Article
Medicine, General & Internal
Sukhyun Ryu, Dasom Kim, Lae Young Jung, Baekjin Kim, Chang-Seop Lee
Summary: The COVID-19 pandemic did not result in a decrease in the number of patients with acute myocardial infarction. Patient response and intervention times remained unchanged, except for a significant reduction in door-to-balloon time among patients with ST-segment elevation myocardial infarction during the early phase of the pandemic.
Review
Cardiac & Cardiovascular Systems
Carlos Diaz-Arocutipa, Javier Torres-Valencia, Jose Saucedo-Chinchay, Cecilia Cuevas
Summary: COVID-19 can cause various cardiovascular diseases, including ST-segment elevation myocardial infarction (STEMI) and STEMI-mimickers. A systematic review was conducted to summarize the clinical features, management, and outcomes of COVID-19 patients with ST-segment elevation. A relatively high proportion of patients with ST-segment elevation had non-obstructive CAD, indicating a poor prognosis. These findings require confirmation in future studies.
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
(2021)
Article
Cardiac & Cardiovascular Systems
Audrey A. Y. Zhang, Nicholas W. S. Chew, Cheng Han Ng, Kailun Phua, Yin Nwe Aye, Aaron Mai, Gwyneth Kong, Kalyar Saw, Raymond C. C. Wong, William K. F. Kong, Kian-Keong Poh, Koo-Hui Chan, Adrian Fatt-Hoe Low, Chi-Hang Lee, Mark Yan-Yee Chan, Ping Chai, James Yip, Tiong-Cheng Yeo, Huay-Cheem Tan, Poay-Huan Loh
Summary: COVID-19 pandemic led to increased telemedicine use, with comparable long-term outcomes for STEMI patients. Teleconsultations were more frequent during the pandemic, with improved adherence to guideline-directed medical therapy and medication dosing, leading to favorable long-term prognosis.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Medicine, General & Internal
Tuncay Kiris, Eyup Avci, Tuba Ekin, Didar Elif Akgun, Mucahit Tiryaki, Arafat Yidirim, Kutluhan Hazir, Bektas Murat, Mehtap Yeni, Rojhad Altindag, Sefa Gul, Baran Arik, Tuncay Guzel, Selda Murat, Ahmet Oz, Mustafa Karabacak, Zihni Aktas, Tarik Yildirim, Baris Kilicaslan, Asim Oktay Ergene
Summary: The study aimed to compare the occurrence rates of MACCE in Turkish STEMI patients before and after COVID-19, showing no significant difference in MACCE rates between the two periods, but higher long-term MACCE and heart failure hospitalization rates in COVID-19 positive patients.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2022)
Article
Medicine, General & Internal
Sherif Ayad, Rafik Shenouda, Michael Henein
Summary: During the COVID-19 pandemic in 2020, the International Cardiac Center (ICC) hospital saw a reduction in PPCI procedures for STEMI patients, leading to longer treatment delays. The in-hospital mortality rate, rate of re-infarction, need for revascularization, and length of hospital stay also increased.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Ankeet S. Bhatt, Anubodh S. Varshney, Erica L. Goodrich, Jingyi Gong, Curtis Ginder, Balimkiz C. Senman, Matthew Johnson, Kayleigh Butler, Ann E. Woolley, James A. de Lemos, David A. Morrow, Erin A. Bohula
Summary: STEMI is a rare but detrimental complication in hospitalized COVID-19 patients, with low rates of coronary angiography and primary reperfusion therapy. Adaptations in treatment systems are needed to ensure timely and modern care for this population.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Medicine, General & Internal
Yong Hoon Kim, Ae-Young Her, Seung-Woon Rha, Cheol Ung Choi, Byoung Geol Choi, Ji Bak Kim, Soohyung Park, Dong Oh Kang, Ji Young Park, Sang-Ho Park, Myung Ho Jeong
Summary: Using a new-generation drug-eluting stent, the study compared the 2-year clinical outcomes of patients with diabetes mellitus (DM) and non-DM concomitant with a non-ST-segment elevation myocardial infarction (NSTEMI) and an ST-segment elevation myocardial infarction (STEMI) who underwent percutaneous coronary intervention. The results showed higher non-CD rates in patients with DM and higher CD rates in patients without DM in the NSTEMI group.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Julianne M. Evers, Nancy L. York, Heather Owens, Melanie G. Hardin-Pierce
Summary: This study aimed to evaluate the effectiveness of implementing a STEMI network in reducing DTB times at a large metropolitan academic hospital in the southeastern United States. The results showed that the implementation of the STEMI network effectively decreased overall DTB times for patients diagnosed with STEMI.
JOURNAL OF CARDIOVASCULAR NURSING
(2022)
Article
Medicine, General & Internal
Youngchul Choi, Kiwook Kim, Joo Suk Oh, Hyun Ho Jeong, Jung Taek Park, Yeon Young Kyong, Young Min Oh, Se Min Choi, Kyoung Ho Choi
Summary: This study found that DTB time was significantly delayed in patients presenting with STEMI-equivalent ECGs. Prompt recognition of STEMI-equivalent ECGs may reduce DTB time and improve clinical outcomes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Yong Hoon Kim, Ae-Young Her, Myung Ho Jeong, Byeong-Keuk Kim, Sung-Jin Hong, Seung-Jun Lee, Chul-Min Ahn, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang
Summary: The study compared the 2-year major clinical outcomes between STEMI and NSTEMI patients who are current smokers treated with PCI, and found no significant difference in outcomes. Further research is needed to confirm these results.
Article
Medicine, General & Internal
Tomasz Tokarek, Artur Dziewierz, Krzysztof Piotr Malinowski, Tomasz Rakowski, Stanislaw Bartus, Dariusz Dudek, Zbigniew Siudak
Summary: The study investigated treatment delay and clinical outcomes in COVID-19 positive and negative patients with ST-segment elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention (PCI) during on- and off-hours, finding that COVID-19 diagnosis resulted in longer time from first medical contact to angiography, without affecting mortality and prevalence of other periprocedural complications.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Juan Carlos C. Montoy, Yu-Chu Shen, Ralph G. Brindis, Harlan M. Krumholz, Renee Y. Hsia
Summary: The study found that regionalization programs for ST-segment-elevation myocardial infarction did not have a statistically significant impact on the treatment and outcomes of patients with NSTEMIs. Over the study period, there were slight increases in early angiography rates and decreases in mortality rates, but these changes were not directly related to regionalization policies.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Jihoon Kim, Young Bin Song, Ju-Hyeon Oh, Deok-Kyu Cho, Jin Bae Lee, Sang-Hyun Kim, Jin-Ok Jeong, Jang-Ho Bae, Byung Ok Kim, Jang Hyun Cho, Il-Woo Suh, Doo-il Kim, Hoon-Ki Park, Jong-Seon Park, Woong Gil Choi, Wang Soo Lee, Ki Hong Choi, Taek Kyu Park, Joo Myung Lee, Jeong Hoon Yang, Jin-Ho Choi, Seung-Hyuk Choi, Hyeon-Cheol Gwon, Joon-Hyung Doh, Joo-Yong Hahn
Summary: Prolonged dual antiplatelet therapy (DAPT) for 12 months or more can reduce the risk of recurrent myocardial infarction or stent thrombosis regardless of the type of myocardial infarction. However, it also increases the risk of bleeding.
CIRCULATION JOURNAL
(2021)
Article
Medicine, General & Internal
Steffen Desch, Anne Freund, Ibrahim Akin, Michael Behnes, Michael R. Preusch, Thomas A. Zelniker, Carsten Skurk, Ulf Landmesser, Tobias Graf, Ingo Eitel, Georg Fuernau, Hendrik Haake, Peter Nordbeck, Fabian Hammer, Stephan B. Felix, Christian Hassager, Thomas Engstrom, Stephan Fichtlscherer, Jakob Ledwoch, Karsten Lenk, Michael Joner, Stephan Steiner, Christoph Liebetrau, Ingo Voigt, Uwe Zeymer, Michael Brand, Roland Schmitz, Jan Horstkotte, Claudius Jacobshagen, Janine Poss, Mohamed Abdel-Wahab, Philipp Lurz, Alexander Jobs, Suzanne de Waha-Thiele, Denise Olbrich, Frank Sandig, Inke R. Koenig, Sabine Brett, Maren Vens, Kathrin Klinge, Holger Thiele
Summary: Among patients with resuscitated out-of-hospital cardiac arrest without ST-segment elevation, the immediate angiography strategy did not provide any benefit over a delayed or selective strategy in terms of the 30-day risk of death from any cause.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Carl Vahldieck, Benedikt Fels, Samuel Loening, Laura Nickel, Joachim Weil, Kristina Kusche-Vihrog
Summary: This study found that damage to the endothelial glycocalyx (eGC) during ST-elevation myocardial infarction (STEMI) is associated with the duration of door-to-balloon time (D2B) and endothelial function. A D2B > 60 min resulted in loss of eGC, endothelial dysfunction, increased inflammation, and prolonged hospital stay. The findings suggest that D2B is a crucial factor for eGC damage during STEMI, and evaluating the condition of eGC may serve as an important predictor for endothelial function in STEMI patients.