Article
Genetics & Heredity
Marlies Monnens, Ali Halajian, D. Tim J. Littlewood, Andrew G. Briscoe, Tom Artois, Maarten P. M. Vanhove
Summary: This study characterizes a new mitochondrial genome for Clinostomum complanatum and reveals the population structure of this parasitic flatworm. It suggests that genetic exchange between different geographic populations of C. complanatum is facilitated by avian migratory routes. The study also highlights the importance of using new or additional mitochondrial markers for high-resolution diagnostics and population biology.
Article
Toxicology
Colin M. North, A. Robert Schnatter, Martijn Rooseboom, Neslihan Aygun Kocabas, Abigail Dalzell, Stephen D. Williams
Summary: Occupational exposure to benzene at levels of 10 ppm or more is associated with increased risk of acute myeloid leukaemia (AML). Preventing early key events can lead to prevention of adverse outcomes caused by myelodysplastic syndromes (MDS) and AML, and modification approaches using sub-linear and segmented linear increases in risk have been suggested. Incorporating key event information into risk models provides greater flexibility in risk model development and selection.
TOXICOLOGY LETTERS
(2021)
Article
Evolutionary Biology
Rafael R. Ferrari, Thiago M. Batista, Qing-Song Zhou, Heron O. Hilario, Michael C. Orr, Arong Luo, Chao-Dong Zhu
Summary: Gaining knowledge on bees is crucial due to their important role in angiosperm pollination. This study presents the first genome assembly of the Colletes collaris bee. Through sequencing data from different platforms, the researchers were able to predict the genome composition and identify gene families undergoing rapid evolution within Colletes.
GENOME BIOLOGY AND EVOLUTION
(2023)
Article
Pharmacology & Pharmacy
Daohui Wang, Fengying Liu, Weijie Yang, Yangyang Sun, Xiaoning Wang, Xin Sui, Jun Yang, Qian Wang, Wenhao Song, Minmin Zhang, Zhenyu Xiao, Tian Wang, Yongan Wang, Yuan Luo
Summary: Hypoxic environments at high altitudes have a significant impact on the long-term health of residents. This study reveals that meldonium can prevent hypoxia-induced lung injury by regulating glycolysis and alleviating oxidative stress through the activation of Nrf2.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Charles Pouchon, Frederic Boyer, Cristina Roquet, France Denoeud, Jerome Chave, Eric Coissac, Inger Greve Alsos, Sebastien Lavergne
Summary: Low-coverage whole genome shotgun sequencing is a cost-effective method for acquiring genomic data in nonmodel organisms. In this study, a pipeline called ORTHOSKIM is introduced, which captures targeted sequences from genomic and transcriptomic libraries without assembling whole organelle genomes. ORTHOSKIM successfully recovered cpDNA, mtDNA, and rDNA sequences in plant families Primulaceae and Ericaceae.
MOLECULAR ECOLOGY RESOURCES
(2022)
Article
Biochemistry & Molecular Biology
Weishan Zhao, Xialian Bu, Hong Zou, Wenxiang Li, Shangong Wu, Ming Li, Guitang Wang
Summary: In this study, the MRO genome of Cepedea longa was sequenced and analyzed. It was found to have a linear structure with large inverted repeat gene regions at both ends. Compared to other species, C. longa MRO genome had a higher G + C content and repeat sequences near the central region. Phylogenetic analysis showed that C. longa clustered with P. lacertae, indicating their close relationship.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Genetics & Heredity
Yiling Fei, Senlin Hou, Yongwu Zhou, Xiaoming Xue
Summary: In this study, the complete mitochondrial genome of the Black Drongo was obtained for the first time, revealing its closest genetic relationship to the Bronzed Drongo.
MITOCHONDRIAL DNA PART B-RESOURCES
(2021)
Review
Virology
Marawan A. Marawan, Abdulaziz Alouffi, Suleiman El Tokhy, Sara Badawy, Ihsanullah Shirani, Ali Dawood, Aizhen Guo, Mashal M. Almutairi, Fahdah Ayed Alshammari, Abdelfattah Selim
Summary: Bovine leukaemia virus (BLV) is closely related to human T-cell leukaemia virus types 1 and 2 and causes enzootic bovine leukosis (EBL) in cattle. Most infected cattle are asymptomatic, but the disease still causes major economic losses in the cattle industry. Effective control measures and early detection are crucial due to the lack of an effective vaccine against BLV.
Article
Genetics & Heredity
Xin Li, Liang Wang, Ding Yang
Summary: In this study, the mitochondrial genome of Ornithomya biloba was sequenced and annotated, providing the first representative for the genus Ornithomya. The phylogenetic analysis showed that the monophyly of Hippoboscidae was supported, and it was found to be a sister group of Streblidae. The monophyletic Hippoboscoidea clade was formed by the families Hippoboscidae and Streblidae.
MITOCHONDRIAL DNA PART B-RESOURCES
(2022)
Article
Genetics & Heredity
Huanqing Zhang, Yuehuan Dong, Guolei Sun, Qingqian Wang, Yuntao Dong, Huashan Dou, Qinguo Wei
Summary: Eyebrowed Thrush is a highly migratory bird with a mitochondrial genome structure consistent with species in the genus Turdus. The study enhances understanding of phylogeny and genetics in the Turdidae and Muscicapoidea families.
MITOCHONDRIAL DNA PART B-RESOURCES
(2021)
Article
Medicine, Research & Experimental
Lanlan Zhang, Jianlong Wu, Ziguan Zhu, Yuchen He, Renpeng Fang
Summary: Aging is a natural process characterized by physical decline and increased vulnerability to death. Despite efforts to understand and delay aging, limited progress has been made in the field of anti-aging. Recent studies have focused on the role of mitochondrial dysfunction in aging and related degenerative diseases, suggesting that restoring mitochondrial function can promote healthy aging. This paper provides an overview of mitochondrial changes during aging and summarizes advanced studies on mitochondrial therapies for degenerative diseases, offering novel directions for future research.
Article
Genetics & Heredity
Maheshkumar Prakash Patil, Jong-Oh Kim, Yong Bae Seo, Jiyoung Shin, Ji-Young Yang, Gun-Do Kim
Summary: This study analyzed the mitochondrial DNA of Petrale sole Eopsetta jordani and found significant differences with other species in the same family. The results provide valuable data for studying genetic diversity and evolution.
MITOCHONDRIAL DNA PART B-RESOURCES
(2022)
Article
Genetics & Heredity
Jong-Oh Kim, Seong Seok Choi, Yong Bae Seo, Jiyoung Shin, Ji-Young Yang, Gun-Do Kim
Summary: The study presents the complete mitogenome of the sea peach H.aurantium, providing important data and results for future research on the evolution of Halocynthia and the Pyuridae.
MITOCHONDRIAL DNA PART B-RESOURCES
(2021)
Article
Biotechnology & Applied Microbiology
Steven Kelly
Summary: The difference in per-cell copy number of organellar and nuclear genomes provides an energetic incentive for cells to either delete organellar genes or transfer them to the nuclear genome. The majority of transferred organellar genes show that the energy saved by nuclear transfer exceeds the costs incurred from importing the protein into the organelle. The net energy saved by endosymbiotic gene transfer can constitute a significant proportion of total cellular energy budgets, providing a selectable advantage to the cell.
Article
Genetics & Heredity
Maria Alice Silva Oliveira, Tomaz Nunes, Maria Aparecida Dos Santos, Danyelle Ferreira Gomes, Iara Costa, Brena Van-Lume, Sarah S. Marques Da Silva, Ronaldo Simao Oliveira, Marcelo F. Simon, Gaus S. A. Lima, Danilo Soares Gissi, Cicero Carlos de Souza Almeida, Gustavo Souza, Andre Marques
Summary: Allopolyploidy is a key driver of speciation in the genus Stylosanthes Sw., but can make species recognition and breeding efforts challenging. By analyzing high-throughput sequencing samples, researchers were able to identify organelle and nuclear genome signatures to trace the origin and parental genome recognition of allopolyploids, providing important insights into genome evolution in this genus. Shared and unique satellite repeats were particularly helpful in tracing allopolyploid origins, such as the StyloSat1 satellite in the Scabra complex, demonstrating the power of comparative genomics in understanding complex polyploid genomes.
FRONTIERS IN GENETICS
(2021)
Article
Respiratory System
Dianpeng Wang, Xiangli Yang, Yanfang Zhang, Dafeng Lin, Paimao Li, Zhiming Zhang, Xianqing Huang, Dayong Gu, Jacky Fong-Chuen Loo
JOURNAL OF THORACIC DISEASE
(2018)
Article
Public, Environmental & Occupational Health
Dianpeng Wang, Dafeng Lin, Peimao Li, Huimin Liu, Yanhua Yang, Zhimin Zhang, Qiuyue Kong, Yanfang Zhang, Xianqing Huang
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH
(2019)
Article
Multidisciplinary Sciences
Dafeng Lin, Dianpeng Wang, Peimao Li, Xiangli Yang, Wei Liu, Lu Huang, Zhimin Zhang, Yanfang Zhang, Wen Zhang, Naixing Zhang, Ming Zhang, Xianqing Huang
Summary: This study further analyzed the dynamic features of TCR repertoires in OMDT patients, revealing significant differences in TRBV6-4 and TRBV7-9 frequencies between cases and controls. TCR combinations and sequences associated with the severity of OMDT were identified as potential therapeutic targets.
SCIENTIFIC REPORTS
(2021)