Changes in beta cell function occur in prediabetes and early disease in the Lepr db mouse model of diabetes

Enhanced glucose-induced intracellular signaling promotes insulin hypersecretion: Pancreatic beta-cell functional adaptations in a model of genetic obesity and prediabetes

(2015) Esperanza Irles et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The secretory deficit in islets from db/db mice is mainly due to a loss of responding beta cells

(2014) Oanh H. Do et al.   DIABETOLOGIA

Glucose principally regulates insulin secretion in mouse islets by controlling the numbers of granule fusion events per cell

(2013) Jiun T. Low et al.   DIABETOLOGIA

Insulin Hypersecretion in Islets From Diet-Induced Hyperinsulinemic Obese Female Mice Is Associated With Several Functional Adaptations in Individual β-Cells

(2013) Alejandro Gonzalez et al.   ENDOCRINOLOGY

Deciphering Dead-End Docking of Large Dense Core Vesicles in Bovine Chromaffin Cells

(2013) Sandra Hugo et al.   JOURNAL OF NEUROSCIENCE

Characterisation of Age-Dependent Beta Cell Dynamics in the Male db/db Mice

(2013) Louise S. Dalbøge et al.   PLoS One

Diabetes Mellitus and the β Cell: The Last Ten Years

(2012) Frances M. Ashcroft et al.   CELL

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

Reduced Insulin Exocytosis in Human Pancreatic  -Cells With Gene Variants Linked to Type 2 Diabetes

(2012) A. H. Rosengren et al.   DIABETES

Multivesicular exocytosis in rat pancreatic beta cells

(2011) M. B. Hoppa et al.   DIABETOLOGIA

Class IA Phosphatidylinositol 3-Kinase in Pancreatic β Cells Controls Insulin Secretion by Multiple Mechanisms

(2010) Kazuma Kaneko et al.   Cell Metabolism

The beta cell lesion in type 2 diabetes: there has to be a primary functional abnormality

(2009) S. E. Kahn et al.   DIABETOLOGIA