Bioavailability and antioxidant activity of nanotechnology-based botanic antioxidants

Botanic bioactive substances have issues with their solubility, stability, and oral bioavailability in the application, which could be improved by nanotechnologies. In another hands, green synthesis of nanoparticles (NPs) with plant extract is also a promising technology for preparation of NPs due to its safety advantage, yet the bioactive botanic substances that could be more than the assistant of the green synthesis of NPs. Based on the above concerns, this review summarized the preparation of botanic NPs with various plant extract, their solubility, stability, and oral bioavailability; specific attention has been paid to the botanic Ag/Au NPs, their capacity of antioxidant, bioavailability, antimicrobial, anti-inflammatory, and anticancer.

Automated summary

Botanic bioactive substances face challenges of solubility, stability, and oral bioavailability in application, which could be addressed with nanotechnologies. Green synthesis of nanoparticles using plant extract is a promising technology, with bioactive botanic substances playing a crucial role. The review highlights the preparation of botanic NPs with different plant extracts, emphasizing their solubility, stability, bioavailability, and functions including antioxidant, antimicrobial, anti-inflammatory, and anticancer properties.