Article
Radiology, Nuclear Medicine & Medical Imaging
Xiaohong Han, Luchen Chang, Ke Song, Longlong Cheng, Minghui Li, Xi Wei
Summary: In this study, a multitask network based on TI-RADS (MTN-TI-RADS) was proposed for the classification of thyroid nodules. This network obtains a set of TI-RADS classifications of nodules through multitask learning, calculates the TI-RADS points and risk levels, and finally classifies nodules as benign or malignant. The classification process of the network is consistent with the diagnostic process of physicians, making the results easily interpretable. Attention modules are also introduced to focus on critical features. The results showed that MTN-TI-RADS outperformed senior radiologists in classifying malignant and benign thyroid nodules.
Article
Radiology, Nuclear Medicine & Medical Imaging
Ting-Yue Qi, Xiao Chen, Hua Liu, Lun Mao, Jian Chen, Bei-Li He, Wei-Bing Zhang
Summary: This study compared the differences among ACR TI-RADS, Kwak TI-RADS, and ATA guidelines in terms of specificity, sensitivity, and unnecessary FNA rate. It also observed how the recommended FNA nodule size threshold affected the results. The UFRs of FNA recommended by Kwak TI-RADS and ATA guidelines were higher than that of ACR TI-RADS, and were influenced by the recommended FNA nodule size threshold.
EUROPEAN JOURNAL OF RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ying Liu, Xiaoxian Li, Cuiju Yan, Longzhong Liu, Ying Liao, Hongyan Zeng, Weijun Huang, Qian Li, Nansheng Tao, Jianhua Zhou
Summary: The study aimed to investigate whether artificial intelligence-based modification of the Thyroid Imaging Reporting Data System (TI-RADS) would be superior to the current American College of Radiology (ACR) TI-RADS in risk stratification of thyroid nodules. The results showed that AI TI-RADS could reduce the number of benign nodules recommended for biopsy and improve specificity compared to ACR TI-RADS.
EUROPEAN RADIOLOGY
(2022)
Article
Oncology
Zhiguang Chen, Yue Du, Linggang Cheng, Yukang Zhang, Shuai Zheng, Rui Li, Wenkai Zhang, Wei Zhang, Wen He
Summary: This study proposed a new thyroid imaging reporting and data system (sTI-RADS) and compared it with the existing TI-RADS. The results showed that sTI-RADS had higher accuracy and specificity in distinguishing benign and malignant thyroid nodules. The inter- and intra-group consistency of grading by five ultrasound physicians also indicated the reliability of sTI-RADS.
Article
Oncology
Wenwu Lu, Di Zhang, Yuzhi Zhang, Xiaoqin Qian, Cheng Qian, Yan Wei, Zicong Xia, Wenbo Ding, Xuejun Ni
Summary: This study developed a predictive model using ultrasound radiomics and clinical data to assess the benign or malignant nature of thyroid nodules smaller than 1 cm. The results showed that the model had high diagnostic capability and clinical application value.
Article
Radiology, Nuclear Medicine & Medical Imaging
Kelly E. Daniels, Jiajun Xu, Ji-Bin Liu, Xiangmei Chen, Kun Huang, Jena Patel, Elizabeth Cottrill, John R. Eisenbrey, Andrej Lyshchik
Summary: The study found that the ACR TI-RADS classification system exhibits low inter-reader and intra-reader reliability when assessing the genetic risk of nodules with indeterminate cytology.
ACADEMIC RADIOLOGY
(2021)
Article
Oncology
Menghui Li, Lijuan Wei, Fangxuan Li, Yanyan Kan, Xiaofeng Liang, Huan Zhang, Juntian Liu
Summary: The study demonstrated the importance of the modified TI-RADS report system in distinguishing malignant and benign thyroid nodules, especially in managing high-risk nodules. Changes in nodule grade status were mainly observed in grades 4a and above over a 5-year follow-up period, with higher grades indicating more malignant progression.
CANCER MANAGEMENT AND RESEARCH
(2021)
Article
Chemistry, Analytical
Alisa Kunapinun, Dittapong Songsaeng, Sittaya Buathong, Matthew N. Dailey, Chadaporn Keatmanee, Mongkol Ekpanyapong
Summary: A thyroid nodule, a common abnormal growth in the thyroid gland, can be identified through ultrasound imaging. The Thyroid Imaging Reporting and Data System (TI-RADS) categorizes nodules into risk levels, guiding further evaluation. Machine learning improves the detection accuracy of TI-RADS by complementing its classification methods. This paper presents an automated system using ResNet-101 and DenseNet-201 models to classify thyroid nodules according to TI-RADS and malignancy.
Article
Engineering, Biomedical
Jingqi Zhang, Qingsong Wang, Jingwen Zhao, Hui Yu, Fei Wang, Jie Zhang
Summary: The aim of this study was to implement automatic risk level assessment of thyroid nodules. An improved U-Net++ model was used for segmenting thyroid nodules in ultrasound images, and a multi-task convolutional neural network (MT-CNN) based on KWAK TI-RADS was employed for risk level calculation. The proposed CAD method showed favorable performance in the diagnosis of thyroid nodules.
PHYSICS IN MEDICINE AND BIOLOGY
(2023)
Article
Oncology
Ge-Ge Wu, Wen-Zhi Lv, Rui Yin, Jian-Wei Xu, Yu-Jing Yan, Rui-Xue Chen, Jia-Yu Wang, Bo Zhang, Xin-Wu Cui, Christoph F. Dietrich
Summary: This study showed that deep learning could improve the differentiation between malignant and benign thyroid nodules, with significant clinical potential on TR4 and TR5 categories. The DL algorithm achieved better sensitivity and specificity compared to radiologists in the independent test set.
FRONTIERS IN ONCOLOGY
(2021)
Article
Otorhinolaryngology
William Thedinger, Easwer Raman, Jagdish K. Dhingra
Summary: In a community setting, the adoption rate of the ACR TI-RADS scoring system has gradually increased over a 3-year period, although the ATA 2015 risk scoring system performed better.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2022)
Article
Oncology
Lydia Elbatarny, Richard K. G. Do, Natalie Gangai, Firas Ahmed, Shalini Chhabra, Amber L. Simpson
Summary: The lack of standardization among radiologists in writing radiological reports impacts the ability to interpret cancer response to treatment at a large scale. This study examines the utility of applying natural language processing (NLP) to the large-scale interpretation of disease responses using a standardized oncologic response lexicon (OR-RADS) to facilitate real world evidence (RWE) collection. The study demonstrates the feasibility of using NLP to predict disease response in cancer patients, surpassing human performance, and encourages the use of standardized OR-RADS categories to improve large-scale prediction accuracy.
Article
Engineering, Biomedical
Ping Yu, Sihua Niu, Shuang Gao, Hui Tian, Jiaan Zhu
Summary: The use of contrast-enhanced ultrasonography (CEUS) can improve the diagnosis of benign and malignant thyroid nodules classified as TI-RADS 4 or 5. CEUS provides valuable supplementary information and quantitative analysis for clinical applications.
APPLIED BIONICS AND BIOMECHANICS
(2022)
Article
Medicine, General & Internal
Lijun Hao, Peiqing Liu, Changwei Ding, Jing Li, Yingchun Zhang
Summary: The study aimed to assess the diagnostic value of American College of Radiology (ACR) thyroid imaging reporting and data system (TI-RADS) combined with three-dimensional shear wave elastography (3D-SWE) in ACR TI-RADS 4 and 5 thyroid nodules. The results showed that combined ACR TI-RADS has higher diagnostic efficiency than conventional ACR TI-RADS, with significant improvements in sensitivity and accuracy. It can be used as an effective method in the diagnosis of thyroid nodules.
CHINESE MEDICAL JOURNAL
(2023)
Article
Health Care Sciences & Services
Yung-Chun Chang, Yan-Chun Hsing, Yu-Wen Chiu, Cho-Chiang Shih, Jun-Hong Lin, Shih-Hsin Hsiao, Koji Sakai, Kai-Hsiung Ko, Cheng-Yu Chen
Summary: In this research, a multi-objective deep learning model called CT2Rep was proposed for generating lung radiology reports by extracting semantic features from lung CT scans. The CT2Rep achieved remarkable performance in predicting important indicators of lung cancer, with an F-1-score of 87.29%. The results demonstrate the great potential of this model for reliable and robust quantitative lung diagnosis reports.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Review
Surgery
Joseph R. Imbus, Corrine I. Voils, Luke M. Funk
SURGERY FOR OBESITY AND RELATED DISEASES
(2018)
Editorial Material
Surgery
Joseph R. Imbus, Luke M. Funk
Article
Surgery
Nick A. Zaborek, Andy Cheng, Joseph R. Imbus, Kristin L. Long, Susan C. Pitt, Rebecca S. Sippel, David F. Schneider
Article
Education, Scientific Disciplines
Priya H. Dedhia, Meredith Barrett, Graham Ives, Christopher P. Magas, Oliver A. Varban, Sandra L. Wong, Gurjit Sandhu
JOURNAL OF SURGICAL EDUCATION
(2019)
Article
Surgery
Tenzin S. Atruktsang, Nick A. Zaborek, Joseph R. Imbus, Kristin Long, Susan C. Pitt, Rebecca S. Sippel, David F. Schneider
JOURNAL OF SURGICAL RESEARCH
(2019)
Article
Surgery
Kevin C. Janek, Kyla M. Bennett, Joseph R. Imbus, Juan S. Danobeitia, Jennifer L. Philip, David M. Melnick
JOURNAL OF VASCULAR SURGERY
(2020)
Article
Oncology
Priya H. Dedhia, Elizabeth M. Stoeckl, Alexandria D. McDow, Susan C. Pitt, David F. Schneider, Rebecca S. Sippel, Kristin L. Long
JOURNAL OF SURGICAL ONCOLOGY
(2020)
Article
Medicine, Research & Experimental
Ki-Suk Kim, Bailey Ce Peck, Yu-Han Hung, Kieran Koch-Laskowski, Landon Wood, Priya H. Dedhia, Jason R. Spence, Randy J. Seeley, Praveen Sethupathy, Darleen A. Sandoval
Summary: This study found that vertical sleeve gastrectomy (VSG) increases the number of hormone-secreting enteroendocrine cells (EECs) in the intestine through bile acid signaling, which drives intestinal stem cell fate towards EEC differentiation.
Article
Surgery
Sang Min Lee, Priya H. Dedhia, Chengli Shen, John E. Phay
Summary: This study found that near-infrared autofluorescence intensity in patients with primary hyperparathyroidism correlated with parathyroid gland weight and patient age. This suggests that the use of near-infrared cameras may be particularly helpful in identifying smaller adenomas and in older patients.
Article
Orthopedics
Ryan Furdock, Andy J. Kuo, Kallie W. Chen, Raymond Liu
Summary: This study evaluated the applicability of three upper extremity skeletal maturity systems in modern pediatric populations. The results showed that there were some discrepancies in skeletal age estimates depending on the race and sex of the patient.
JOURNAL OF PEDIATRIC ORTHOPAEDICS
(2023)
Article
Multidisciplinary Sciences
Priya H. Dedhia, Hemamylammal Sivakumar, Marco A. Rodriguez, Kylie G. Nairon, Joshua M. Zent, Xuguang Zheng, Katie Jones, Liudmila V. Popova, Jennifer L. Leight, Aleksander Skardal
Summary: Adrenocortical carcinoma (ACC) has a poor prognosis due to a lack of new drugs, which is partly attributed to the absence of suitable preclinical models. In this study, a 3D tumor construct platform was successfully generated from an established ACC cell line. The platform showed expression of biomarkers associated with ACC and demonstrated decreased drug sensitivity compared to 2D cell culture. This work represents the first evidence of a 3D tumor constructs platform for ACC, which can be utilized for mechanistic studies and the development of new intervention and therapy targets.
SCIENTIFIC REPORTS
(2023)
Article
Surgery
Vikrom K. Dhar, Nipun B. Merchant, Sameer H. Patel, Michael J. Edwards, Koffi Wima, Joseph Imbus, Daniel E. Abbott, Sharon M. Weber, Raphael Louie, Hong J. Kim, Robert C. G. Martin, Charles R. Scoggins, David J. Bentrem, Michael T. LeCompte, Kamran Idrees, Alexandra G. Lopez-Aguiar, Shishir K. Maithel, David A. Kooby, Daniel A. Franco, Danny Yakoub, Syed A. Ahmad
Editorial Material
Surgery
Meghal Shah, Tejas S. Sathe, Sukriti Bansal, Anai N. Kothari, Sophie Dream
JOURNAL OF SURGICAL RESEARCH
(2024)
Letter
Surgery
Zafer Turkyilmaz, Ramazan Karabulut, Kaan Sonmez
JOURNAL OF SURGICAL RESEARCH
(2024)
Letter
Surgery
Priyanka Jadhav, Gerald Gollin
JOURNAL OF SURGICAL RESEARCH
(2024)
Review
Surgery
Kheira Hireche, Ludovic Canaud, Pierre Antoine Peyron, Linda Sakhri, Isabelle Serres, Sanaa Kamel, Youcef Lounes, Thomas Gandet, Pierre Alric
Summary: This study evaluated the elastic properties of commonly used vascular substitutes for pulmonary artery replacement and compared their compliance and stiffness indexes to human pulmonary artery. The results showed that allogenic arterial grafts appeared to be the most suitable vascular substitutes in terms of compliance and stiffness for PA replacement.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Margaret Siu, Aixa Perez Coulter, Heather M. Grant, Reginald Alouidor, Michael Tirabassi
Summary: There is no significant difference in adverse respiratory events between intubated, critically ill patients requiring operative intervention who are kept NPO for 6 hours or longer compared to those kept NPO for less than 6 hours. Patients commonly experience periods of fasting much longer than the recommended 6-hour period by the American Society of Anesthesiologists.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Whitney Elks, Allison G. McNickle, Matthew Kelecy, Kavita Batra, Shirley Wong, Shawn Wang, Lisa Angotti, Deborah A. Kuhls, Charles St Hill, Syed F. Saquib, Paul J. Chestovich, Douglas R. Fraser
Summary: This study aimed to compare the effects of early and late enteral feeding after PEG placement on achieving nutritional therapy goals and adverse outcomes. The results showed that patients with early initiation of feeds achieved a higher percentage of goals on day 0 without an increased rate of adverse events.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Manisha B. Bhatia, Cassandra M. Anderson, Abdiwahab N. Hussein, Brian Opondo, Nereah Aruwa, Otieno Okumu, Sarah G. Fisher, Tasha Sparks Joplin, JoAnna L. Hunter-Squires, Brian W. Gray, Peter W. Saula
Summary: This study aimed to understand postoperative pediatric nutrition practices in Kenya and the United States. The results showed that in the United States, patients initiated enteral nutrition earlier and had shorter hospital stays. However, in Kenya, patients initiated enteral nutrition earlier but had no significant difference in hospital stays.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
David P. Stonko, Joseph Edwards, Hossam Abdou, Rebecca Treffalls, Patrick Walker, Jonathan J. Morrison
Summary: Raising mean arterial pressure (MAP) >90 mmHg with norepinephrine can increase gastroduodenal artery (GDA) flow and delay bowel ischemia.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
David R. Mann, Kathryn E. Engelhardt, Barry C. Gibney, Macelyn E. Batten, Eric C. Klipsch, Rupak Mukherjee, Ian C. Bostock
Summary: Pathologic upstaging is associated with decreased overall survival in cT1b esophageal cancer. Esophagectomy has better survival outcomes compared to endoscopic local tumor excision. Neoadjuvant chemoradiation therapy does not improve overall survival in cT1b lesions.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Ross Mudgway, Zachary Tran, Juan C. Quispe Espiritu, Woo Bin Bong, Hayden Schultz, Vamsi Vemireddy, Aarthy Kannappan, Marcos Michelotti, Kaushik Mukherjee, Jeffrey Quigley, Keith Scharf, Daniel Srikureja, Sharon S. Lum, Esther Wu
Summary: Comparison of medium-term outcomes between robotic-assisted cholecystectomy (RC) and laparoscopic cholecystectomy (LC) using validated quality of life (QoL) and pain assessments did not show significant differences.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Ningjie Chen, Haitao Wang, Yang Shao, Jincun Yang, Guodong Song
Summary: This study aimed to compare the therapeutic effects of activated platelet-rich plasma (PRP) prepared from elderly individuals and young adults in treating pressure ulcers (PUs). The results showed that PRP from young adults had higher platelet concentrations and greater production of growth factors, leading to better wound healing.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Brendin R. Beaulieu-Jones, Margaret T. Berrigan, Kortney A. Robinson, Jayson S. Marwaha, Tara S. Kent, Gabriel A. Brat
Summary: Introduction: Prescription opioids, including those prescribed after surgery, have greatly contributed to the US opioid epidemic. Educating opioid prescribers is a crucial component of ensuring the safe use of opioids among surgical patients. This study implemented an annual education curriculum for new surgical prescribers, resulting in significant improvements in knowledge and comfort levels. However, there remains a persistent knowledge and comfort gap among these prescribers.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Sneha G. Bhat, Madhuri Nagaraj, Courtney Balentine, Timothy Hogan, Jennie Meier, Hillary Prince, Kareem Abdelfattah, Herbert Zeh, Benjamin Levi
Summary: This pilot study examined the effects of a structured mental fitness program on academic surgeons and found significant improvement in Positive Intelligence (PQ) scores, as well as increased connectedness and shared language among participants. However, there were no significant changes in sleep, well-being, or teaching evaluations.
JOURNAL OF SURGICAL RESEARCH
(2024)
Article
Surgery
Kristin E. Cox, Michael A. Turner, Siamak Amirfakhri, Thinzar M. Lavin, Mojgan Hosseini, Pradipta Ghosh, Marygorret Obonyo, Takashi Murakami, Robert M. Hoffman, Paul J. Yazaki, Michael Bouvet
Summary: This study demonstrates the potential of using humanized anti-carcinoembryonic antigen (CEA) antibodies conjugated with near-infrared dyes to specifically label gastric cancers in mouse models. Orthotopic models showed bright and specific labeling with more than ten times higher tumor-to-background ratios compared to the control. This tumor-specific fluorescent antibody has promising potential as a clinical tool for improving visualization of gastric cancer margins during surgical resection.
JOURNAL OF SURGICAL RESEARCH
(2024)
Review
Surgery
Sarah Maki, Melissa Leon, Emily Glenn, Tiffany Tanner, Crystal Krause
Summary: This scoping review analyzed the literature on the use of broadband personality tests in the bariatric surgical population to optimize weight loss outcomes. The study found significant associations between personality scales and weight loss, but inconsistent reporting of outcome measures made it challenging to draw concrete conclusions. The American Society for Metabolic and Bariatric Surgery recommends standardization of outcome reporting to improve the reliability of predicting weight loss outcomes.
JOURNAL OF SURGICAL RESEARCH
(2024)