The epigenetic signature of systemic insulin resistance in obese women

The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes

(2015) I Dahlman et al.   INTERNATIONAL JOURNAL OF OBESITY

DNA methylation, insulin resistance and second-generation antipsychotics in bipolar disorder

(2015) Kyle J Burghardt et al.   Epigenomics

An analysis of DNA methylation in human adipose tissue reveals differential modification of obesity genes before and after gastric bypass and weight loss

(2015) Miles C Benton et al.   GENOME BIOLOGY

Enhanced insulin signaling in density-enhanced phosphatase-1 (DEP-1) knockout mice

(2015) Janine Krüger et al.   Molecular Metabolism

Reference-free cell mixture adjustments in analysis of DNA methylation data

(2014) Eugene Andres Houseman et al.   BIOINFORMATICS

Altered DNA Methylation and Differential Expression of Genes Influencing Metabolism and Inflammation in Adipose Tissue From Subjects With Type 2 Diabetes

(2014) E. Nilsson et al.   DIABETES

Adiposity is associated with DNA methylation profile in adipose tissue

(2014) Golareh Agha et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Differential methylation in visceral adipose tissue of obese men discordant for metabolic disturbances

(2014) Frédéric Guénard et al.   PHYSIOLOGICAL GENOMICS

Epigenome-Wide Association Study of Fasting Measures of Glucose, Insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network Study

(2013) B. Hidalgo et al.   DIABETES

Pathophysiology of Human Visceral Obesity: An Update

(2013) André Tchernof et al.   PHYSIOLOGICAL REVIEWS

Inverse Regulation of Inflammation and Mitochondrial Function in Adipose Tissue Defines Extreme Insulin Sensitivity in Morbidly Obese Patients

(2012) M. Qatanani et al.   DIABETES

Targeted Overexpression of Inducible 6-Phosphofructo-2-kinase in Adipose Tissue Increases Fat Deposition but Protects against Diet-induced Insulin Resistance and Inflammatory Responses

(2012) Yuqing Huo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility

(2012) Lovisa E. Reinius et al.   PLoS One

Global Gene Expression Profiles of Subcutaneous Adipose and Muscle From Glucose-Tolerant, Insulin-Sensitive, and Insulin-Resistant Individuals Matched for BMI

(2011) Steven C. Elbein et al.   DIABETES

Epigenetics

(2011) Jean-Pierre Issa   FEBS LETTERS

Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation

(2010) Michael Spencer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Worsening of Obesity and Metabolic Status Yields Similar Molecular Adaptations in Human Subcutaneous and Visceral Adipose Tissue: Decreased Metabolism and Increased Immune Response

(2010) Eva Klimčáková et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Gender differences in insulin resistance, body composition, and energy balance

(2009) Eliza B. Geer et al.   Gender Medicine

Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

(2009) Madeleine P Ball et al.   NATURE BIOTECHNOLOGY

Epigenetic mechanisms that underpin metabolic and cardiovascular diseases

(2009) Peter D. Gluckman et al.   Nature Reviews Endocrinology

Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity

(2008) Corneliu Henegar et al.   GENOME BIOLOGY