The Center Cannot Hold: NRF2 Battles Ferroptosis in the 3rd Dimension

Mechanical regulation of glycolysis via cytoskeleton architecture

(2020) Jin Suk Park et al.   NATURE

CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities

(2020) Kyuho Han et al.   NATURE

Lymph protects metastasizing melanoma cells from ferroptosis

(2020) Jessalyn M. Ubellacker et al.   NATURE

3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis

(2020) Nobuaki Takahashi et al.   MOLECULAR CELL

Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1

(2019) Luca Lignitto et al.   CELL

The Roles of NRF2 in Modulating Cellular Iron Homeostasis

(2017) Michael John Kerins et al.   ANTIOXIDANTS & REDOX SIGNALING

Antioxidants Accelerate Lung Cancer Progression in Mice

(2014) V. I. Sayin et al.   Science Translational Medicine

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

(2012) Yoichiro Mitsuishi et al.   CANCER CELL

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

(2009) Zachary T. Schafer et al.   NATURE