Extreme obesity induces massive beta cell expansion in mice through self-renewal and does not alter the beta cell lineage

Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces β Cell Proliferation

(2016) Marta Szabat et al.   Cell Metabolism

Salivary Gland Homeostasis Is Maintained through Acinar Cell Self-Duplication

(2015) Marit H. Aure et al.   DEVELOPMENTAL CELL

Insulin demand regulates β cell number via the unfolded protein response

(2015) Rohit B. Sharma et al.   JOURNAL OF CLINICAL INVESTIGATION

Betatrophin Versus Bitter-Trophin and the Elephant in the Room: Time for a New Normal in  -Cell Regeneration Research

(2014) A. F. Stewart   DIABETES

Adaptive β-cell proliferation increases early in high-fat feeding in mice, concurrent with metabolic changes, with induction of islet cyclin D2 expression

(2013) Rachel E. Stamateris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Elevated Mouse Hepatic Betatrophin Expression Does Not Increase Human  -Cell Replication in the Transplant Setting

(2013) Y. Jiao et al.   DIABETES

 -Cells Are Not Generated in Pancreatic Duct Ligation-Induced Injury in Adult Mice

(2013) M. M. Rankin et al.   DIABETES

 -Cell Mass and Turnover in Humans: Effects of obesity and aging

(2012) Y. Saisho et al.   DIABETES CARE

Clonally dominant cardiomyocytes direct heart morphogenesis

(2012) Vikas Gupta et al.   NATURE

Structure and dynamics of a primordial catalytic fold generated by in vitro evolution

(2012) Fa-An Chao et al.   Nature Chemical Biology

Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas

(2011) J. L. Kopp et al.   DEVELOPMENT

Reduced Proliferation and a High Apoptotic Frequency of Pancreatic Beta Cells Contribute to Genetically-determined Diabetes Susceptibility of db/db BKS Mice

(2011) R. Puff et al.   HORMONE AND METABOLIC RESEARCH

Increased β-cell volume in mice fed a high-fat diet: A dynamic study over 12 months

(2011) Jonatan Ahrén et al.   Islets

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

Glucose and aging control the quiescence period that follows pancreatic beta cell replication

(2010) S. J. Salpeter et al.   DEVELOPMENT

 -Cell Failure in Diet-Induced Obese Mice Stratified According to Body Weight Gain: Secretory Dysfunction and Altered Islet Lipid Metabolism Without Steatosis or Reduced  -Cell Mass

(2010) M.-L. Peyot et al.   DIABETES

Significant Human β-Cell Turnover Is Limited to the First Three Decades of Life as Determined byin VivoThymidine Analog Incorporation and Radiocarbon Dating

(2010) S. Perl et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Pancreatic neurogenin 3-expressing cells are unipotent islet precursors

(2009) R. Desgraz et al.   DEVELOPMENT

Age-Dependent Decline in  -Cell Proliferation Restricts the Capacity of  -Cell Regeneration in Mice

(2009) S.-I. Tschen et al.   DIABETES

Adaptive  -Cell Proliferation Is Severely Restricted With Advanced Age

(2009) M. M. Rankin et al.   DIABETES

The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation

(2009) M. Cnop et al.   DIABETOLOGIA

Cyclin D2 Protein Stability Is Regulated in Pancreatic β-Cells

(2009) Lu Mei He et al.   MOLECULAR ENDOCRINOLOGY

Adaptation to intermittent stress promotes maintenance of β-cell compensation: comparison with food restriction

(2008) Holly E. Bates et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

 -Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of  -Cell Mass in Humans

(2008) J. J. Meier et al.   DIABETES

Beta cell mass in diabetes: a realistic therapeutic target?

(2008) J. J. Meier   DIABETOLOGIA

Expanding human beta cells

(2008) R. Scharfmann   DIABETOLOGIA

A technicolour approach to the connectome

(2008) Jeff W. Lichtman et al.   NATURE REVIEWS NEUROSCIENCE