Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing

Mutation spectrum of PRPF31, genotype-phenotype correlation in retinitis pigmentosa, and opportunities for therapy

(2020) Gabrielle Wheway et al.   EXPERIMENTAL EYE RESEARCH

MeDAS: a Metazoan Developmental Alternative Splicing database

(2020) Zhidan Li et al.   NUCLEIC ACIDS RESEARCH

Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins

(2019) Maddalen Jiménez et al.   NUCLEIC ACIDS RESEARCH

PRMT5 Modulates Splicing for Genome Integrity and Preserves Proteostasis of Hematopoietic Stem Cells

(2019) Darren Qiancheng Tan et al.   Cell Reports

Knocking out lca5 in zebrafish causes cone-rod dystrophy due to impaired outer segment protein trafficking

(2019) Zhen Qu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

PRPF31 reduction causes mis-splicing of the phototransduction genes in human organotypic retinal culture

(2019) Leila Azizzadeh Pormehr et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Retinal pigment epithelium degeneration caused by aggregation of PRPF31 and the role of HSP70 family of proteins

(2019) Lourdes Valdés-Sánchez et al.   MOLECULAR MEDICINE

Regulatory Potential of the RNA Processing Machinery: Implications for Human Disease

(2018) Kirstyn T. Carey et al.   TRENDS IN GENETICS

Neuronal Migration and Lamination in the Vertebrate Retina

(2018) Rana Amini et al.   Frontiers in Neuroscience

BCAS2 is essential for hematopoietic stem and progenitor cell maintenance during zebrafish embryogenesis

(2018) Shanshan Yu et al.   BLOOD

Splicing factors Sf3A2 and Prp31 have direct roles in mitotic chromosome segregation

(2018) Claudia Pellacani et al.   eLife

The 16p11.2 homologs fam57ba and doc2a generate certain brain and body phenotypes

(2017) Jasmine M. McCammon et al.   HUMAN MOLECULAR GENETICS

MicroRNA-9 Couples Brain Neurogenesis and Angiogenesis

(2017) Romain Madelaine et al.   Cell Reports

The downregulation of the RNA-binding protein Staufen2 in response to DNA damage promotes apoptosis

(2016) Xin Zhang et al.   NUCLEIC ACIDS RESEARCH

Spliceosomal protein eftud2 mutation leads to p53-dependent apoptosis in zebrafish neural progenitors

(2016) Lei Lei et al.   NUCLEIC ACIDS RESEARCH

An atlas of gene expression and gene co-regulation in the human retina

(2016) Michele Pinelli et al.   NUCLEIC ACIDS RESEARCH

Mutations in spliceosomal proteins and retina degeneration

(2016) Šárka Růžičková et al.   RNA Biology

Profiling DNA damage response following mitotic perturbations

(2016) Ronni S. Pedersen et al.   Nature Communications

Maternal BCAS2 protects genomic integrity in mouse early embryonic development

(2015) Qianhua Xu et al.   DEVELOPMENT

An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes

(2015) Gabrielle Wheway et al.   NATURE CELL BIOLOGY

RNA mis-splicing in disease

(2015) Marina M. Scotti et al.   NATURE REVIEWS GENETICS

Mutations in Pre-mRNA Processing Factors 3, 8, and 31 Cause Dysfunction of the Retinal Pigment Epithelium

(2014) Michael H. Farkas et al.   AMERICAN JOURNAL OF PATHOLOGY

A day in the life of the spliceosome

(2014) A. Gregory Matera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data

(2014) Shihao Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The translational landscape of the splicing factor SRSF1 and its role in mitosis

(2014) Magdalena M Maslon et al.   eLife

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Transcriptome analyses of the human retina identify unprecedented transcript diversity and 3.5 Mb of novel transcribed sequence via significant alternative splicing and novel genes

(2013) Michael H Farkas et al.   BMC GENOMICS

A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest

(2012) Makoto T Hayashi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa

(2011) Goranka Tanackovic et al.   HUMAN MOLECULAR GENETICS

SON Controls Cell-Cycle Progression by Coordinated Regulation of RNA Splicing

(2011) Eun-Young Ahn et al.   MOLECULAR CELL

Mutant Prpf31 causes pre-mRNA splicing defects and rod photoreceptor cell degeneration in a zebrafish model for Retinitis pigmentosa

(2011) Jun Yin et al.   Molecular Neurodegeneration

Efficient internal exon recognition depends on near equal contributions from the 3′ and 5′ splice sites

(2011) Peter J. Shepard et al.   NUCLEIC ACIDS RESEARCH

Dynamic usage of alternative splicing exons during mouse retina development

(2011) Jun Wan et al.   NUCLEIC ACIDS RESEARCH

Id2a influences neuron and glia formation in the zebrafish retina by modulating retinoblast cell cycle kinetics

(2010) R. A. Uribe et al.   DEVELOPMENT

Systemic splicing factor deficiency causes tissue-specific defects: a zebrafish model for retinitis pigmentosa†

(2010) Bastian Linder et al.   HUMAN MOLECULAR GENETICS

The splicing-factor related protein SFPQ/PSF interacts with RAD51D and is necessary for homology-directed repair and sister chromatid cohesion

(2010) Changanamkandath Rajesh et al.   NUCLEIC ACIDS RESEARCH

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

From Progenitors to Differentiated Cells in the Vertebrate Retina

(2009) Michalis Agathocleous et al.   Annual Review of Cell and Developmental Biology

lin9Is Required for Mitosis and Cell Survival during Early Zebrafish Development

(2009) Markus A. Kleinschmidt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability

(2009) Renee D. Paulsen et al.   MOLECULAR CELL

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS