Chemerin/CMKLR1 ameliorates nonalcoholic steatohepatitis by promoting autophagy and alleviating oxidative stress through the JAK2-STAT3 pathway

FXR-mediated inhibition of autophagy contributes to FA-induced TG accumulation and accordingly reduces FA-induced lipotoxicity

(2020) Kun Wu et al.   Cell Communication and Signaling

Phytotherapy using blueberry leaf polyphenols to alleviate non-alcoholic fatty liver disease through improving mitochondrial function and oxidative defense

(2020) Zheng Li et al.   PHYTOMEDICINE

Blueberry polyphenols play a preventive effect on alcoholic fatty liver disease C57BL/6 J mice by promoting autophagy to accelerate lipolysis to eliminate excessive TG accumulation in hepatocytes

(2020) Qun Zhuge et al.   Annals of Palliative Medicine

CTRP12 inhibits triglyceride synthesis and export in hepatocytes by suppressing HNF‐4α and DGAT2 expression

(2020) Stefanie Y. Tan et al.   FEBS LETTERS

Chemerin reverses neurological impairments and ameliorates neuronal apoptosis through ChemR23/CAMKK2/AMPK pathway in neonatal hypoxic–ischemic encephalopathy

(2019) Yixin Zhang et al.   Cell Death & Disease

Mechanisms of beneficial effects of exercise training on non-alcoholic fatty liver disease (NAFLD): Roles of oxidative stress and inflammation

(2019) Parvin Farzanegi et al.   European Journal of Sport Science

Pharmacological Treatment for Non-alcoholic Fatty Liver Disease

(2019) Sven Francque et al.   ADVANCES IN THERAPY

Peroxiredoxin 6 Confers Protection Against Nonalcoholic Fatty Liver Disease Through Maintaining Mitochondrial Function

(2019) Dong Hun Lee et al.   ANTIOXIDANTS & REDOX SIGNALING

Atg7-knockdown reduces chemerin secretion in murine adipocytes

(2019) Sascha Heinitz et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Resolvin E1 Ameliorates Pulpitis by Suppressing Dental Pulp Fibroblast Activation in a Chemerin Receptor 23-dependent Manner

(2019) Huaxing Xu et al.   JOURNAL OF ENDODONTICS

The Preventive Effect of Liraglutide on the Lipotoxic Liver Injury via Increasing Autophagy

(2019) Yini He et al.   Annals of Hepatology

Chemerin-9, a potent agonist of chemerin receptor (ChemR23), prevents atherogenesis

(2019) Kengo Sato et al.   CLINICAL SCIENCE

Inhibited Lipophagy Suppresses Lipid Metabolism in Zebrafish Liver Cells

(2019) Jing Wang et al.   Frontiers in Physiology

Risk of Cardiovascular Events in Patients with Hypertriglyceridemia: A Review of Real‐World Evidence

(2019) Peter P. Toth et al.   DIABETES OBESITY & METABOLISM

Triglyceride Level Is an Independent Risk Factor in First-Attacked Neuromyelitis Optica Spectrum Disorders Patients

(2019) Kaimin Wu et al.   Frontiers in Neurology

Induction of Chemerin on Autophagy and Apoptosis in Dairy Cow Mammary Epithelial Cells

(2019) Hu et al.   Animals

Chemerin-9 Peptide Enhances Memory and Ameliorates Aβ1–42-Induced Object Memory Impairment in Mice

(2019) ZeLin Lei et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Stimulation of autophagy improves vascular function in the mesenteric arteries of type 2 diabetic mice

(2019) Soo‐Kyoung Choi et al.   EXPERIMENTAL PHYSIOLOGY

Resveratrol Treatment Enhances the Cellular Response to Leptin by Increasing OBRb Content in Palmitate-Induced Steatotic HepG2 Cells

(2019) Andrea Ardid-Ruiz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Modulation of hippocampal TLR4/BDNF signal pathway using probiotics is a step closer towards treating cognitive impairment in NASH model

(2019) Safaa K. Mohammed et al.   PHYSIOLOGY & BEHAVIOR

Osteopontin acts as a negative regulator of autophagy accelerating lipid accumulation during the development of nonalcoholic fatty liver disease

(2019) Min Tang et al.   Artificial Cells Nanomedicine and Biotechnology

Role of gut microbiota and oxidative stress in the progression of non-alcoholic fatty liver disease to hepatocarcinoma: Current and innovative therapeutic approaches

(2018) Antonella Borrelli et al.   Redox Biology

Serum leptin and leptin resistance correlations with NAFLD in patients with type 2 diabetes

(2018) Simona Cernea et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Diagnostic value of chemerin in lower gastrointestinal diseases—a review

(2018) Marcin Sochal et al.   PEPTIDES

Chemerin in human cardiovascular disease

(2018) Jaspreet Kaur et al.   VASCULAR PHARMACOLOGY

The roles of SOCS3 and STAT3 in bacterial infection and inflammatory diseases

(2018) Yu Gao et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Effects of stocking density on lipid deposition and expression of lipid-related genes in Amur sturgeon (Acipenser schrenckii)

(2017) Yuanyuan Ren et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

Gax suppresses chemerin/CMKLR1-induced preadipocyte biofunctions through the inhibition of Akt/mTOR and ERK signaling pathways

(2017) Yunqi Jiang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

PI3K inhibition protects mice from NAFLD by down-regulating CMKLR1 and NLRP3 in Kupffer cells

(2017) Wenfeng Zhang et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis

(2017) Anna M. Diehl et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chemerin has a protective role in hepatocellular carcinoma by inhibiting the expression of IL-6 and GM-CSF and MDSC accumulation

(2017) Y Lin et al.   ONCOGENE

International Union of Basic and Clinical Pharmacology CIII: Chemerin Receptors CMKLR1 (Chemerin1) and GPR1 (Chemerin2) Nomenclature, Pharmacology, and Function

(2017) Amanda J. Kennedy et al.   PHARMACOLOGICAL REVIEWS

Hepatic Oncostatin M Receptor β Regulates Obesity-Induced Steatosis and Insulin Resistance

(2016) Pengcheng Luo et al.   AMERICAN JOURNAL OF PATHOLOGY

CMKLR1 deficiency influences glucose tolerance and thermogenesis in mice on high fat diet

(2016) Chen Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hepatic chemerin mRNA expression is reduced in human nonalcoholic steatohepatitis

(2016) Rebekka Pohl et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

A Combination of Mitochondrial Oxidative Stress and Excess Fat/Calorie Intake Accelerates Steatohepatitis by Enhancing Hepatic CC Chemokine Production in Mice

(2016) Tadashi Moro et al.   PLoS One

Kefir peptides prevent high-fructose corn syrup-induced non-alcoholic fatty liver disease in a murine model by modulation of inflammation and the JAK2 signaling pathway

(2016) H L Chen et al.   Nutrition & Diabetes

Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

(2014) Antonio Ayala et al.   Oxidative Medicine and Cellular Longevity

Senescence marker protein-30/superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis

(2014) Yoshitaka Kondo et al.   FEBS Open Bio

Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease

(2013) Karima Begriche et al.   HEPATOLOGY

Peripheral chemerin administration modulates hypothalamic control of feeding

(2013) Luigi Brunetti et al.   PEPTIDES

Nonalcoholic fatty liver and metabolic syndrome in Italy: results from a multicentric study of the Italian Arteriosclerosis society

(2012) Maurizio Soresi et al.   ACTA DIABETOLOGICA

Chemerin Exacerbates Glucose Intolerance in Mouse Models of Obesity and Diabetes

(2010) Matthew C. Ernst et al.   ENDOCRINOLOGY