Serotonin 6 receptor blockade reduces repetitive behavior in the BTBR mouse model of autism spectrum disorder

Cross-site Reproducibility of Social Deficits in Group-housed BTBR Mice Using Automated Longitudinal Behavioural Monitoring

(2020) Tatiana Peleh et al.   NEUROSCIENCE

Volumetric magnetic resonance and diffusion tensor imaging of C58/J mice: neural correlates of repetitive behavior

(2019) Bradley J. Wilkes et al.   Brain Imaging and Behavior

Reduction of repetitive behavior by co-administration of adenosine receptor agonists in C58 mice

(2019) Mark H. Lewis et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Citalopram attenuates social behavior deficits in the BTBR T+Itpr3tf/J mouse model of autism

(2019) Yulong Cai et al.   BRAIN RESEARCH BULLETIN

Differences in the expression of restricted repetitive behaviors in female and male BTBR T + tf/J mice

(2019) Dionisio A. Amodeo et al.   BEHAVIOURAL BRAIN RESEARCH

Virtual screening-driven discovery of dual 5-HT6/5-HT2A receptor ligands with pro-cognitive properties

(2019) Jakub Staroń et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

5-HT6 receptor agonist EMD386088 impairs behavioral flexibility and working memory

(2018) Dionisio A. Amodeo et al.   BEHAVIOURAL BRAIN RESEARCH

The role of 5 HT6-receptor antagonists in Alzheimer’s disease: an update

(2018) Rita Khoury et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Subthalamic nucleus pathology contributes to repetitive behavior expression and is reversed by environmental enrichment

(2018) M. H. Lewis et al.   GENES BRAIN AND BEHAVIOR

Clinical Research on Alzheimer’s Disease: Progress and Perspectives

(2018) Bin-Lu Sun et al.   Neuroscience Bulletin

Effects of the 5-HT 6 receptor antagonist idalopirdine on extracellular levels of monoamines, glutamate and acetylcholine in the rat medial prefrontal cortex

(2017) Arne Mørk et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Allosteric modulation of nicotinic and GABA A receptor subtypes differentially modify autism-like behaviors in the BTBR mouse model

(2017) Ryan F. Yoshimura et al.   NEUROPHARMACOLOGY

Antagonism of the 5-HT 6 receptor – Preclinical rationale for the treatment of Alzheimer's disease

(2017) Inge E.M. de Jong et al.   NEUROPHARMACOLOGY

Serotonin 5-HT6 receptors affect cognition in a mouse model of Alzheimer’s disease by regulating cilia function

(2017) Lili Hu et al.   Alzheimers Research & Therapy

Serotonin neuron abnormalities in the BTBR mouse model of autism

(2016) Yue-Ping Guo et al.   Autism Research

M100907 attenuates elevated grooming behavior in the BTBR mouse

(2016) Dionisio A. Amodeo et al.   BEHAVIOURAL BRAIN RESEARCH

Activation and blockade of serotonin6 receptors in the dorsal hippocampus enhance T maze and hole-board performance in a unilateral 6-hydroxydopamine rat model of Parkinson's disease

(2016) Kun Cheng Liu et al.   BRAIN RESEARCH

Serotonergic Drugs: Agonists/Antagonists at Specific Serotonergic Subreceptors for the Treatment of Cognitive, Depressant and Psychotic Symptoms in Alzheimer's Disease

(2016) Felix-Martin Werner et al.   CURRENT PHARMACEUTICAL DESIGN

Reducing falls in Parkinson's disease: interactions between donepezil and the 5-HT6receptor antagonist idalopirdine on falls in a rat model of impaired cognitive control of complex movements

(2016) Aaron Kucinski et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Study of a mechanism responsible for potential antidepressant activity of EMD 386088, a 5-HT6 partial agonist in rats

(2016) Magdalena Jastrzębska-Więsek et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The selective 5-HT 6 receptor antagonist SLV has putative cognitive- and social interaction enhancing properties in rodent models of cognitive impairment

(2016) N.M.W.J. de Bruin et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Reversal of social deficits by subchronic oxytocin in two autism mouse models

(2016) Brian L. Teng et al.   NEUROPHARMACOLOGY

Activation and blockade of prelimbic 5-HT 6 receptors produce different effects on depressive-like behaviors in unilateral 6-hydroxydopamine-induced Parkinson's rats

(2016) Yu-Ming Zhang et al.   NEUROPHARMACOLOGY

Striatal 5-HT6 Receptors Regulate Cocaine Reinforcement in a Pathway-Selective Manner

(2016) Matthew Brodsky et al.   NEUROPSYCHOPHARMACOLOGY

An Orally Active Phenylaminotetralin-Chemotype Serotonin 5-HT7 and 5-HT1A Receptor Partial Agonist That Corrects Motor Stereotypy in Mouse Models

(2015) Clinton E. Canal et al.   ACS Chemical Neuroscience

5-HT6 Receptor Antagonists: Potential Efficacy for the Treatment of Cognitive Impairment in Schizophrenia

(2015) Natasja de Bruin et al.   CURRENT PHARMACEUTICAL DESIGN

GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

(2015) J L Silverman et al.   NEUROPSYCHOPHARMACOLOGY

Behavioral and Neuroanatomical Phenotypes in Mouse Models of Autism

(2015) Jacob Ellegood et al.   Neurotherapeutics

Modulation of social deficits and repetitive behaviors in a mouse model of autism: the role of the nicotinic cholinergic system

(2015) Li Wang et al.   PSYCHOPHARMACOLOGY

Evaluation of the neuroactive steroid ganaxolone on social and repetitive behaviors in the BTBR mouse model of autism

(2015) Tatiana M. Kazdoba et al.   PSYCHOPHARMACOLOGY

Serotonin 5-HT6 Receptor Antagonists for the Treatment of Cognitive Deficiency in Alzheimer’s Disease

(2014) Bellinda Benhamú et al.   JOURNAL OF MEDICINAL CHEMISTRY

Potential role of the 5-HT6 receptor in depression and anxiety: an overview of preclinical data

(2014) Anna Wesołowska   Pharmacological Reports

Long-term exposure to intranasal oxytocin in a mouse autism model

(2014) K L Bales et al.   Translational Psychiatry

Repetitive behavior profile and supersensitivity to amphetamine in the C58/J mouse model of autism

(2013) Sheryl S. Moy et al.   BEHAVIOURAL BRAIN RESEARCH

Prosocial effects of oxytocin in two mouse models of autism spectrum disorders

(2013) Brian L. Teng et al.   NEUROPHARMACOLOGY

Behavioral effects of dopamine receptor inactivation during the adolescent period: age-dependent changes in dorsal striatal D2High receptors

(2013) Sanders A. McDougall et al.   PSYCHOPHARMACOLOGY

Optogenetic Stimulation of Lateral Orbitofronto-Striatal Pathway Suppresses Compulsive Behaviors

(2013) E. Burguiere et al.   SCIENCE

Further characterization of repetitive behavior in C58 mice: Developmental trajectory and effects of environmental enrichment

(2012) A.M. Muehlmann et al.   BEHAVIOURAL BRAIN RESEARCH

Low sociability in BTBR T+tf/J mice is independent of partner strain

(2012) Mu Yang et al.   PHYSIOLOGY & BEHAVIOR

Negative Allosteric Modulation of the mGluR5 Receptor Reduces Repetitive Behaviors and Rescues Social Deficits in Mouse Models of Autism

(2012) J. L. Silverman et al.   Science Translational Medicine

Differences in BTBR T+ tf/J and C57BL/6J mice on probabilistic reversal learning and stereotyped behaviors

(2011) Dionisio A. Amodeo et al.   BEHAVIOURAL BRAIN RESEARCH

5-HT6 receptor ligands, EMD386088 and SB258585, differentially regulate 5-HT6 receptor-independent events

(2011) Hyung-Mun Yun et al.   TOXICOLOGY IN VITRO

Motor and cognitive stereotypies in the BTBR T+tf/J mouse model of autism

(2010) B. L. Pearson et al.   GENES BRAIN AND BEHAVIOR

Social deficits, stereotypy and early emergence of repetitive behavior in the C58/J inbred mouse strain

(2009) Bryce C. Ryan et al.   BEHAVIOURAL BRAIN RESEARCH

Review of the Evidence for Treatment of Children with Autism with Selective Serotonin Reuptake Inhibitors

(2009) Lis West et al.   Journal for Specialists in Pediatric Nursing

Autism-like behavioral phenotypes in BTBR T+tf/J mice

(2007) H. G. McFarlane et al.   GENES BRAIN AND BEHAVIOR