Bioassay-Guided Isolation of Anti-Alzheimer Active Components from the Aerial Parts of Hedyotis diffusa and Simultaneous Analysis for Marker Compounds

Inhibitory Effect of Chemical Constituents Isolated from Artemisia iwayomogi on Polyol Pathway and Simultaneous Quantification of Major Bioactive Compounds

(2017) Yoon Kyoung Lee et al.   Biomed Research International

Subcritical Water Extraction of Ursolic Acid from Hedyotis diffusa

(2017) Shangzhen Xiao et al.   Applied Sciences-Basel

Bioactive phenols as potential neuroinflammation inhibitors from the leaves of Xanthoceras sorbifolia Bunge

(2016) Ning Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Hedyotis diffusa Willd. (Rubiaceae): A Review on Phytochemistry, Pharmacology, Quality Control and Pharmacokinetics

(2016) Rui Chen et al.   MOLECULES

Anticancer Effects of 1,3-Dihydroxy-2-Methylanthraquinone and the Ethyl Acetate Fraction of Hedyotis Diffusa Willd against HepG2 Carcinoma Cells Mediated via Apoptosis

(2016) Yun-lan Li et al.   PLoS One

The Study of the Effect of Hedyotis diffusa on the Proliferation and the Apoptosis of the Cervical Tumor in Nude Mouse Model

(2015) Peiying Zhang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Total flavonoids of Hedyotis diffusa Willd inhibit inflammatory responses in LPS-activated macrophages via suppression of the NF-κB and MAPK signaling pathways

(2015) YUNLONG CHEN et al.   Experimental and Therapeutic Medicine

Targeting the β secretase BACE1 for Alzheimer's disease therapy

(2014) Riqiang Yan et al.   LANCET NEUROLOGY

Separation and Purification of Bioactive Flavonol Glycosides fromHedyotis diffusaWilld by High-Speed Counter-Current Chromatography

(2011) Qingfa Tang et al.   SEPARATION SCIENCE AND TECHNOLOGY

Two new iridoid glucosides from Hedyotis diffusa

(2010) Yongyong Zhang et al.   FITOTERAPIA

Biologically Active Iridoids from Hedyotis diffusa

(2010) Bo Ding et al.   HELVETICA CHIMICA ACTA

Alzheimer's disease: strategies for disease modification

(2010) Martin Citron   NATURE REVIEWS DRUG DISCOVERY

The amyloid hypothesis for Alzheimer’s disease: a critical reappraisal

(2009) John Hardy   JOURNAL OF NEUROCHEMISTRY