Article
Engineering, Electrical & Electronic
Yasmin Mustapha Kamil, Muhammad Hafiz Abu Bakar, Sura Hmoud Al-Rekabi, Mohd Hanif Yaacob, Amir Syahir, Mohd Adzir Mahdi
Summary: The study introduced a PAMAM-GO integrated microfiber sensor to detect Dengue virus II E protein, achieving higher sensitivity. By reducing the optical fiber diameter, this sensor can achieve better detection performance and potentially enhance the diagnostic capability for dengue fever.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2021)
Article
Chemistry, Analytical
Abeer Al Ghamdi, Benjamin Dawson, Gin Jose, Almut Beige
Summary: One way to monitor molecule concentrations optically is to utilize the high sensitivity of the transmission and reflection rates of Fabry-Perot cavities to changes in their optical properties. Fabry-Perot cavities can be used to non-invasively and remotely monitor molecule concentrations by reflecting light from the target molecules back into the cavity, which adds peaks to the overall reflection rate. An array of optical cavities can be used to probe a wide range of frequencies and obtain a unique optical fingerprint.
Article
Engineering, Electrical & Electronic
Xue Zhou, Shankun Wang, Xuegang Li, Yong Zhao, Yanan Zhang, Linh Viet Nguyen, Stephen C. Warren-Smith
Summary: This paper proposes a novel optical fiber sensor using exposed-core fiber (ECF) to excite whispering gallery modes (WGMs) within a high refractive index barium titanate glass microsphere for achieving label-free real-time specific DNA detection. The microsphere is encapsulated into the exposed channel of the ECF, allowing for physical stability while excited WGMs via the evanescent field. The sensor shows promising results in aqueous environment with high Q-factor levels and potential applications in disease diagnostics, chemical analysis, and environmental protection.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Hyeuk Jin Han, Seunghee H. Cho, Sangjun Han, Ji-Soo Jang, Gyu Rac Lee, Eugene N. Cho, Sang-Joon Kim, Il-Doo Kim, Min Seok Jang, Harry L. Tuller, Judy J. Cha, Yeon Sik Jung
Summary: A label-free, chemo-resistive/SERS multimodal sensor based on 3D-CMA has been introduced, showing strong enhancements in both chemo-resistive and SERS sensing characteristics. This sensor can selectively and quantitatively estimate mixed-gas compositions, even for mixtures with very similar molecular structures, by combining chemo-resistive and SERS multimodal sensing.
ADVANCED MATERIALS
(2021)
Article
Engineering, Electrical & Electronic
Xiaodong Fan, Zhonghua Ou, Lixun Zhang, Ruiming Zhang, Chenzhi Yuan, Guangwei Deng, You Wang, Haizhi Song, Lixing You, Yong Liu, Guangcan Guo, Qiang Zhou
Summary: In this paper, a dense temporal multiplexed FBG sensing scheme with single-photon detection is proposed and demonstrated. The experimental results show that using the dual-wavelength differential detection method can achieve high wavelength resolution and corresponding temperature resolution.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2022)
Article
Engineering, Electrical & Electronic
Chenxu Lu, Xiaopeng Dong, Chi Wu
Summary: This article proposes a novel detection scheme that measures temperature through the detection of a unique and easily identifiable critical wavelength (CWL) in a modified Vernier envelope. The Vernier envelope is created by cascading two existing single-mode fiber (SMF)-few-mode fiber (FMF)-SMF (SFS) structures with a varying free spectrum range (FSR) at the CWL. Experimental and simulation results show that the CWL in the Vernier envelope shifts monotonically with temperature, and the sensitivity is improved compared to a single SFS structure.
IEEE SENSORS JOURNAL
(2023)
Review
Chemistry, Multidisciplinary
Wenjing Liu, You-Ling Chen, Shui-Jing Tang, Frank Vollmer, Yun-Feng Xiao
Summary: Optical microresonators have been widely studied for highly sensitive molecular detection and optical precision measurement. The combination of high quality factor and small mode volume in whispering-gallery mode microresonators enhances nonlinear light-matter interaction, enabling label-free molecule detection with ultrahigh sensitivity and specific spectral fingerprinting of molecules. These nonlinear optical sensors show promise for future research and applications in sensing technologies.
Article
Chemistry, Analytical
Yuyuan Xie, Maoning Wang, Yuzhong Zhong, Lin Deng, Jianwei Zhang
Summary: Deep learning anomaly detection is crucial in distributed optical fiber acoustic sensing (DAS). To overcome the challenges posed by scarcity of true-positive data and imbalance and irregularity within datasets, an unsupervised deep learning method is proposed, which learns only the normal data features to detect anomalies.
Article
Chemistry, Analytical
Swati Mohanty, Gajendranath Chowdary, Shiv Govind Singh
Summary: This paper presents a portable, label-free chemiresistive sensor for the selective detection of lead (Pb) ions in water. The sensor exhibits high selectivity and can be analyzed quickly using a smartphone interface. The results show that the sensor can successfully detect the presence of lead ions even at a concentration as low as 100 pico Molar (pM). In addition, a machine learning algorithm is used to enhance data analysis and assist in classification.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Debadrita Paria, Kam Sang Kwok, Piyush Raj, Peng Zheng, David H. Gracias, Ishan Barman
Summary: The study reports a large-scale and label-free testing platform that combines surface-enhanced Raman spectroscopy and machine learning for rapid and accurate detection of SARS-CoV-2. The technique can not only distinguish between different types of viruses, but also detect virus signatures in human saliva without additional sample preparation.
Article
Chemistry, Analytical
Meixing Li, Juan Cheng, Haitao Zheng, Jiawei Shi, Qingming Shen
Summary: A new electrochemical sensing strategy was developed for the precise detection of ultra-low abundance microRNA-21. The sensor utilized modified magnetic beads and hybridization chain reaction (HCR) to achieve signal amplification while avoiding modification fluctuation. The biosensor exhibited excellent specificity and reproducibility in complex sample analysis.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Guang Liu, Yaru Li, Yanli Lu, Yixuan Jia, Jianzhen Shan, Qingjun Liu
Summary: This study proposes a label-free cysteine sensor based on smartphone technology, which can be used for point-of-care testing. The sensor system shows high linearity correlation and low detection limit for cysteine. It provides an effective and portable method for cysteine detection.
Article
Chemistry, Multidisciplinary
Ye Luo, Chunlei Sun, Maoliang Wei, Hui Ma, Yingchun Wu, Zequn Chen, Hao Dai, Jialing Jian, Boshu Sun, Chuyu Zhong, Junying Li, Kathleen A. Richardson, Hongtao Lin, Lan Li
Summary: Photonic mechanical sensors offer advantages over electronic counterparts, but existing flexible photonics strategies face challenges. To address these, a waveguide-integrated flexible mechanical sensor based on photonic crystal microcavities is proposed, with exceptional performance and potential applications.
Article
Engineering, Electrical & Electronic
Jixuan Wu, Qian Wang, Binbin Song, Cheng Zhang
Summary: This paper proposes and demonstrates a side-hole MOF integrative twin-microchannels for optofluidic sensing application. The structure allows long interaction path-length between light and analyte samples, achieving high sensitive sensing in the low refractive index range. The microfluidic approach enables the loading of fluid liquids into the MOF's cross-sectional air holes for light-matter interaction study.
IEEE SENSORS JOURNAL
(2022)
Article
Biophysics
Yuanyuan Guo, Carl Frederik Werner, Shoma Handa, Mengyun Wang, Tomokazu Ohshiro, Hajime Mushiake, Tatsuo Yoshinobu
Summary: This study developed an all-in-one pH probe for spatially-resolved and label-free pH sensing in vivo, integrating a field-effect pH sensor with a multimodal fiber. The probe can measure pH changes at multiple spots simultaneously with high spatial and temporal resolutions, and has been successfully implanted into the hippocampal formation of rats for pH measurement under physiological and pathological conditions.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Physical
Yuhan Wang, Dianhong Wang, Xiangli Zhang, Tianye Huang, Xiang Zhao, Shuwen Zeng
Summary: By introducing sub-wavelength grating (SWG) waveguide in the long-range surface phonon resonance (LRSPhR) device, a mid-infrared Fano resonance is formed, offering improved sensing performance. The index sensitivity and figure of merit of the sensor reach 7496 RIU-1 and 46,432 respectively, which is 6 times higher compared to conventional waveguide-coupled LRSPhR. The proposed SWG-coupled Fano resonance serves as a promising platform for mid-infrared biochemical sensing.
Review
Nanoscience & Nanotechnology
Shuyan Zhang, Chi Lok Wong, Shuwen Zeng, Renzhe Bi, Kolvyn Tai, Kishan Dholakia, Malini Olivo
Summary: Metasurfaces, as a cutting-edge nanophotonics concept, have demonstrated great potential in biomedical engineering for various bioimaging and biosensing applications. This review article covers the state of the art of metasurface technology in biomedical applications and provides insights into both challenges and opportunities in this field.
Article
Materials Science, Multidisciplinary
Yinghao Xu, Kui Lai, Chenjie Gu, Tao Jiang, Xiang Shen, Shuwen Zeng, Aaron Ho-Pui Ho, Diing Shenp Ang, Jun Zhou
Summary: A novel electrically programmable SERS substrate is prepared using MoOx/Ag hybrids deposited within electrodes, allowing for control of Ag nanoparticle size and Raman enhancement factors by adjusting the leakage current level. The maximum detection limit achieved on the 10(-3) A substrate is 10(-8) m.
PHYSICA STATUS SOLIDI-RAPID RESEARCH LETTERS
(2021)
Article
Crystallography
Lina Jaya Diguna, Aprilia Dyah Fitriani, Beta Riana Liasari, Gerald Ensang Timuda, Wahyu Bambang Widayatno, Agus Sukarto Wismogroho, Shuwen Zeng, Muhammad Danang Birowosuto, Muhamad Ikhlasul Amal
Summary: This study successfully synthesized zinc oxide nanoparticles using acetic acid as a leaching agent via hydrometallurgical method from zinc dross, followed by adsorption of dye molecules onto the nanoparticles film. Optical absorption and photoluminescence confirmed the photosensitization and emission properties of the zinc oxide nanoparticles with dye. Enhanced current density in photodetection characterization under simulated solar illumination suggests potential recycling of zinc dross into valuable zinc oxide nanoparticles for sensing applications in the visible light region.
Article
Chemistry, Physical
Zakariae Oumekloul, Shuwen Zeng, Younes Achaoui, Abdellah Mir, Abdellatif Akjouj
Summary: The biggest challenge in smart city technology is providing autonomous energy, with metamaterials serving as an important research area for creating unique properties and functions. By combining simple layered surfaces and appropriate material selection, new types of solar cells can be manufactured to work across a wide frequency range.
Article
Nanoscience & Nanotechnology
Yuye Wang, Shuwen Zeng, Aurelian Crunteanu, Zhenming Xie, Georges Humbert, Libo Ma, Yuanyuan Wei, Aude Brunel, Barbara Bessette, Jean-Christophe Orlianges, Fabrice Lalloue, Oliver G. Schmidt, Nanfang Yu, Ho-Pui Ho
Summary: An enhanced plasmonic biosensor was developed in this study to detect small cancer biomarkers with low molecular weight and low concentration range. By precisely engineering atomically thin materials, a phase singularity and significant lateral position shift effect were achieved, enabling the detection of TNF-alpha cancer marker at the femtomolar level.
NANO-MICRO LETTERS
(2021)
Article
Chemistry, Analytical
Manel Hedhly, Yuye Wang, Shuwen Zeng, Faouzi Ouerghi, Jun Zhou, Georges Humbert
Summary: The study presents a highly sensitive plasmonic biosensor based on a symmetric metal cladding plasmonic waveguide structure for the detection of low concentration small molecules. By precise design and tuning of the guiding layer, ultra-high order modes can be excited, leading to steep phase change and large position shift for the detection of biomolecules that are difficult to detect using traditional SPR techniques.
Article
Chemistry, Analytical
Joelle Youssef, Shaodi Zhu, Aurelian Crunteanu, Jean-Christophe Orlianges, Ho-Pui Ho, Renaud Bachelot, Shuwen Zeng
Summary: In this paper, a plasmonic metasensor with a phase-change material as the sensing layer is demonstrated to detect ultra-low refractive index changes. The high sensitivity and direct measurement of the phase-related lateral position shift make it a feasible method for detecting cancer biomarkers.
Article
Chemistry, Analytical
Nurzad Zakirov, Shaodi Zhu, Aurelien Bruyant, Gilles Lerondel, Renaud Bachelot, Shuwen Zeng
Summary: In this study, structures based on copper nanosubstrate with graphene and two-dimensional transition metal dichalcogenides (TMDC) were designed to achieve an ultrasensitive surface plasmon resonance biosensor. Theoretical calculations showed an enhanced sensitivity with a detection limit of 10^(-9) refractive index unit (RIU) by optimizing the parameters of the SPR sensing substrate.
Article
Chemistry, Multidisciplinary
Fusheng Du, Kai Zheng, Shuwen Zeng, Yufeng Yuan
Summary: This study provides a theoretical insight into the design of novel plasmonic biosensors using bismuth selenide (Bi2Se3)-Graphene heterostructures. By varying the thickness of the heterostructures, significant sensitivity enhancement is achieved, and the biosensor shows potential for monitoring virus samples.
Article
Chemistry, Multidisciplinary
Hicham Mangach, Youssef El Badri, Abdelhamid Hmima, Abdenbi Bouzid, Younes Achaoui, Shuwen Zeng
Summary: The exploration of engineered materials' propensity to bring forward innovations based on their periodic nanostructured tailoring has propelled optical sensors to the forefront of ultra-sensitive bio-identification. Numerical analysis based on the Finite Element Method (FEM) was used to investigate and optimize the optical properties of a unidirectional asymmetric dimer photonic crystal. The proposed optical sensor demonstrated promising prospects for monitoring the DNA hybridization process with a high quality factor and detection limit.
Article
Chemistry, Analytical
Nour Beydoun, Yann Niberon, Laurent Arnaud, Julien Proust, Komla Nomenyo, Shuwen Zeng, Gilles Lerondel, Aurelien Bruyant
Summary: This research demonstrates that applying a thin layer of aluminum oxide to copper films can effectively slow down the oxidation rate. This simple method could provide a new approach for producing alternative and more sustainable biochips.
Article
Chemistry, Analytical
Shaodi Zhu, Zhenming Xie, Yuzhi Chen, Shiyue Liu, Yiu-Wa Kwan, Shuwen Zeng, Wu Yuan, Ho-Pui Ho
Summary: In this study, a surface plasmon resonance (SPR) fiber probe that can work intravenously is proposed for real-time detection of circulating tumor cells (CTCs) in blood. The continuous capture of CTCs enhances enrichment and improves enumeration accuracy. The plasmonic fiber probe demonstrates specific detection of breast cancer cells in flowing blood and has potential for clinical use in detecting low concentration biomarkers in circulating blood.
Review
Materials Science, Multidisciplinary
Arie Wibowo, Md Abdul Kuddus Sheikh, Lina Jaya Diguna, Muhammad Bagas Ananda, Maradhana Agung Marsudi, Arramel Arramel, Shuwen Zeng, Liang Jie Wong, Muhammad Danang Birowosuto
Summary: This Review discusses recent advances and strategies to improve the light yield, decay time, and coincidence timing resolution of all-inorganic and hybrid organic-inorganic perovskite scintillators. Inorganic scintillators play a major role in ionizing radiation detection and have various applications in medical imaging, homeland security, high-energy physics, industrial control, oil drilling explorations, and energy management.
COMMUNICATIONS MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Fusheng Du, Kai Zheng, Shuwen Zeng, Yufeng Yuan
Summary: This study presents a new design for a tunable plasmonic biosensor using a twisted bilayer graphene (TBG) superlattice and a plasmonic gold thin film. The biosensor can achieve ultrasensitive biosensing through modulation of the Goos-Hanchen (GH) shift. The optimized configuration of the biosensor demonstrates a theoretical possibility for quantitative monitoring of SARS-CoV-2 and human hemoglobin, showing potential for biomedical applications.
