Bacterial Alkyl-4-quinolones: Discovery, Structural Diversity and Biological Properties

Development and bioanalytical method validation of an LC-MS/MS assay for simultaneous quantitation of 2-alkyl-4(1H)-quinolones for application in bacterial cell culture and lung tissue

(2020) Luke K. Brewer et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Burkholderia thailandensis outer membrane vesicles exert antimicrobial activity against drug-resistant and competitor microbial species

(2020) Yihui Wang et al.   JOURNAL OF MICROBIOLOGY

4-Hydroxy-3-methyl-2(1H)-quinolone, originally discovered from a Brassicaceae plant, produced by a soil bacterium of the genus Burkholderia sp.: determination of a preferred tautomer and antioxidant activity

(2020) Dandan Li et al.   Beilstein Journal of Organic Chemistry

Synthesis and Antimicrobial Activity of Burkholderia-Related 4-Hydroxy-3-methyl-2-alkenylquinolines (HMAQs) and Their N-Oxide Counterparts

(2020) Marianne Piochon et al.   JOURNAL OF NATURAL PRODUCTS

Isolation of 2-Alkyl-4-quinolones with Unusual Side Chains from a Chinese Pseudomonas aeruginosa Isolate

(2020) Jianye Li et al.   JOURNAL OF NATURAL PRODUCTS

Synthesis of Natural and Unnatural Quinolones Inhibiting the Growth and Motility of Bacteria

(2020) Jianye Li et al.   JOURNAL OF NATURAL PRODUCTS

Therapeutic Targeting of the IGF Axis

(2019) Eliot Osher et al.   Cells

Recent advances in the synthetic and medicinal perspective of quinolones: A review

(2019) Prashant Dhiman et al.   BIOORGANIC CHEMISTRY

Alkaloids with Nitric Oxide Inhibitory Activities from the Roots of Isatis tinctoria

(2019) Dongdong Zhang et al.   MOLECULES

Two new 2-alkylquinolones, inhibitory to the fish skin ulcer pathogen Tenacibaculum maritimum, produced by a rhizobacterium of the genus Burkholderia sp.

(2018) Dandan Li et al.   Beilstein Journal of Organic Chemistry

Pseudane-VII Regulates LPS-Induced Neuroinflammation in Brain Microglia Cells through the Inhibition of iNOS Expression

(2018) Mi Kim et al.   MOLECULES

Design, synthesis and antitubercular potency of 4-hydroxyquinolin-2(1 H )-ones

(2017) Maíra Bidart de Macedo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Aurachin SS, a new antibiotic from Streptomyces sp. NA04227

(2017) Mei Zhang et al.   JOURNAL OF ANTIBIOTICS

Clustering of MS 2 spectra using unsupervised methods to aid the identification of secondary metabolites from Pseudomonas aeruginosa

(2017) Tobias Depke et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Pseudane-VII Isolated from Pseudoalteromonas sp. M2 Ameliorates LPS-Induced Inflammatory Response In Vitro and In Vivo

(2017) Mi Kim et al.   Marine Drugs

Pseudomonas aeruginosa exoproducts determine antibiotic efficacy against Staphylococcus aureus

(2017) Lauren Radlinski et al.   PLOS BIOLOGY

Designed Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosa

(2016) Cheng Ji et al.   ACS Chemical Biology

Mapping the Trimethoprim-Induced Secondary Metabolome of Burkholderia thailandensis

(2016) Bethany K. Okada et al.   ACS Chemical Biology

Auto Poisoning of the Respiratory Chain by a Quorum-Sensing-Regulated Molecule Favors Biofilm Formation and Antibiotic Tolerance

(2016) Ronen Hazan et al.   CURRENT BIOLOGY

Liquid Chromatography-Mass Spectrometry-Based Rapid Secondary-Metabolite Profiling of Marine Pseudoalteromonas sp. M2

(2016) Woo Kim et al.   Marine Drugs

Antimicrobial and anti-oxidant activities of quinoline alkaloids from Pseudomonas aeruginosa BCC76810

(2016) Khomsan Supong et al.   Phytochemistry Letters

Burkholderia pseudomallei kynB plays a role in AQ production, biofilm formation, bacterial swarming and persistence

(2016) Aaron Butt et al.   RESEARCH IN MICROBIOLOGY

A new Pseudomonas quinolone signal (PQS) binding partner: MexG

(2016) James T. Hodgkinson et al.   Chemical Science

The role of 2,4-dihydroxyquinoline (DHQ) inPseudomonas aeruginosapathogenicity

(2016) Jordon D. Gruber et al.   PeerJ

PqsE of Pseudomonas aeruginosa Acts as Pathway-Specific Thioesterase in the Biosynthesis of Alkylquinolone Signaling Molecules

(2015) Steffen Lorenz Drees et al.   CHEMISTRY & BIOLOGY

The Pseudomonas Quinolone Signal (PQS)

(2015) Thomas Sams et al.   ISRAEL JOURNAL OF CHEMISTRY

Iron Depletion Enhances Production of Antimicrobials by Pseudomonas aeruginosa

(2015) Angela T. Nguyen et al.   JOURNAL OF BACTERIOLOGY

The Pseudomonas Quinolone Signal Inhibits Biofilm Development of Streptococcus mutans

(2015) Tomohiro Inaba et al.   MICROBES AND ENVIRONMENTS

Inhibition of hepatitis C virus replication by chalepin and pseudane IX isolated from Ruta angustifolia leaves

(2014) Tutik Sri Wahyuni et al.   FITOTERAPIA

The End of an Old Hypothesis: The Pseudomonas Signaling Molecules 4-Hydroxy-2-Alkylquinolines Derive from Fatty Acids, Not 3-Ketofatty Acids

(2013) Carlos Eduardo Dulcey et al.   CHEMISTRY & BIOLOGY

Membrane vesicle formation is associated with pyocin production under denitrifying conditions inPseudomonas aeruginosa PAO1

(2013) Masanori Toyofuku et al.   ENVIRONMENTAL MICROBIOLOGY

Algicidal Activity of MarineAlteromonassp. KNS-16 and Isolation of Active Compounds

(2012) Ji Young CHO   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

The Multiple Signaling Systems Regulating Virulence in Pseudomonas aeruginosa

(2012) P. Nadal Jimenez et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Structure–function analysis of the C-3 position in analogues of microbial behavioural modulators HHQ and PQS

(2012) F. Jerry Reen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and biotransformation of 2-alkyl-4(1H)-quinolones by recombinant Pseudomonas putida KT2440

(2011) Heiko Niewerth et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Environmental Burkholderia cepacia Strain Cs5 Acting by Two Analogous Alkyl-Quinolones and a Didecyl-Phthalate Against a Broad Spectrum of Phytopathogens Fungi

(2011) Olfa Kilani-Feki et al.   CURRENT MICROBIOLOGY

Pseudomonas aeruginosa Inhibits the Growth of Cryptococcus Species

(2011) Antonella Rella et al.   MYCOPATHOLOGIA

The Pseudomonas aeruginosa quinolone quorum sensing signal alters the multicellular behaviour of Pseudomonas putida KT2440

(2011) Regina Fernández-Piñar et al.   RESEARCH IN MICROBIOLOGY

Correlation between synthesis variation of 2-alkylquinolones and the antifungal activity of a Burkholderia cepacia strain collection

(2011) Olfa Kilani-Feki et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Two new aurachins from Rhodococcus sp. Acta 2259

(2010) Jonny Nachtigall et al.   JOURNAL OF ANTIBIOTICS

The Effect of a Cell-to-Cell Communication Molecule, Pseudomonas Quinolone Signal (PQS), Produced by P. aeruginosa on Other Bacterial Species

(2010) Masanori Toyofuku et al.   MICROBES AND ENVIRONMENTS

Oxygen levels rapidly modulate Pseudomonas aeruginosa social behaviours via substrate limitation of PqsH

(2010) Jeffrey W. Schertzer et al.   MOLECULAR MICROBIOLOGY

Antivibrio compounds produced by Pseudomonas sp. W3: characterisation and assessment of their safety to shrimps

(2010) Pattamarat Rattanachuay et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

A Quinoline Antibiotic from Rhodococcus erythropolis JCM 6824

(2009) Wataru Kitagawa et al.   JOURNAL OF ANTIBIOTICS

Burkholderia pseudomallei, B. thailandensis, and B. ambifaria Produce 4-Hydroxy-2-Alkylquinoline Analogues with a Methyl Group at the 3 Position That Is Required for Quorum-Sensing Regulation

(2008) L. Vial et al.   JOURNAL OF BACTERIOLOGY

PqsD Is Responsible for the Synthesis of 2,4-Dihydroxyquinoline, an Extracellular Metabolite Produced byPseudomonas aeruginosa

(2008) Yong-Mei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quorum sensing by 2-alkyl-4-quinolones in Pseudomonas aeruginosa and other bacterial species

(2008) Jean-Frédéric Dubern et al.   Molecular BioSystems

The Pseudomonas Quinolone Signal (PQS) Balances Life and Death in Pseudomonas aeruginosa Populations

(2008) Susanne Häussler et al.   PLoS Pathogens