Do behavioral pharmacology findings predict clinical trial outcomes? A proof-of-concept in medication development for alcohol use disorder

Effects of Alcohol Cue Reactivity on Subsequent Treatment Outcomes Among Treatment‐Seeking Individuals with Alcohol Use Disorder: A Multisite Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial of Varenicline

(2020) Robert Miranda et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Modeling motivation for alcohol in humans using traditional and machine learning approaches

(2020) Erica N. Grodin et al.   ADDICTION BIOLOGY

Combined Pharmacotherapy and Cognitive Behavioral Therapy for Adults With Alcohol or Substance Use Disorders

(2020) Lara A. Ray et al.   JAMA Network Open

Naltrexone effects on subjective responses to alcohol in the human laboratory: A systematic review and meta‐analysis

(2019) Lara A. Ray et al.   ADDICTION BIOLOGY

Five Priority Areas for Improving Medications Development for Alcohol Use Disorder and Promoting Their Routine Use in Clinical Practice

(2019) Raye Z. Litten et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Overcoming the “Valley of Death” in Medications Development for Alcohol Use Disorder

(2018) Lara A. Ray et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Effects of Ibudilast on the Subjective, Reinforcing, and Analgesic Effects of Oxycodone in Recently Detoxified Adults with Opioid Dependence

(2017) Verena E Metz et al.   NEUROPSYCHOPHARMACOLOGY

Development of the Neuroimmune Modulator Ibudilast for the Treatment of Alcoholism: A Randomized, Placebo-Controlled, Human Laboratory Trial

(2017) Lara A Ray et al.   NEUROPSYCHOPHARMACOLOGY

Precision Medicine in Alcohol Dependence: A Controlled Trial Testing Pharmacotherapy Response Among Reward and Relief Drinking Phenotypes

(2017) Karl Mann et al.   NEUROPSYCHOPHARMACOLOGY

Effects of naltrexone on alcohol self-administration and craving: meta-analysis of human laboratory studies

(2016) Christian S. Hendershot et al.   ADDICTION BIOLOGY

Medications development for the treatment of alcohol use disorder: insights into the predictive value of animal and human laboratory models

(2016) Megan M. Yardley et al.   ADDICTION BIOLOGY

Discovery, Development, and Adoption of Medications to Treat Alcohol Use Disorder: Goals for the Phases of Medications Development

(2016) Raye Z. Litten et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Subjective Response to Alcohol as a Research Domain Criterion

(2016) Lara A. Ray et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

A Phase 2, Double-Blind, Placebo-Controlled Randomized Trial Assessing the Efficacy of ABT-436, a Novel V1b Receptor Antagonist, for Alcohol Dependence

(2016) Megan L Ryan et al.   NEUROPSYCHOPHARMACOLOGY

Potential medications for the treatment of alcohol use disorder: An evaluation of clinical efficacy and safety

(2016) Raye Z. Litten et al.   Substance Abuse

Functional significance of subjective response to alcohol across levels of alcohol exposure

(2015) Spencer Bujarski et al.   ADDICTION BIOLOGY

Factor Structure of Subjective Responses to Alcohol in Light and Heavy Drinkers

(2015) Spencer Bujarski et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

The Effects of Naltrexone on Subjective Response to Methamphetamine in a Clinical Sample: a Double-Blind, Placebo-Controlled Laboratory Study

(2015) Lara A Ray et al.   NEUROPSYCHOPHARMACOLOGY

Conducting Meta-Analyses inRwith themetaforPackage

(2015) Wolfgang Viechtbauer   Journal of Statistical Software

Alcohol Medications Development: Advantages and Caveats of Government/Academia Collaborating with the Pharmaceutical Industry

(2014) Raye Z. Litten et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Pharmacotherapy for Adults With Alcohol Use Disorders in Outpatient Settings

(2014) Daniel E. Jonas et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Research Opportunities for Medications to Treat Alcohol Dependence: Addressing Stakeholders' Needs

(2013) Raye Z. Litten et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

A review of human drug self-administration procedures

(2013) Jermaine D. Jones et al.   BEHAVIOURAL PHARMACOLOGY

Meta-analysis of naltrexone and acamprosate for treating alcohol use disorders: when are these medications most helpful?

(2012) Natalya C. Maisel et al.   ADDICTION

Medications development to treat alcohol dependence: a vision for the next decade

(2012) Raye Z. Litten et al.   ADDICTION BIOLOGY

Rewarding, Stimulant, and Sedative Alcohol Responses and Relationship to Future Binge Drinking

(2011) Andrea C. King et al.   ARCHIVES OF GENERAL PSYCHIATRY

Critical thoughts on current rodent models for evaluating potential treatments of alcohol addiction and withdrawal

(2011) Tamzin L Ripley et al.   BRITISH JOURNAL OF PHARMACOLOGY

Application of Human Laboratory Models to Pharmacotherapy Development for Alcohol Dependence

(2010) Lara A. Ray et al.   CURRENT PHARMACEUTICAL DESIGN

Catching the Alcohol Buzz: An Examination of the Latent Factor Structure of Subjective Intoxication

(2009) Lara A. Ray et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Translating the neuroscience of alcoholism into clinical treatments: From blocking the buzz to curing the blues

(2009) Markus Heilig et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The role of human drug self-administration procedures in the development of medications

(2008) S.D. Comer et al.   DRUG AND ALCOHOL DEPENDENCE