A high-throughput method for fast detecting unfolding of monoclonal antibodies on cation exchange resins

Cation exchange frontal chromatography for the removal of monoclonal antibody aggregates

(2019) Matthew T. Stone et al.   JOURNAL OF CHROMATOGRAPHY A

Conformational changes of antibodies upon adsorption onto hydrophobic interaction chromatography surfaces

(2018) Beate Beyer et al.   JOURNAL OF CHROMATOGRAPHY A

Effect of mass overloading on binding and elution of unstable proteins in hydrophobic interaction chromatography

(2017) Renata Muca et al.   JOURNAL OF CHROMATOGRAPHY A

Surface induced three-peak elution behavior of a monoclonal antibody during cation exchange chromatography

(2016) Jing Guo et al.   JOURNAL OF CHROMATOGRAPHY A

Unfolding and aggregation of monoclonal antibodies on cation exchange columns: Effects of resin type, load buffer, and protein stability

(2015) Jing Guo et al.   JOURNAL OF CHROMATOGRAPHY A

Double-peak elution profile of a monoclonal antibody in cation exchange chromatography is caused by histidine-protonation-based charge variants

(2015) Haibin Luo et al.   JOURNAL OF CHROMATOGRAPHY A

Effects of salt-induced reversible self-association on the elution behavior of a monoclonal antibody in cation exchange chromatography

(2014) Haibin Luo et al.   JOURNAL OF CHROMATOGRAPHY A

Unfolding of a model protein on ion exchange and mixed mode chromatography surfaces

(2014) Adrian M. Gospodarek et al.   JOURNAL OF CHROMATOGRAPHY A

Unfolding and aggregation of a glycosylated monoclonal antibody on a cation exchange column. Part II. Protein structure effects by hydrogen deuterium exchange mass spectrometry

(2014) Jing Guo et al.   JOURNAL OF CHROMATOGRAPHY A

Unfolding and aggregation of a glycosylated monoclonal antibody on a cation exchange column. Part I. Chromatographic elution and batch adsorption behavior

(2014) Jing Guo et al.   JOURNAL OF CHROMATOGRAPHY A

High-Throughput Thermal Scanning for Protein Stability: Making a Good Technique More Robust

(2013) Shane A. Seabrook et al.   ACS Combinatorial Science

Cation exchange surface-mediated denaturation of an aglycosylated immunoglobulin (IgG1)

(2012) Ron Gillespie et al.   JOURNAL OF CHROMATOGRAPHY A

Thermal Denaturation Assays in Chemical Biology

(2011) Guillermo Senisterra et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

A high-throughput fluorescence chemical denaturation assay as a general screen for protein–ligand binding

(2010) Kumaran Mahendrarajah et al.   ANALYTICAL BIOCHEMISTRY

Behavior of human serum albumin on strong cation exchange resins: II. Model analysis

(2010) Agnes Voitl et al.   JOURNAL OF CHROMATOGRAPHY A

Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation

(2010) Zhongqi Zhang et al.   PROTEIN SCIENCE

Hydrophobic interaction chromatography of proteins: Thermodynamic analysis of conformational changes

(2009) Rene Ueberbacher et al.   JOURNAL OF CHROMATOGRAPHY A

Hydrophobic interaction chromatography of proteins

(2008) Rene Ueberbacher et al.   JOURNAL OF CHROMATOGRAPHY A