Naturalizing mouse models for immunology

Natural resistance to worms exacerbates bovine tuberculosis severity independently of worm coinfection

(2021) Vanessa O. Ezenwa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune-Endocrine Links to Gregariousness in Wild House Mice

(2020) Patricia C. Lopes et al.   Frontiers in Behavioral Neuroscience

Altered Immunity of Laboratory Mice in the Natural Environment Is Associated with Fungal Colonization

(2020) Frank Yeung et al.   Cell Host & Microbe

Rewilding Nod2 and Atg16l1 Mutant Mice Uncovers Genetic and Environmental Contributions to Microbial Responses and Immune Cell Composition

(2020) Jian-Da Lin et al.   Cell Host & Microbe

A Good Life for Laboratory Rodents?

(2020) I Joanna Makowska et al.   ILAR JOURNAL

Brain control of humoral immune responses amenable to behavioural modulation

(2020) Xu Zhang et al.   NATURE

Interleukin-13 drives metabolic conditioning of muscle to endurance exercise

(2020) Nelson H. Knudsen et al.   SCIENCE

Inferring the immune response from repertoire sequencing

(2020) Maximilian Puelma Touzel et al.   PLoS Computational Biology

Origin and Function of Stress-Induced IL-6 in Murine Models

(2020) Hua Qing et al.   CELL

New Insights into the Immune System Using Dirty Mice

(2020) Sara E. Hamilton et al.   JOURNAL OF IMMUNOLOGY

Rewilding immunology

(2020) Andrew S. Flies et al.   SCIENCE

Immune state is associated with natural dietary variation in wild mice Mus musculus domesticus

(2019) Christopher H. Taylor et al.   FUNCTIONAL ECOLOGY

What is the best housing temperature to translate mouse experiments to humans?

(2019) Jaap Keijer et al.   Molecular Metabolism

Circadian and Circannual Timescales Interact to Generate Seasonal Changes in Immune Function

(2019) Kenneth G. Onishi et al.   BRAIN BEHAVIOR AND IMMUNITY

Laboratory mice born to wild mice have natural microbiota and model human immune responses

(2019) Stephan P. Rosshart et al.   SCIENCE

The circadian clock of CD8 T cells modulates their early response to vaccination and the rhythmicity of related signaling pathways

(2019) Chloé C. Nobis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Senescence in immunity against helminth parasites predicts adult mortality in a wild mammal

(2019) H. Froy et al.   SCIENCE

Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells

(2019) Vanessa Frodermann et al.   NATURE MEDICINE

Trickle infection and immunity to Trichuris muris

(2019) Maya Glover et al.   PLoS Pathogens

Neutrophil extracellular traps drive inflammatory pathogenesis in malaria

(2019) Sebastian Lorenz Knackstedt et al.   Science Immunology

Neutrophil‐endothelial interactions of murine cells is not a good predictor of their interactions in human cells

(2019) Fariborz Soroush et al.   FASEB JOURNAL

The Emerging Role of Neutrophils in Repair after Acute Lung Injury

(2018) Jorge Blázquez-Prieto et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Unraveling the Complex Interplay Between T Cell Metabolism and Function

(2018) Ramon I. Klein Geltink et al.   Annual Review of Immunology

A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling

(2018) Christoph Schneider et al.   CELL

The gut microbiota of wild rodents: Challenges and opportunities

(2018) Mark Viney   LABORATORY ANIMALS

Neural Mechanisms of Inflammation-Induced Fever

(2018) Anders Blomqvist et al.   NEUROSCIENTIST

The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock

(2018) Thomas W. Hopwood et al.   Scientific Reports

Rapid environmental effects on gut nematode susceptibility in rewilded mice

(2018) Jacqueline M. Leung et al.   PLOS BIOLOGY

The ecology of immune state in a wild mammal, Mus musculus domesticus

(2018) Stephen Abolins et al.   PLOS BIOLOGY

Feeding Immunity: Physiological and Behavioral Responses to Infection and Resource Limitation

(2018) Sarah A. Budischak et al.   Frontiers in Immunology

Optimal housing temperatures for mice to mimic the thermal environment of humans: An experimental study

(2018) Alexander W. Fischer et al.   Molecular Metabolism

The effects of living in an outdoor enclosure on hippocampal plasticity and anxiety-like behavior in response to nematode infection

(2018) Elise C. Cope et al.   HIPPOCAMPUS

Lymphocyte Circadian Clocks Control Lymph Node Trafficking and Adaptive Immune Responses

(2017) David Druzd et al.   IMMUNITY

Of Mice, Dirty Mice, and Men: Using Mice To Understand Human Immunology

(2017) David Masopust et al.   JOURNAL OF IMMUNOLOGY

Warming the mouse to model human diseases

(2017) Kirthana Ganeshan et al.   Nature Reviews Endocrinology

Continuous immunotypes describe human immune variation and predict diverse responses

(2017) Kevin J. Kaczorowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Making Mouse Models That Reflect Human Immune Responses

(2017) Lili Tao et al.   TRENDS IN IMMUNOLOGY

The comparative immunology of wild and laboratory mice, Mus musculus domesticus

(2017) Stephen Abolins et al.   Nature Communications

Sequential Infection with Common Pathogens Promotes Human-like Immune Gene Expression and Altered Vaccine Response

(2016) Tiffany A. Reese et al.   Cell Host & Microbe

Quantification of cerivastatin toxicity supports organismal performance assays as an effective tool during pharmaceutical safety assessment

(2016) Shannon M. Gaukler et al.   Evolutionary Applications

Reassessing the Evolutionary Importance of Inflammasomes

(2016) Vivien I. Maltez et al.   JOURNAL OF IMMUNOLOGY

Normalizing the environment recapitulates adult human immune traits in laboratory mice

(2016) Lalit K. Beura et al.   NATURE

Composition of the gut microbiota modulates the severity of malaria

(2016) Nicolas F. Villarino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helminth infection promotes colonization resistance via type 2 immunity

(2016) Deepshika Ramanan et al.   SCIENCE

Releasing the Brakes on Cancer Immunotherapy

(2015) Dan R. Littman   CELL

Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences

(2015) Petter Brodin et al.   CELL

Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium

(2015) Vivien I. Maltez et al.   IMMUNITY

Natural selection against a circadian clock gene mutation in mice

(2015) Kamiel Spoelstra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens

(2014) Nora Branzk et al.   NATURE IMMUNOLOGY

Neuro-Endocrine Networks Controlling Immune System in Health and Disease

(2014) Claudio Procaccini et al.   Frontiers in Immunology

Into the wild: digging at immunology's evolutionary roots

(2013) Rick M Maizels et al.   NATURE IMMUNOLOGY

Animals in a bacterial world, a new imperative for the life sciences

(2013) Margaret McFall-Ngai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emergence of Individuality in Genetically Identical Mice

(2013) J. Freund et al.   SCIENCE

An evolutionary ecology of individual differences

(2012) Sasha R. X. Dall et al.   ECOLOGY LETTERS

Unstressing intemperate models: how cold stress undermines mouse modeling

(2012) Christopher L. Karp   JOURNAL OF EXPERIMENTAL MEDICINE

A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes

(2012) D. G. MacArthur et al.   SCIENCE

Not so hot: Optimal housing temperatures for mice to mimic the thermal environment of humans

(2012) John R. Speakman et al.   Molecular Metabolism

Wild immunology

(2011) AMY B. PEDERSEN et al.   MOLECULAR ECOLOGY

Systems Vaccinology

(2010) Bali Pulendran et al.   IMMUNITY

Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors

(2010) A. K. Benson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fitness Correlates of Heritable Variation in Antibody Responsiveness in a Wild Mammal

(2010) Andrea L. Graham et al.   SCIENCE

t Testing the Immune System

(2008) Tracey J. Lamb et al.   IMMUNITY