The DNA methylation of FOXO3 and TP53 as a blood biomarker of late-onset asthma

SIRT1 inhibits chemoresistance and cancer stemness of gastric cancer by initiating an AMPK/FOXO3 positive feedback loop

(2020) Yifei An et al.   Cell Death & Disease

DNA methylation down‐regulates integrin β4 expression in asthmatic airway epithelial cells

(2020) Mengping Wu et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Deducting MicroRNA-Mediated Changes Common in Bronchial Epithelial Cells of Asthma and Chronic Obstructive Pulmonary Disease—A Next-Generation Sequencing-Guided Bioinformatic Approach

(2019) Ming-Ju Tsai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cellular Senescence: The Trojan Horse in Chronic Lung Diseases

(2019) Shruthi Hamsanathan et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Phenotypes and endotypes of adult asthma: Moving toward precision medicine

(2019) Ravdeep Kaur et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The nasal methylome as a biomarker of asthma and airway inflammation in children

(2019) Andres Cardenas et al.   Nature Communications

Particulate matter exposure shapes DNA methylation through the lifespan

(2019) L. Ferrari et al.   Clinical Epigenetics

Age-related lung tissue remodeling due to the local distribution of MMP-2, TIMP-2, TGF-β and Hsp70

(2018) Z Vitenberga et al.   BIOTECHNIC & HISTOCHEMISTRY

ITGB4 is essential for containing HDM-induced airway inflammation and airway hyperresponsiveness

(2018) Chi Liu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Functions and mechanisms of epigenetic inheritance in animals

(2018) Ksenia Skvortsova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The role of DNA methylation in epigenetics of aging

(2018) Archana Unnikrishnan et al.   PHARMACOLOGY & THERAPEUTICS

DNA methylation protects against cisplatin-induced kidney injury by regulating specific genes, including interferon regulatory factor 8

(2017) Chunyuan Guo et al.   KIDNEY INTERNATIONAL

LncRNA-mediated SIRT1/FoxO3a and SIRT1/p53 signaling pathways regulate type II alveolar epithelial cell senescence in patients with chronic obstructive pulmonary disease

(2017) Chao Gu et al.   Molecular Medicine Reports

The interaction between farming/rural environment and TLR2, TLR4, TLR6 and CD14 genetic polymorphisms in relation to early- and late-onset asthma

(2017) Melisa Y. Z. Lau et al.   Scientific Reports

Familial Hypercholesterolemia Phenotype in Chinese Patients Undergoing Coronary AngiographyHighlights

(2016) Jian-Jun Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Staphylococcal enterotoxin IgE sensitization in late-onset severe eosinophilic asthma in the elderly

(2016) W.-J. Song et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Early Detection of Lung Cancer Using DNA Promoter Hypermethylation in Plasma and Sputum

(2016) Alicia Hulbert et al.   CLINICAL CANCER RESEARCH

DNA methylation perspectives in the pathogenesis of autoimmune diseases

(2016) Bao Sun et al.   CLINICAL IMMUNOLOGY

Resveratrol induces cell cycle arrest and apoptosis in human eosinophils from asthmatic individuals

(2016) Xin Hu et al.   Molecular Medicine Reports

BRCA1 positively regulates FOXO3 expression by restricting FOXO3 gene methylation and epigenetic silencing through targeting EZH2 in breast cancer

(2016) C Gong et al.   Oncogenesis

Epidemiology of Chronic Obstructive Pulmonary Disease (COPD) in Aging Populations

(2015) Carlos A. Vaz Fragoso   COPD-Journal of Chronic Obstructive Pulmonary Disease

A positive feedback loop of p53/miR-19/TP53INP1 modulates pancreatic cancer cell proliferation and apoptosis

(2015) XIAOFANG WANG et al.   ONCOLOGY REPORTS

Peripheral whole blood FOXP3 TSDR methylation: a potential marker in severity assessment of autoimmune diseases and chronic infections

(2014) Owen Ngalamika et al.   IMMUNOLOGICAL INVESTIGATIONS

FOXO3 and Related Transcription Factors in Development, Aging, and Exceptional Longevity

(2014) A. J. Kahn   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The role of bronchial epithelial cell apoptosis in the pathogenesis of COPD

(2014) B. Gogebakan et al.   MOLECULAR BIOLOGY REPORTS

DNA methylation of BDNF as a biomarker of early-life adversity

(2014) Marija Kundakovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p53 Codon 72 Genetic Polymorphism in Asthmatic Children: Evidence of Interaction With Acid Phosphatase Locus 1

(2014) Patrizia Saccucci et al.   Allergy Asthma & Immunology Research

Pathogenesis of severe asthma

(2012) A. H. Poon et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Downregulation of Integrin β4 Decreases the Ability of Airway Epithelial Cells to Present Antigens

(2012) Chi Liu et al.   PLoS One

FOXO3 Is a Glucocorticoid Receptor Target and Regulates LKB1 and Its Own Expression Based on Cellular AMP Levels via a Positive Autoregulatory Loop

(2012) Nicolas Lützner et al.   PLoS One

Demethylation of the FCER1G promoter leads to FcεRI overexpression on monocytes of patients with atopic dermatitis

(2011) Y. Liang et al.   ALLERGY

Asthma in the elderly: Current understanding and future research needs—a report of a National Institute on Aging (NIA) workshop

(2011) Nicola A. Hanania et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

FOXO3 Deficiency Leads to Increased Susceptibility to Cigarette Smoke-Induced Inflammation, Airspace Enlargement, and Chronic Obstructive Pulmonary Disease

(2011) J.-w. Hwang et al.   JOURNAL OF IMMUNOLOGY

DNA Methylation of the First Exon Is Tightly Linked to Transcriptional Silencing

(2011) Fabienne Brenet et al.   PLoS One

Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data

(2010) Mette Soerensen et al.   AGING CELL

FoxO3a involved in neutrophil and T cell survival is overexpressed in rheumatoid blood and synovial tissue

(2009) F. Turrel-Davin et al.   ANNALS OF THE RHEUMATIC DISEASES

COPD as a Disease of Accelerated Lung Aging

(2009) Kazuhiro Ito et al.   CHEST

Environmental Epigenetics and Asthma

(2008) Rachel L. Miller et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Global strategy for asthma management and prevention: GINA executive summary

(2008) E. D. Bateman et al.   EUROPEAN RESPIRATORY JOURNAL

FOXO3A genotype is strongly associated with human longevity

(2008) B. J. Willcox et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA