The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets

Determination of Optimal Sample Size for Quantification of β-Cell Area, Amyloid Area and β-Cell Apoptosis in Isolated Islets

(2015) Daniel T. Meier et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

β-Cell Loss and β-Cell Apoptosis in Human Type 2 Diabetes Are Related to Islet Amyloid Deposition

(2011) Catherine A. Jurgens et al.   AMERICAN JOURNAL OF PATHOLOGY

Exendin-4 increases islet amyloid deposition but offsets the resultant beta cell toxicity in human islet amyloid polypeptide transgenic mouse islets

(2011) K. Aston-Mourney et al.   DIABETOLOGIA

Sensitivity of Amyloid Formation by Human Islet Amyloid Polypeptide to Mutations at Residue 20

(2011) Ping Cao et al.   JOURNAL OF MOLECULAR BIOLOGY

Expression of wild-type and mutant S20G hIAPP in physiologic knock-in mouse models fails to induce islet amyloid formation, but induces mild glucose intolerance

(2011) Henry J Hiddinga et al.   Journal of Diabetes Investigation

Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis

(2009) S. Zraika et al.   DIABETOLOGIA

Conformation Preorganization: Effects of S20G Mutation on the Structure of Human Islet Amyloid Polypeptide Segment

(2009) Weixin Xu et al.   JOURNAL OF PHYSICAL CHEMISTRY B