Lactose-appended β-cyclodextrin as an effective nanocarrier for brain delivery

Large-Scale Quantitative Comparison of Plasma Transmembrane Proteins between Two Human Blood–Brain Barrier Model Cell Lines, hCMEC/D3 and HBMEC/ciβ

(2019) Takeshi Masuda et al.   MOLECULAR PHARMACEUTICS

CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing

(2019) Kornel Labun et al.   NUCLEIC ACIDS RESEARCH

In vivo Efficacy and Safety Evaluation of Lactosyl-β-cyclodextrin as a Therapeutic Agent for Hepatomegaly in Niemann-Pick Type C Disease

(2019) Yuki Maeda et al.   Nanomaterials

Nanodisk-based glioma-targeted drug delivery enabled by a stable glycopeptide

(2018) Huan Wang et al.   JOURNAL OF CONTROLLED RELEASE

Current Strategies for Brain Drug Delivery

(2018) Xiaowei Dong   Theranostics

Induction of mitophagy-mediated antitumor activity with folate-appended methyl-β-cyclodextrin

(2017) Kazuhisa Kameyama et al.   International Journal of Nanomedicine

Intrathecal 2-hydroxypropyl-β-cyclodextrin decreases neurological disease progression in Niemann-Pick disease, type C1: a non-randomised, open-label, phase 1–2 trial

(2017) Daniel S Ory et al.   LANCET

Identification of neuronal and angiogenic growth factors in an in vitro blood-brain barrier model system: Relevance in barrier integrity and tight junction formation and complexity

(2017) Christian Freese et al.   MICROVASCULAR RESEARCH

Inducer exclusion in Firmicutes: insights into the regulation of a carbohydrate ATP binding cassette transporter from Lactobacillus casei BL23 by the signal transducing protein P-Ser46-HPr

(2017) Constanze Homburg et al.   MOLECULAR MICROBIOLOGY

Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain

(2017) Y. Anraku et al.   Nature Communications

Ternary inclusion complex formation and stabilization of limaprost, a prostaglandin E 1 derivative, in the presence of α- and β-cyclodextrins in the solid state

(2016) Yasuo Inoue et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Glucose Transporters at the Blood-Brain Barrier: Function, Regulation and Gateways for Drug Delivery

(2016) Simon G. Patching   MOLECULAR NEUROBIOLOGY

From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery

(2016) William A. Banks   NATURE REVIEWS DRUG DISCOVERY

Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming

(2016) Sebastian Zimmer et al.   Science Translational Medicine

Cholesterol lowering effects of mono-lactose-appended β-cyclodextrin in Niemann–Pick type C disease-like HepG2 cells

(2015) Keiichi Motoyama et al.   Beilstein Journal of Organic Chemistry

Galectin-1 suppresses methamphetamine induced neuroinflammation in human brain microvascular endothelial cells: Neuroprotective role in maintaining blood brain barrier integrity

(2015) Neil U. Parikh et al.   BRAIN RESEARCH

High glucose-induced Galectin-1 in human podocytes implicates the involvement of Galectin-1 in diabetic nephropathy

(2014) Yinghong Liu et al.   CELL BIOLOGY INTERNATIONAL

Cell-Based in Vitro Blood–Brain Barrier Model Can Rapidly Evaluate Nanoparticles’ Brain Permeability in Association with Particle Size and Surface Modification

(2014) Sanshiro Hanada et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In Vitro and in Vivo Evaluation of Lactoferrin-Conjugated Liposomes as a Novel Carrier to Improve the Brain Delivery

(2013) Feng-Yun Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Quantitative analysis of the brain-targeted delivery of drugs and model compounds using nano-delivery systems

(2013) Luba Kozlovskaya et al.   JOURNAL OF CONTROLLED RELEASE

Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor

(2013) D. T. Wiley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of the Presence or Absence of a Protein Corona on Silica Nanoparticle Uptake and Impact on Cells

(2012) Anna Lesniak et al.   ACS Nano

Investigation of glucose-modified liposomes using polyethylene glycols with different chain lengths as the linkers for brain targeting

(2012) Fulan Xie et al.   International Journal of Nanomedicine

Quantitative Targeted Absolute Proteomic Analysis of Transporters, Receptors and Junction Proteins for Validation of Human Cerebral Microvascular Endothelial Cell Line hCMEC/D3 as a Human Blood–Brain Barrier Model

(2012) Sumio Ohtsuki et al.   MOLECULAR PHARMACEUTICS

Modern methods for delivery of drugs across the blood–brain barrier

(2011) Yan Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors

(2011) Yasuo Uchida et al.   JOURNAL OF NEUROCHEMISTRY

Grand challenges in global mental health

(2011) Pamela Y. Collins et al.   NATURE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

In vitroandin vivoinvestigation of glucose-mediated brain-targeting liposomes

(2010) Yao Qin et al.   JOURNAL OF DRUG TARGETING

Drug Targeting of Erythropoietin Across the Primate Blood-Brain Barrier with an IgG Molecular Trojan Horse

(2010) R. J. Boado et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Surface Characteristics of Nanoparticles Determine Their Intracellular Fate in and Processing by Human Blood–Brain Barrier Endothelial Cells In Vitro

(2010) Julia V Georgieva et al.   MOLECULAR THERAPY

Niemann-Pick disease type C

(2010) Marie T Vanier   Orphanet Journal of Rare Diseases

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Lactoferrin-conjugated PEG–PLA nanoparticles with improved brain delivery: In vitro and in vivo evaluations

(2008) Kaili Hu et al.   JOURNAL OF CONTROLLED RELEASE