engineering, Multidisciplinary
Tao Peng, Mingyong Zhou, Shuai Yuan, Cui Fan, Bingyan Jiang
Summary: The tilted-angle standing surface acoustic wave (taSSAW) microfluidic device is a powerful tool for biosample separation, with the reliability of a numerical model being validated. Experimental validation of the numerical model's predictions, and analysis of various parameters affecting particle deflection, were conducted.
APPLIED MATHEMATICAL MODELLING
(2022)
Article
Engineering, Chemical
Seyedamirhosein Abdorahimzadeh, Feby W. Pratiwi, Seppo J. Vainio, Henrikki Liimatainen, Caglar Elbuken
Summary: The lateral migration of colloidal particles inside microfluidic channels has been investigated for its fundamental importance and potential applications in particle separation. This study experimentally explores new modes of lateral particle migration in the presence of an electric field and pressure-driven flow. The relative strengths of the electric field and pressure gradient are found to be crucial in determining particle positioning. These new migration patterns are utilized for microparticle separation and present a novel separation modality.
CHEMICAL ENGINEERING SCIENCE
(2023)
Article
Pharmacology & Pharmacy
Felicity Y. Han, Weizhi Xu, Vinod Kumar, Cedric S. Cui, Xaria Li, Xingyu Jiang, Trent M. Woodruff, Andrew K. Whittaker, Maree T. Smith
Summary: Peptides have high bioactivity and specificity, but often suffer from short circulation half-lives. This study developed a method to encapsulate peptides into nanoparticles, increasing their circulation half-life and lung distribution for improved clinical utility, particularly in treating lung-related diseases.
Article
Energy & Fuels
Masoud Outokesh, Hoseyn A. Amiri, Morteza Miansari
Summary: Particle concentration and manipulation inside droplets using magnetic forces can be predicted and optimized through numerical models. Although external magnetic force may improve separation/enrichment efficiency, careful selection of magnet position is crucial to avoid inverse effects.
CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION
(2022)
Article
Chemistry, Physical
Thejas Hulikal Chakrapani, Hanieh Bazyar, Rob G. H. Lammertink, Stefan Luding, Wouter K. den Otter
Summary: Darcy's law describes the flow of Newtonian fluids through porous media, while Brinkman extended it by adding a viscous stress term. The validity and value of Brinkman's term have been debated since its introduction.
Correction
Physics, Condensed Matter
Sascha Heitkam, Anna-Elisabeth Sommer, Wiebke Drenckhan, Jochen Froehlich
JOURNAL OF PHYSICS-CONDENSED MATTER
(2020)
Article
Materials Science, Multidisciplinary
Jean-Sebastien Kroll-Rabotin, Matthieu Gisselbrecht, Bernhard Ott, Ronja May, Jochen Froehlich, Jean-Pierre Beilot
Article
Computer Science, Interdisciplinary Applications
Silvio Tschisgale, Jochen Froehlich
JOURNAL OF COMPUTATIONAL PHYSICS
(2020)
Article
Engineering, Mechanical
Jordi Ventosa-Molina, Martin Lange, Ronald Mailach, Jochen Frohlich
Summary: This study investigated the impact of relative motion between the endwall and blade on the secondary flow structure in a linear compressor cascade through direct numerical simulations. Results showed displacement of the tip leakage vortex away from the blade and stratification of total pressure losses and exit flow angle at the outlet plane.
JOURNAL OF TURBOMACHINERY-TRANSACTIONS OF THE ASME
(2021)
Article
Engineering, Chemical
Xinghao Yang, Mark-Patrick Muhlhausen, Jochen Frohlich
Summary: This paper discusses interpolation methods for finite-size bubbles between the Euler and Lagrange phases in dispersed multiphase flow, as well as different coupling approaches, which are employed in a square bubble column reactor.
CHEMICAL ENGINEERING SCIENCE
(2021)
Article
Mechanics
Silvio Tschisgale, Bastian Loehrer, Richard Meller, Jochen Froehlich
Summary: This study investigates the fluid-structure interaction of submerged aquatic canopies, highlighting the role of coherent flow structures on the motion of vegetation elements. The results from large eddy simulation show that well-known coherent turbulent structures play a key role in creating unique turbulent features in the canopy flow.
JOURNAL OF FLUID MECHANICS
(2021)
Article
Mechanics
Ramandeep Jain, Silvio Tschisgale, Jochen Froehlich
Summary: This study investigates the influence of different non-spherical particle shapes on sediment transport through direct numerical simulations. The results show that particle shape significantly affects both fluid and particle behavior, including parameters such as porosity and bed friction. The findings highlight the importance of considering particle shape in modeling natural sediment transport processes.
JOURNAL OF FLUID MECHANICS
(2021)
Article
Thermodynamics
Tobias Hanisch, Patrick Zedler, Antonio Hurtado, Frank Ruediger, Jochen Froehlich
Summary: This study investigates thermal-hydraulic conditions in a partially uncovered nuclear fuel assembly mock-up, focusing on the influence of horizontal air flow above the rod bundle. By combining measurements and CFD simulations, it is found that all heat transfer mechanisms - conduction, convection, and radiation - are strongly coupled and of similar importance. Numerical results show good agreement with measurements, despite some inevitable differences between the approaches. The study provides important insights into factors affecting heat exchange in a spent fuel pool during accident scenarios with loss of cooling.
INTERNATIONAL JOURNAL OF HEAT AND FLUID FLOW
(2021)
Article
Mechanics
T. Hafemann, J. Froehlich
Summary: The paper presents simulations on particulate flows in square ducts with oblate and prolate particles. The positions of particle focusing are observed to be different for non-spherical particles compared to spherical ones. The rotation-induced migration of prolate particles is slower than for spheres and oblates. Increasing particle concentration leads to longer focusing time, movement towards the wall, and the formation of particle trains.
Article
Engineering, Aerospace
David Engelmann, Martin Sinkwitz, Francesca di Mare, Bjorn Koppe, Ronald Mailach, Jordi Ventosa-Molina, Jochen Frohlich, Tobias Schubert, Reinhard Niehuis
Summary: This article summarizes the collaborative research results of four research institutes on near-wall flow in turbomachinery, addressing specific questions such as the influences of boundary layer development and loss mechanisms due to secondary flow. Experimental investigations using various test rigs and measurement techniques, along with simulations, provide a comprehensive picture of the underlying phenomena in turbomachinery near-wall flow.
INTERNATIONAL JOURNAL OF TURBOMACHINERY PROPULSION AND POWER
(2021)
Article
Physics, Fluids & Plasmas
S. Tajfirooz, J. G. Meijer, J. G. M. Kuerten, M. Hausmann, J. Froehlich, J. C. H. Zeegers
Summary: The study presents a statistical learning approach using neural networks to predict hydrodynamic interactions of thin oblate spheroidal particles. By conducting simulations and training a multilayer perceptron, accurate predictions are achieved, outperforming existing empirical correlations and showing potential for future applications.
Article
Computer Science, Software Engineering
Baldwin Nsonga, Martin Niemann, Jochen Frohlich, Joachim Staib, Stefan Gumhold, Gerik Scheuermann
IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS
(2020)
Article
Computer Science, Software Engineering
Baldwin Nsonga, Gerik Scheuermann, Stefan Gumhold, Jordi Ventosa-Molina, Denis Koschichow, Jochen Froehlich
IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS
(2020)