Article
Medicine, General & Internal
Joo Hye Song, Ji Eun Kim, Hwe Hoon Chung, Sung Noh Hong, Heejung Kim, Eun Ran Kim, Dong Kyung Chang, Young-Ho Kim
Summary: Performing video capsule endoscopy within 24 hours of gastrointestinal bleeding can increase the diagnostic yield for patients with overt obscure gastrointestinal bleeding and may result in a higher rate of therapeutic intervention.
Article
Multidisciplinary Sciences
Yuga Komaki, Shuji Kanmura, Kazuki Yutsudo, Kosuke Kuwazuru, Fukiko Komaki, Akihito Tanaka, Hidehito Maeda, Shiho Arima, Shiroh Tanoue, Fumisato Sasaki, Shinichi Hashimoto, Masahisa Horiuchi, Akio Ido
Summary: This study retrospectively examined the clinical features and risk factors of obscure gastrointestinal bleeding (OGIB) in patients who underwent capsule endoscopy. The study found that the use of direct oral anticoagulants was frequently associated with OGIB, and OGIB patients without vascular lesions may be treated conservatively.
Article
Gastroenterology & Hepatology
Issei Hirata, Akiyoshi Tsuboi, Yuka Matsubara, Akihiko Sumioka, Takeshi Takasago, Hidenori Tanaka, Ken Yamashita, Hidehiko Takigawa, Takahiro Kotachi, Ryo Yuge, Yuji Urabe, Shiro Oka
Summary: This study investigated the long-term outcomes of 461 patients with OGIB after CE, revealing that rebleeding from the small bowel was rare in the P0 group, and a history of endoscopic hemostasis and P1 CE findings were predictive of small-bowel rebleeding.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Medicine, General & Internal
Shahrad Hakimian, Daniel Raines, George Reed, Mark Hanscom, Lilia Stefaniwsky, Matthew Petersile, Prashanth Rau, Anne Foley, David Cave
Summary: This study found that using Video Capsule Endoscopy (VCE) as an initial evaluation method for acute gastrointestinal bleeding during the COVID-19 pandemic appeared to be a safe and useful alternative to traditional upper endoscopy and colonoscopy. VCE was associated with increased detection of active bleeding and a reduced number of invasive procedures, avoiding personnel exposure to SARS-CoV-2 and saving personal protective equipment.
Article
Medicine, General & Internal
Iulia Ratiu, Raluca Lupusoru, Alina Popescu, Ioan Sporea, Adrian Goldis, Mirela Danila, Bogdan Miutescu, Tudor Moga, Andreea Barbulescu, Roxana Sirli
Summary: This observational retrospective study aimed to investigate the differences and associated factors between variceal and nonvariceal upper gastrointestinal bleeding (UGIB). The results showed that there was a higher rebleeding rate in patients with variceal bleeding.
Article
Medicine, General & Internal
Young Kyu Cho, Heesu Park, Jung Rock Moon, Seong Ran Jeon, Hyun Gun Kim, Tae Hee Lee, Junseok Park, Jin-Oh Kim, Joon Seong Lee, Hyeon Jeong Goong, Bong Min Ko, Suyeon Park
Summary: Despite negative CE and CT findings, patients with OGIB have a significant potential risk of rebleeding. While there was no significant difference in rebleeding rates between the P0 and P1 groups on CE, the P1 group has independent predictive factors.
Article
Materials Science, Multidisciplinary
Alex Abramson, Ameya R. Kirtane, Yunhua Shi, Grace Zhong, Joy E. Collins, Siddartha Tamang, Keiko Ishida, Alison Hayward, Jacob Wainer, Netra Unni Rajesh, Xiaoya Lu, Yuan Gao, Paramesh Karandikar, Chaoyang Tang, Aaron Lopes, Aniket Wahane, Daniel Reker, Morten Revsgaard Frederiksen, Brian Jensen, Robert Langer, Giovanni Traverso
Summary: Nucleic acids have opened up new possibilities for therapeutic drugs and vaccines. Oral delivery offers a preferred dosing method and enables local transfection of cells in the gastrointestinal tract. Researchers have developed mRNA nanoparticles and ingestible capsules to achieve transfection in the stomach, demonstrating efficacy in rodents and pigs.
Editorial Material
Medicine, General & Internal
Jeffrey L. Tokar, Jennifer T. Higa
Summary: This article reviews the presentation, treatment, and prevention of acute gastrointestinal bleeding (GIB) and emphasizes the collaborative care between internists and other specialists, as well as the pivotal role of primary care providers in managing acute GIB.
ANNALS OF INTERNAL MEDICINE
(2022)
Article
Gastroenterology & Hepatology
Phoebe A. Thwaites, Chu K. Yao, Jasjot Maggo, James John, Adam F. Chrimes, Rebecca E. Burgell, Jane G. Muir, Francis C. Parker, Daniel So, Kourosh Kalantar-Zadeh, Richard B. Gearry, Kyle J. Berean, Peter R. Gibson
Summary: The novel gas-sensing capsule and validated wireless motility capsule were compared for the assessment of gastroduodenal and ileocaecal junctions, with accurate identification of key anatomical landmarks. Intra-individual differences in transit times between capsules were likely due to physiological factors.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Hematology
Amir Samii, Mahshaad Norouzi, Abbas Ahmadi, Akbar Dorgalaleh
Summary: GIB is a serious condition that is difficult to manage due to heterogeneity in CBDs. Evaluating the hematological status and providing urgent interventions for high-risk patients are crucial. The best management strategy for CFD-related bleeding remains controversial.
SEMINARS IN THROMBOSIS AND HEMOSTASIS
(2022)
Article
Medicine, General & Internal
Samanta Romeo, Benedetto Neri, Michelangela Mossa, Maria Elena Riccioni, Ludovica Scucchi, Giorgia Sena, Saverio Potenza, Carmelina Petruzziello, Livia Biancone
Summary: In a real-world prospective study, small bowel capsule endoscopy (SBCE) demonstrated a high diagnostic yield in patients with obscure gastrointestinal bleeding (OGIB), detecting clinically relevant lesions in the majority of cases. SBCE was found to be valuable in determining the diagnostic work-up and clinical outcome in patients with OGIB.
INTERNAL AND EMERGENCY MEDICINE
(2022)
Article
Computer Science, Artificial Intelligence
Wei Wang, Xin Yang, Xin Li, Jinhui Tang
Summary: Automated diagnosis of digestive tract diseases from gastrointestinal endoscopy images is a high priority for improving diagnosis accuracy and efficiency. This paper presents a two-stage endoscopic image classification method that effectively combines midlevel CNN features and a capsule network, achieving superior results in gastrointestinal endoscopic image classification.
INTERNATIONAL JOURNAL OF INTELLIGENT SYSTEMS
(2022)
Article
Gastroenterology & Hepatology
Yuanyuan Yu, Zhuan Liao, Xi Jiang, Jun Pan, Wei Zhou, James Y. W. Lau
Summary: Magnet-controlled capsule endoscopy (MCCE) can be used as the first diagnostic tool for patients with acute upper gastrointestinal bleeding (AUGIB) as it has a high diagnostic yield and can guide subsequent treatment.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Chao-Chin Chao, Lein-Ray Mo, Susan C. Hu
Summary: This study evaluated the optimal timing for performing CE in patients with occult GI bleeding, with results indicating that the most optimal time is within three days after GI bleeding occurs.
BIOMED RESEARCH INTERNATIONAL
(2021)
Article
Gastroenterology & Hepatology
Loren Laine, Alan N. Barkun, John R. Saltzman, Myriam Martel, Grigorios I. Leontiadis
Summary: Systematic reviews were conducted to develop recommendations for the management of patients with overt upper gastrointestinal bleeding, suggesting risk assessment and red blood cell transfusion based on hemoglobin levels. Endoscopic therapy is recommended for ulcers with active bleeding or nonbleeding visible vessels, with repeat endoscopy and transcatheter embolization options available if therapy fails.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)