Insulin receptor isoform A ameliorates long-term glucose intolerance in diabetic mice

Pathogenesis of Selective Insulin Resistance in Isolated Hepatocytes

(2015) Joshua R. Cook et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin receptor isoform A confers a higher proliferative capability to pancreatic beta cells enabling glucose availability and IGF-I signaling

(2015) Oscar Escribano et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Aberrant Liver Insulin Receptor Isoform A Expression Normalises with Remission of Type 2 Diabetes after Gastric Bypass Surgery

(2015) Vinko Besic et al.   PLoS One

Mitogenic Insulin Receptor-A Is Overexpressed in Human Hepatocellular Carcinoma due to EGFR-Mediated Dysregulation of RNA Splicing Factors

(2013) Hamza Chettouh et al.   CANCER RESEARCH

Treatment of Diabetes and Long-Term Survival After Insulin and Glucokinase Gene Therapy

(2013) D. Callejas et al.   DIABETES

How insulin engages its primary binding site on the insulin receptor

(2013) John G. Menting et al.   NATURE

IL12-Mediated Liver Inflammation Reduces the Formation of AAV Transcriptionally Active Forms but Has No Effect over Preexisting AAV Transgene Expression

(2013) Irene Gil-Fariña et al.   PLoS One

Liver-Derived Systemic Factors Drive β Cell Hyperplasia in Insulin-Resistant States

(2013) Abdelfattah El Ouaamari et al.   Cell Reports

Association between tamoxifen treatment and diabetes

(2011) Lorraine L. Lipscombe et al.   CANCER

The Insulin Receptor: A New Target for Cancer Therapy

(2011) Roberta Malaguarnera et al.   Frontiers in Endocrinology

Significant Human β-Cell Turnover Is Limited to the First Three Decades of Life as Determined byin VivoThymidine Analog Incorporation and Radiocarbon Dating

(2010) S. Perl et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ligand-induced activation of the insulin receptor: a multi-step process involving structural changes in both the ligand and the receptor

(2009) Colin W. Ward et al.   BIOESSAYS

 -Cell Hyperplasia Induced by Hepatic Insulin Resistance: Role of a Liver-Pancreas Endocrine Axis Through Insulin Receptor A Isoform

(2009) O. Escribano et al.   DIABETES

Maternal undernutrition increases pancreatic IGF-2 and partially suppresses the physiological wave of β-cell apoptosis during the neonatal period

(2009) Laura de Miguel-Santos et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Glucose Effects on Beta-Cell Growth and Survival Require Activation of Insulin Receptors and Insulin Receptor Substrate 2

(2009) A. Assmann et al.   MOLECULAR AND CELLULAR BIOLOGY

Expansion of β-cell mass in response to pregnancy

(2009) Sebastian Rieck et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Selective versus Total Insulin Resistance: A Pathogenic Paradox

(2008) Michael S. Brown et al.   Cell Metabolism

 -Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of  -Cell Mass in Humans

(2008) J. J. Meier et al.   DIABETES

Prolactin Receptor Is Required for Normal Glucose Homeostasis and Modulation of β-Cell Mass during Pregnancy

(2008) Carol Huang et al.   ENDOCRINOLOGY

Potential of AAV vectors in the treatment of metabolic disease

(2008) I E Alexander et al.   GENE THERAPY

Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes

(2008) Deborah M. Muoio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY