Exploring the Impact of Intestinal Fluid Components on the Solubility and Supersaturation of Danazol
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Exploring the Impact of Intestinal Fluid Components on the Solubility and Supersaturation of Danazol
Authors
Keywords
Developability, Gastrointestinal tract, Oral drug delivery, Poorly water-soluble drug(s), Preformulation, Solubility, Supersaturation
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-01-11
DOI
10.1016/j.xphs.2020.12.039
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Multidimensional analysis of human intestinal fluid composition
- (2020) Kate Pyper et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Comparison of induction methods for supersaturation: Amorphous dissolution versus solvent shift
- (2020) Jakob Plum et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments
- (2018) Cecilie Maria Madsen et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Crystallization from Supersaturated Solutions: Role of Lecithin and Composite Simulated Intestinal Fluid
- (2018) Anura S. Indulkar et al. PHARMACEUTICAL RESEARCH
- Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method
- (2017) Jakob Plum et al. MOLECULAR PHARMACEUTICS
- Physical chemistry of supersaturated solutions and implications for oral absorption
- (2016) Lynne S. Taylor et al. ADVANCED DRUG DELIVERY REVIEWS
- Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors
- (2016) Cecilie Maria Madsen et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Studying the Propensity of Compounds to Supersaturate: A Practical and Broadly Applicable Approach
- (2016) Henrik Palmelund et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Characterization of Human Duodenal Fluids in Fasted and Fed State Conditions
- (2016) Danny Riethorst et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Statistical investigation of simulated intestinal fluid composition on the equilibrium solubility of biopharmaceutics classification system class II drugs
- (2015) Ibrahim Khadra et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Study of a Standardized Taurocholate– Lecithin Powder for Preparing the Biorelevant Media FeSSIF and FaSSIF
- (2015) Bastian Kloefer et al. DISSOLUTION TECHNOLOGIES
- A Combination Turbidity and Supernatant Microplate Assay to Rank‐Order the Supersaturation Limits of Early Drug Candidates
- (2014) John S. Morrison et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Impact of Polymers on the Precipitation Behavior of Highly Supersaturated Aqueous Danazol Solutions
- (2014) Matthew J. Jackson et al. MOLECULAR PHARMACEUTICS
- Formulation and Performance of Danazol Nano-crystalline Suspensions and Spray Dried Powders
- (2014) Sumit Kumar et al. PHARMACEUTICAL RESEARCH
- Liquid–Liquid Phase Separation in Highly Supersaturated Aqueous Solutions of Poorly Water-Soluble Drugs: Implications for Solubility Enhancing Formulations
- (2013) Grace A. Ilevbare et al. CRYSTAL GROWTH & DESIGN
- Comparison of the Solubility and Dissolution of Drugs in FastedState Biorelevant Media (FaSSIF and FaSSIF-V2)
- (2013) Mathew Leigh et al. DISSOLUTION TECHNOLOGIES
- A review of drug solubility in human intestinal fluids: Implications for the prediction of oral absorption
- (2013) Patrick Augustijns et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Early pharmaceutical profiling to predict oral drug absorption: Current status and unmet needs
- (2013) Christel A.S. Bergström et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Formulation of a Danazol Cocrystal with Controlled Supersaturation Plays an Essential Role in Improving Bioavailability
- (2013) Scott L. Childs et al. MOLECULAR PHARMACEUTICS
- Evaluation of Drug Supersaturation by Thermodynamic and Kinetic Approaches for the Prediction of Oral Absorbability in Amorphous Pharmaceuticals
- (2012) Shunsuke Ozaki et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Intestinal drug solubility estimation based on simulated intestinal fluids: Comparison with solubility in human intestinal fluids
- (2011) Sarah Clarysse et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Solubility Advantage of Amorphous Pharmaceuticals, Part 3: Is Maximum Solubility Advantage Experimentally Attainable and Sustainable?
- (2011) Sharad B. Murdande et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Supersaturation–Nucleation Behavior of Poorly Soluble Drugs and its Impact on the Oral Absorption of Drugs in Thermodynamically High-Energy Forms
- (2011) Shunsuke Ozaki et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Precipitation in and Supersaturation of Contents of the Upper Small Intestine After Administration of Two Weak Bases to Fasted Adults
- (2011) Dimitrios Psachoulias et al. PHARMACEUTICAL RESEARCH
- Drug Supersaturation in Simulated Human Intestinal Fluids Representing Different Nutritional States
- (2010) Jan Bevernage et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies
- (2010) Karen Kleberg et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Simulating Fasted Human Intestinal Fluids: Understanding the Roles of Lecithin and Bile Acids
- (2010) Erik Söderlind et al. MOLECULAR PHARMACEUTICS
- Aqueous solubility of crystalline and amorphous drugs: Challenges in measurement
- (2010) Sharad B. Murdande et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Solubility Advantage of Amorphous Pharmaceuticals: II. Application of Quantitative Thermodynamic Relationships for Prediction of Solubility Enhancement in Structurally Diverse Insoluble Pharmaceuticals
- (2010) Sharad B. Murdande et al. PHARMACEUTICAL RESEARCH
- Ex vivo permeability experiments in excised rat intestinal tissue and in vitro solubility measurements in aspirated human intestinal fluids support age-dependent oral drug absorption
- (2009) Pieter Annaert et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Supersaturating Drug Delivery Systems: The Answer to Solubility-Limited Oral Bioavailability?
- (2009) Joachim Brouwers et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Solubility advantage of amorphous pharmaceuticals: I. A thermodynamic analysis
- (2009) Sharad B. Murdande et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Postprandial Changes in Solubilizing Capacity of Human Intestinal Fluids for BCS Class II Drugs
- (2009) Sarah Clarysse et al. PHARMACEUTICAL RESEARCH
- Postprandial Evolution in Composition and Characteristics of Human Duodenal Fluids in Different Nutritional States
- (2008) S. Clarysse et al. JOURNAL OF PHARMACEUTICAL SCIENCES
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now