Design and evaluation of combined atorvastatin and ezetimibe optimized self- nano emulsifying drug delivery system

Nanostructured lipid carriers for improved oral delivery and prolonged antihyperlipidemic effect of simvastatin

(2018) Heba A. Fathi et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Preparing composite nanoparticles for immediate drug release by modifying electrohydrodynamic interfaces during electrospraying

(2018) Zhe-Peng Liu et al.   POWDER TECHNOLOGY

Evaluation of a self-nanoemulsifying docetaxel delivery system

(2018) S. Akhtartavan et al.   BIOMEDICINE & PHARMACOTHERAPY

Systematic development of design of experiments (DoE) optimised self-microemulsifying drug delivery system of Zotepine

(2017) Hitesh Dalvadi et al.   JOURNAL OF MICROENCAPSULATION

Development and optimisation of atorvastatin calcium loaded self-nanoemulsifying drug delivery system (SNEDDS) for enhancing oral bioavailability: in vitro and in vivo evaluation

(2017) Abdulsalam M. Kassem et al.   JOURNAL OF MICROENCAPSULATION

Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions

(2016) Michael G. Silverman et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Self-nanoemulsifying drug delivery system (SNEDDS) with enhanced solubilization of nystatin for treatment of oral candidiasis: Design, optimization, in vitro and in vivo evaluation

(2016) Ahmed Alaa Kassem et al.   JOURNAL OF MOLECULAR LIQUIDS

Self-emulsifying drug delivery systems as a tool to improve solubility and bioavailability of resveratrol

(2016) Gehan Balata et al.   Drug Design Development and Therapy

Formulation and in Vitro Evaluation of Self-microemulsifying Drug Delivery System Containing Fixed-Dose Combination of Atorvastatin and Ezetimibe

(2015) Kyu-Mok Hwang et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Effective surfactants blend concentration determination for o/w emulsion stabilization by two nonionic surfactants by simple linear regression

(2015) AK Hassan   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

Novel self-nanoemulsifying self-nanosuspension (SNESNS) for enhancing oral bioavailability of diacerein: Simultaneous portal blood absorption and lymphatic delivery

(2015) Hanan M. El-Laithy et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Effect of Naturally Random Allocation to Lower Low-Density Lipoprotein Cholesterol on the Risk of Coronary Heart Disease Mediated by Polymorphisms in NPC1L1, HMGCR, or Both

(2015) Brian A. Ference et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Self-nanoemulsifying drug delivery system (SNEDDS) of the poorly water-soluble grapefruit flavonoid Naringenin: design, characterization,in vitroandin vivoevaluation

(2014) Abdul Wadood Khan et al.   DRUG DELIVERY

Formulation of solid self-nanoemulsifying drug delivery systems usingN-methyl pyrrolidone as cosolvent

(2014) Anuj G. Agrawal et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

A quality by design approach to optimization of emulsions for electrospinning using factorial and D-optimal designs

(2014) Mariam A. Badawi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

A TPGS-incorporating nanoemulsion of paclitaxel circumvents drug resistance in breast cancer

(2014) Huihui Bu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Inactivating Mutations in NPC1L1 and Protection from Coronary Heart Disease

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Nanoemulsion: an advanced mode of drug delivery system

(2014) Manjit Jaiswal et al.   3 Biotech

Self nanoemulsifying drug delivery system (SNEDDS) of Rosuvastatin calcium: Design, formulation, bioavailability and pharmacokinetic evaluation

(2013) Krishnamoorthy Balakumar et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Ultra-fine self nanoemulsifying drug delivery system for transdermal delivery of meloxicam: Dependency on the type of surfactants

(2013) Mohamed M. Badran et al.   JOURNAL OF MOLECULAR LIQUIDS

The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials

(2013)   LANCET

Development, Optimization, and Characterization of Solid Self-Nanoemulsifying Drug Delivery Systems of Valsartan Using Porous Carriers

(2012) Sarwar Beg et al.   AAPS PHARMSCITECH

Optimization of self nanoemulsifying drug delivery system for poorly water-soluble drug using response surface methodology

(2012) Shan Ren et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Novel lipid based oral formulation of curcumin: Development and optimization by design of experiments approach

(2012) Yogesh B. Pawar et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Preparation of Candesartan and Atorvastatin Nanoparticles by Solvent Evaporation

(2012) Eliska Vaculikova et al.   MOLECULES

Oral self emulsifying powder of lercanidipine hydrochloride: Formulation and evaluation

(2012) Venkata Raman Kallakunta et al.   POWDER TECHNOLOGY

Self-nanoemulsifying drug delivery system for adefovir dipivoxil: Design, characterization, in vitro and ex vivo evaluation

(2011) Shweta Gupta et al.   COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS

Formulation and Physicochemical Characterization of Imwitor 308 Based Self Microemulsifying Drug Delivery Systems

(2010) Sara Zargar-Shoshtari et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

SNEDDS containing bioenhancers for improvement of dissolution and oral absorption of lacidipine. I: Development and optimization

(2010) Emad B. Basalious et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study

(2010) Martin J O'Donnell et al.   LANCET

Transmission Electron Microscopy of Lipid Vesicles for Drug Delivery: Comparison between Positive and Negative Staining

(2010) Valentina Bello et al.   MICROSCOPY AND MICROANALYSIS

Enhancement of oral bioavailability of atorvastatin calcium by self-emulsifying drug delivery systems (SEDDS)

(2010) Pawan J. Kadu et al.   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

Oral bioavailability of silymarin phytocomplex formulated as self-emulsifying pellets

(2010) T. Iosio et al.   PHYTOMEDICINE

Critical Factors Influencing the In Vivo Performance of Long-acting Lipophilic Solutions—Impact on In Vitro Release Method Design

(2009) Susan Weng Larsen et al.   AAPS Journal

Co-solvent Evaporation Method for Enhancement of Solubility and Dissolution Rate of Poorly Aqueous Soluble Drug Simvastatin: In vitro–In vivo Evaluation

(2009) Priyanka Pandya et al.   AAPS PHARMSCITECH

Nanoemulsion Components Screening and Selection: a Technical Note

(2009) Adnan Azeem et al.   AAPS PHARMSCITECH

Self-nanoemulsifying drug delivery systems of tamoxifen citrate: Design and optimization

(2009) Yosra S.R. Elnaggar et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Solid self-emulsifying nitrendipine pellets: Preparation and in vitro/in vivo evaluation

(2009) Zhiyuan Wang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Efficacy and Safety of Ezetimibe Added on to Atorvastatin (20 mg) Versus Uptitration of Atorvastatin (to 40 mg) in Hypercholesterolemic Patients at Moderately High Risk for Coronary Heart Disease††Conflicts of interest: Dr. Conard served as a consultant and advisor for Merck & Company and Merck/Schering-Plough. Dr. Bays received research grants from Amylin, San Diego, California, Amgen, Thousand Oaks, California, J&J, Langhorne, Pennsylvania, Aegerion, Bridgewater, New Jersey, Abbott, Chicago, Illinois, Arena Pharmaceuticals, San Diego, California, GlaxoSmithKline (Glaxo), London, UK, Hoffmann LaRoche, Nutley, New Jersey, Merck, Whitehouse Station, New Jersey, MSP, Kenilworth, New Jersey, Metabolex, San Jose, California, Schering-Plough, Kenilworth, New Jersey, Orexigen, San Diego, California, Reliant, Liberty Corner, New Jersey, Sciele, Atlanta, Georgia, Takeda, Osaka, Japan, TAP, Lake Forest, Illinois, and Vivus, Mountain View, California; received speakers' honoraria from Abbott, Daiichi Sankyo, Tokyo, Japan, GlaxoSmithKline, Reliant, Merck & Company, Merck/Schering-Plough, and Schering-Plough; received honoraria from Abbott, AstraZeneca, London, UK (Wilmington, Delaware, US Headquarters), Daiichi Sankyo, GlaxoSmithKline, Reliant, Merck & Company, Merck/Schering-Plough, and Schering-Plough; and served as a consultant and advisor for Abbott, GlaxoSmithKline, Metabolex, San Jose, California, Reliant, Takeda, AstraZeneca, and Essentialis, Carlsbad, California. Dr. Leiter received grants and speakers' honoraria from and served as a consultant and advisor for AstraZeneca, Merck & Company, Merck/Schering-Plough, and Pfizer, New York, New York. Mr. Bird, Mr. Rubino, and Drs. Lowe, Tomassini, and Tershakovec are employees of Merck & Company and may own stock and/or hold stock options in the company.

(2008) Scott E. Conard et al.   AMERICAN JOURNAL OF CARDIOLOGY

Development of solid self-emulsifying drug delivery systems: preparation techniques and dosage forms

(2008) Bo Tang et al.   DRUG DISCOVERY TODAY

Physicochemical properties and oral bioavailability of amorphous atorvastatin hemi-calcium using spray-drying and SAS process

(2008) Jeong-Soo Kim et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Dissolution and powder flow characterization of solid self-emulsified drug delivery system (SEDDS)

(2008) Vikas Agarwal et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Bi-layered self-emulsifying pellets prepared by co-extrusion and spheronization: Influence of formulation variables and preliminary study on the in vivo absorption

(2007) Tamara Iosio et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS