Type VI collagen and its cleavage product, endotrophin, cooperatively regulate the adipogenic and lipolytic capacity of adipocytes

C-terminal proteolysis of the collagen VI α3 chain by BMP-1 and proprotein convertase(s) releases endotrophin in fragments of different sizes

(2019) Stefanie Elisabeth Heumüller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ascorbic acid promotes 3T3-L1 cells adipogenesis by attenuating ERK signaling to upregulate the collagen VI

(2017) Chuanguo Liu et al.   Nutrition & Metabolism

JNK at the crossroad of obesity, insulin resistance, and cell stress response

(2017) Giovanni Solinas et al.   Molecular Metabolism

Divergent functions of endotrophin on different cell populations in adipose tissue

(2016) Yueshui Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Endotrophin, a multifaceted player in metabolic dysregulation and cancer progression, is a predictive biomarker for the response to PPARγ agonist treatment

(2016) Kai Sun et al.   DIABETOLOGIA

Heterogeneity of Collagen VI Microfibrils

(2016) Tobias Maaß et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced expression of collagen VI alpha 3 (COL6A3) confers resistance to inflammation-induced MCP1 expression in adipocytes

(2016) Stephane Gesta et al.   Obesity

Dynamics of protein secretion during adipocyte differentiation

(2016) Koichi Ojima et al.   FEBS Open Bio

Collagen VI at a glance

(2015) M. Cescon et al.   JOURNAL OF CELL SCIENCE

The roles of c-Jun NH2-terminal kinases (JNKs) in obesity and insulin resistance

(2015) Martin Pal et al.   JOURNAL OF PHYSIOLOGY-LONDON

Cross-talk between Endoplasmic Reticulum (ER) Stress and the MEK/ERK Pathway Potentiates Apoptosis in Human Triple Negative Breast Carcinoma Cells

(2014) Swatilekha Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction

(2014) Kai Sun et al.   Nature Communications

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The expanded collagen VI family: new chains and new questions

(2013) Jamie Fitzgerald et al.   CONNECTIVE TISSUE RESEARCH

Inhibition of endotrophin, a cleavage product of collagen VI, confers cisplatin sensitivity to tumours

(2013) Jiyoung Park et al.   EMBO Molecular Medicine

Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases

(2013) Y. H. Sung et al.   GENOME RESEARCH

COL6A3 Protein Deficiency in Mice Leads to Muscle and Tendon Defects Similar to Human Collagen VI Congenital Muscular Dystrophy

(2013) Te-Cheng Pan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipocyte-derived endotrophin promotes malignant tumor progression

(2012) Jiyoung Park et al.   JOURNAL OF CLINICAL INVESTIGATION

New insights into ER stress-induced insulin resistance

(2012) Mélissa Flamment et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The Fat Controller: Adipocyte Development

(2012) Jacqueline M. Stephens   PLOS BIOLOGY

Genetic ablation of cyclophilin D rescues mitochondrial defects and prevents muscle apoptosis in collagen VI myopathic mice

(2009) Elena Palma et al.   HUMAN MOLECULAR GENETICS

Stimulation of osteogenic differentiation and inhibition of adipogenic differentiation in bone marrow stromal cells by alendronate via ERK and JNK activation

(2008) Lingjie Fu et al.   BONE

Three Novel Collagen VI Chains, α4(VI), α5(VI), and α6(VI)

(2008) Jamie Fitzgerald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI

(2008) T. Khan et al.   MOLECULAR AND CELLULAR BIOLOGY

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

(2008) Adilson Guilherme et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY