A Pan-Cancer Study of Somatic TERT Promoter Mutations and Amplification in 30,773 Tumors Profiled by Clinical Genomic Sequencing
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A Pan-Cancer Study of Somatic TERT Promoter Mutations and Amplification in 30,773 Tumors Profiled by Clinical Genomic Sequencing
Authors
Keywords
-
Journal
JOURNAL OF MOLECULAR DIAGNOSTICS
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2020-12-05
DOI
10.1016/j.jmoldx.2020.11.003
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Colorectal carcinomas containing hypermethylated MLH1 promoter and wild type BRAF/KRAS are enriched for targetable kinase fusions
- (2019) Emiliano Cocco et al. CANCER RESEARCH
- High yield of RNA sequencing for targetable kinase fusions in lung adenocarcinomas with no driver alteration detected by DNA sequencing and low tumor mutation burden
- (2019) Ryma Benayed et al. CLINICAL CANCER RESEARCH
- JAK2/PD-L1/PD-L2 (9p24.1) amplifications in renal cell carcinomas with sarcomatoid transformation: implications for clinical management
- (2019) Sounak Gupta et al. MODERN PATHOLOGY
- Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: old actors and new players
- (2019) Xiaotian Yuan et al. ONCOGENE
- Spectrum of TERT promoter mutations and mechanisms of activation in thyroid cancer
- (2019) Federica Panebianco et al. Cancer Medicine
- TERT promoter mutation in adult granulosa cell tumor of the ovary
- (2018) Jessica A. Pilsworth et al. MODERN PATHOLOGY
- Integrated Genomic Analysis of Hürthle Cell Cancer Reveals Oncogenic Drivers, Recurrent Mitochondrial Mutations, and Unique Chromosomal Landscapes
- (2018) Ian Ganly et al. CANCER CELL
- JAK2, PD-L1, and PD-L2 (9p24.1) Amplification in Metastatic Mucosal and Cutaneous Melanomas with Durable Response to Immunotherapy
- (2018) Sounak Gupta et al. HUMAN PATHOLOGY
- Next-Generation Sequencing–Based Assessment of JAK2, PD-L1, and PD-L2 Copy Number Alterations at 9p24.1 in Breast Cancer
- (2018) Sounak Gupta et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Diagnosis of known sarcoma fusions and novel fusion partners by targeted RNA sequencing with identification of a recurrent ACTB-FOSB fusion in pseudomyogenic hemangioendothelioma
- (2018) Guo Zhu et al. MODERN PATHOLOGY
- TERT structural rearrangements in metastatic pheochromocytomas
- (2017) Trisha Dwight et al. ENDOCRINE-RELATED CANCER
- Next-Generation Assessment of Human Epidermal Growth Factor Receptor 2 (ERBB2) Amplification Status
- (2017) Dara S. Ross et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients
- (2017) Ahmet Zehir et al. NATURE MEDICINE
- Telomeres in cancer: tumour suppression and genome instability
- (2017) John Maciejowski et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Scattered genomic amplification in dedifferentiated liposarcoma
- (2017) Nils Mandahl et al. Molecular Cytogenetics
- Genetic and Epigenetic Alterations of TERT Are Associated with Inferior Outcome in Adolescent and Young Adult Patients with Melanoma
- (2017) Brittani Seynnaeve et al. Scientific Reports
- Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma
- (2016) Siyuan Zheng et al. CANCER CELL
- TERTpromoter mutations in thyroid cancer
- (2016) Rengyun Liu et al. ENDOCRINE-RELATED CANCER
- Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers
- (2016) Iñigo Landa et al. JOURNAL OF CLINICAL INVESTIGATION
- TERT mutation in glioma: Frequency, prognosis and risk
- (2016) Yang Yuan et al. JOURNAL OF CLINICAL NEUROSCIENCE
- Telomerase Expression by Aberrant Methylation of the TERT Promoter in Melanoma Arising in Giant Congenital Nevi
- (2016) Yiping Fan et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Understanding TERT Promoter Mutations: A Common Path to Immortality
- (2016) R. J. A. Bell et al. MOLECULAR CANCER RESEARCH
- TERT Promoter Mutations Enhance Telomerase Activation by Long-Range Chromatin Interactions
- (2016) J. Min et al. Cancer Discovery
- Precision medicine at Memorial Sloan Kettering Cancer Center: clinical next-generation sequencing enabling next-generation targeted therapy trials
- (2015) David M. Hyman et al. DRUG DISCOVERY TODAY
- Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT)
- (2015) Donavan T. Cheng et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Telomerase activation by genomic rearrangements in high-risk neuroblastoma
- (2015) Martin Peifer et al. NATURE
- TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors
- (2015) Linda J Valentijn et al. NATURE GENETICS
- Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors
- (2015) Jeanette E. Eckel-Passow et al. NEW ENGLAND JOURNAL OF MEDICINE
- TERTpromoter mutations and telomerase reactivation in urothelial cancer
- (2015) Sumit Borah et al. SCIENCE
- The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer
- (2015) R. J. A. Bell et al. SCIENCE
- Integrated Genomic Characterization of Papillary Thyroid Carcinoma
- (2014) Nishant Agrawal et al. CELL
- TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities
- (2014) Christian Koelsche et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- TERT Promoter Mutation Status as an Independent Prognostic Factor in Cutaneous Melanoma
- (2014) Klaus G. Griewank et al. JNCI-Journal of the National Cancer Institute
- Comprehensive Analysis of ETS Family Members in Melanoma by Fluorescence In Situ Hybridization Reveals Recurrent ETV1 Amplification
- (2014) Rohit Mehra et al. Translational Oncology
- TERT Promoter Mutations Occur Early in Urothelial Neoplasia and Are Biomarkers of Early Disease and Disease Recurrence in Urine
- (2013) I. Kinde et al. CANCER RESEARCH
- Telomerase Reverse Transcriptase Promoter Mutations in Bladder Cancer: High Frequency Across Stages, Detection in Urine, and Lack of Association with Outcome
- (2013) Yves Allory et al. EUROPEAN UROLOGY
- Frequent SomaticTERTPromoter Mutations in Thyroid Cancer: Higher Prevalence in Advanced Forms of the Disease
- (2013) Iñigo Landa et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study
- (2013) Pedro Castelo-Branco et al. LANCET ONCOLOGY
- TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
- (2013) P. J. Killela et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Highly Recurrent TERT Promoter Mutations in Human Melanoma
- (2013) F. W. Huang et al. SCIENCE
- Frequency of TERT promoter mutations in human cancers
- (2013) João Vinagre et al. Nature Communications
- Cancer and Telomeres--An ALTernative to Telomerase
- (2012) J. W. Shay et al. SCIENCE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started