Endogenous promoter-driven sgRNA for monitoring the expression of low-abundance transcripts and lncRNAs

A microRNA-inducible CRISPR–Cas9 platform serves as a microRNA sensor and cell-type-specific genome regulation tool

(2019) Xi-Wen Wang et al.   NATURE CELL BIOLOGY

Systematic identification and characterization of Aedes aegypti long noncoding RNAs (lncRNAs)

(2019) Azali Azlan et al.   Scientific Reports

An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance

(2018) Assaf C. Bester et al.   CELL

In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR–dCas9-activator transgenic mice

(2018) Haibo Zhou et al.   NATURE NEUROSCIENCE

The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway

(2018) Zihao Sun et al.   Stem Cell Reports

CRISPR Activation Screens Systematically Identify Factors that Drive Neuronal Fate and Reprogramming

(2018) Yanxia Liu et al.   Cell Stem Cell

Tissue Expression Difference between mRNAs and lncRNAs

(2018) Lei Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Riboregulated toehold-gated gRNA for programmable CRISPR–Cas9 function

(2018) Ka-Hei Siu et al.   Nature Chemical Biology

Complex cellular logic computation using ribocomputing devices

(2017) Alexander A. Green et al.   NATURE

Virus-Mediated Genome Editing via Homology-Directed Repair in Mitotic and Postmitotic Cells in Mammalian Brain

(2017) Jun Nishiyama et al.   NEURON

Cell-type-specific genome editing with a microRNA-responsive CRISPR–Cas9 switch

(2017) Moe Hirosawa et al.   NUCLEIC ACIDS RESEARCH

High-Throughput, High-Resolution Mapping of Protein Localization in Mammalian Brain by In Vivo Genome Editing

(2016) Takayasu Mikuni et al.   CELL

Directing cellular information flow via CRISPR signal conductors

(2016) Yuchen Liu et al.   NATURE METHODS

Efficient Detection and Purification of Cell Populations Using Synthetic MicroRNA Switches

(2015) Kenji Miki et al.   Cell Stem Cell

Highly efficient Cas9-mediated transcriptional programming

(2015) Alejandro Chavez et al.   NATURE METHODS

TET1 is controlled by pluripotency-associated factors in ESCs and downmodulated by PRC2 in differentiated cells and tissues

(2015) Francesco Neri et al.   NUCLEIC ACIDS RESEARCH

Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system

(2015) Kabin Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterogeneous lineage marker expression in naive embryonic stem cells is mostly due to spontaneous differentiation

(2015) Gautham Nair et al.   Scientific Reports

Generation of cell-type-specific gene mutations by expressing the sgRNA of the CRISPR system from the RNA polymerase II promoters

(2015) Jiaqiang Wang et al.   Protein & Cell

Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution

(2015) Moran N Cabili et al.   GENOME BIOLOGY

Neural Differentiation of Mouse Embryonic Stem Cells in Serum-free Monolayer Culture

(2015) Wikrom Wongpaiboonwattana et al.   Jove-Journal of Visualized Experiments

Toehold Switches: De-Novo-Designed Regulators of Gene Expression

(2014) Alexander A. Green et al.   CELL

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

Multiplexed and Programmable Regulation of Gene Networks with an Integrated RNA and CRISPR/Cas Toolkit in Human Cells

(2014) Lior Nissim et al.   MOLECULAR CELL

Integration of Genome-wide Approaches Identifies lncRNAs of Adult Neural Stem Cells and Their Progeny In Vivo

(2013) Alexander D. Ramos et al.   Cell Stem Cell

Two Pore Channel 2 Differentially Modulates Neural Differentiation of Mouse Embryonic Stem Cells

(2013) Zhe-Hao Zhang et al.   PLoS One

Multiple knockout mouse models reveal lincRNAs are required for life and brain development

(2013) Martin Sauvageau et al.   eLife

Control of somatic tissue differentiation by the long non-coding RNA TINCR

(2012) Markus Kretz et al.   NATURE

Modular regulatory principles of large non-coding RNAs

(2012) Mitchell Guttman et al.   NATURE