TP53 gene mutation analysis in chronic lymphocytic leukemia by nanopore MinION sequencing

Nanopore sequencing detects structural variants in cancer

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NanoOK: multi-reference alignment analysis of nanopore sequencing data, quality and error profiles

(2015) Richard M. Leggett et al.   BIOINFORMATICS

Long-Read Single Molecule Real-Time Full Gene Sequencing of Cytochrome P450-2D6

(2015) Wanqiong Qiao et al.   HUMAN MUTATION

MinION takes center stage

(2015) Nicole Rusk   NATURE METHODS

A complete bacterial genome assembled de novo using only nanopore sequencing data

(2015) Nicholas J Loman et al.   NATURE METHODS

Improved data analysis for the MinION nanopore sequencer

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poRe: an R package for the visualization and analysis of nanopore sequencing data

(2014) Mick Watson et al.   BIOINFORMATICS

Poretools: a toolkit for analyzing nanopore sequence data

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TP53 Mutation Analysis in Clinical Practice: Lessons From Chronic Lymphocytic Leukemia

(2014) Jitka Malcikova et al.   HUMAN MUTATION

A reference bacterial genome dataset generated on the MinION™ portable single-molecule nanopore sequencer

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Fludarabine plus alemtuzumab (FA) front-line treatment in young patients with chronic lymphocytic leukemia (CLL) and an adverse biologic profile

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Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

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VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

(2012) D. C. Koboldt et al.   GENOME RESEARCH

ERIC recommendations on TP53 mutation analysis in chronic lymphocytic leukemia

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Mutational Status of theTP53Gene As a Predictor of Response and Survival in Patients With Chronic Lymphocytic Leukemia: Results From the LRF CLL4 Trial

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Decreased TET2 gene expression during chronic myeloid leukemia progression

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Integrative genomics viewer

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Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

GeneScreen: a program for high-throughput mutation detection in DNA sequence electropherograms

(2010) I. M. Carr et al.   JOURNAL OF MEDICAL GENETICS

Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences

(2010) Jeremy Goecks et al.   GENOME BIOLOGY

Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial

(2009) T. Zenz et al.   BLOOD

De novo deletion 17p13.1 chronic lymphocytic leukemia shows significant clinical heterogeneity: the M. D. Anderson and Mayo Clinic experience

(2009) C. S. Tam et al.   BLOOD

The Prognostic Value of TP53 Mutations in Chronic Lymphocytic Leukemia Is Independent of Del17p13: Implications for Overall Survival and Chemorefractoriness

(2009) D. Rossi et al.   CLINICAL CANCER RESEARCH

Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up

(2008) T. Zenz et al.   BLOOD