Journal
MICROCHEMICAL JOURNAL
Volume 159, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.microc.2020.105509
Keywords
Flutamide sensor; CeVO4; Hydrothermal method; Electrochemical sensor; Biological samples
Categories
Funding
- Ministry of Science and Technology [MOST 107-2113-M-027 -005 -MY3]
- Taiwan (ROC) [RSP-2020/247]
- King Saud University, Riyadh, Saudi Arabia
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Herein, we reported the synthesis of cerium orthovanadate nanorods (CeVO4-NRs) using the hydrothermal methodology and its excellent performance towards the detection of anti-prostate cancer drug flutamide (FLA) sensing in biological samples. The size and structural properties of the as-prepared CeVO4-NRs was characterized through the FESEM and HRTEM. Moreover, the optical properties and chemical composition of the CeVO4-NRs was configured by the Fourier transform infrared spectroscopy (FTIR), UV-Vis spectrophotometer, XRD and Raman spectroscopy. The electrocatalytic activity of CeVO4-NRs towards the detection of FLA was scrutinized through cyclic voltammetry (CV) and DPV techniques. Besides, the fabricated sensor possessed the covering range of 0.01to 57 mu M and 75.26 to 507.94 mu M with a lower detection limit of 1.94 nM. At the end, the FLA detection in real samples of human blood serum and urine samples at CeVO4-NRs/GCE exhibited acceptable found and recovery values.
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