Journal
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
Volume 214, Issue -, Pages -Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.jphotobiol.2020.112084
Keywords
CuS nanoparticles; Carcinogen; Photocatalysis; Phototherapy; Anticancer
Categories
Funding
- TWAS (The World Academy of Sciences) [11-143 RG/PHA/AS_C-UNESCO FR: 3240262658]
- Higher Education Commission of Pakistan
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CuS nanoparticles can be used for the treatment of deep cancer and the photocatalytic remediation of carcinogenic pollutants, showing great potential for applications in the field of biomedicine and environmental remediation.
Herein, we report cost effective and body compatible CuS nanoparticles (NPs) derived from a single source precursor as photothermal agent for healing deep cancer and photocatalytic remediation of organic carcinogens. These NPs efficiently kill MCF7 cells (both in vivo and in vitro) under NIR irradiation by raising the temperature of tumor cells. Such materials can be used for the treatment of deep cancer as they can produce a heating effect using high wavelength and deeply penetrating NIR radiation. Furthermore, CuS NPs under solar light irradiation efficiently convert p-nitrophenol (PNP), an environmental carcinogen, to p-aminophenol (PAP) of pharmaceutical implication. In a nutshell, CuS can be used for the treatment of deep cancer and for the remediation of carcinogenic pollutants. There seems an intrinsic connection between the two functions of CuS NPs that need to be explored in length.
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