Mir-217 promotes inflammation and fibrosis in high glucose cultured rat glomerular mesangial cells via Sirt1/HIF-1α signaling pathway

SIRT1 reduction causes renal and retinal injury in diabetes through endothelin 1 and transforming growth factor β1

(2015) Rokhsana Mortuza et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Myeloid-specific SIRT1 Deletion Aggravates Hepatic Inflammation and Steatosis in High-fat Diet-fed Mice

(2015) Kyung Eun Kim et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Differential roles of Sirt1 in HIF-1α and HIF-2α mediated hypoxic responses

(2014) Haejin Yoon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chronic pancreatitis and pancreatic cancer demonstrate active epithelial–mesenchymal transition profile, regulated by miR-217-SIRT1 pathway

(2014) Shichang Deng et al.   CANCER LETTERS

Toll-like receptor activation: from renal inflammation to fibrosis

(2014) Wai Han Yiu et al.   Kidney International Supplements

Regulation of TIMP3 in diabetic nephropathy: a role for microRNAs

(2013) Loredana Fiorentino et al.   ACTA DIABETOLOGICA

Anti-aging molecule, Sirt1: a novel therapeutic target for diabetic nephropathy

(2013) Shinji Kume et al.   ARCHIVES OF PHARMACAL RESEARCH

SIRT1 attenuates neointima formation by inhibiting HIF-1α expression in neointimal lesion of a murine wire-injured femoral artery

(2013) Jin U. Bae et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Rho-kinase inhibition prevents the progression of diabetic nephropathy by downregulating hypoxia-inducible factor 1α

(2013) Keiichiro Matoba et al.   KIDNEY INTERNATIONAL

Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes

(2013) Kazuhiro Hasegawa et al.   NATURE MEDICINE

Endothelin-1 promotes vascular endothelial growth factor-dependent angiogenesis in human chondrosarcoma cells

(2013) M-H Wu et al.   ONCOGENE

Resveratrol: Why Is It a Promising Therapy for Chronic Kidney Disease Patients?

(2013) Juliana F. Saldanha et al.   Oxidative Medicine and Cellular Longevity

Smad2-Dependent Downregulation of miR-30 Is Required for TGF-β-Induced Apoptosis in Podocytes

(2013) Shaolin Shi et al.   PLoS One

MicroRNA-217 Promotes Angiogenesis of Human Cytomegalovirus-Infected Endothelial Cells through Downregulation of SIRT1 and FOXO3A

(2013) Shanchao Zhang et al.   PLoS One

Outcome of Acute Renal Injury in Diabetic Mice with Experimental Endotoxemia: Role of Hypoxia-Inducible Factor-1α

(2013) A. Ortega et al.   Journal of Diabetes Research

SIRT1 in Type 2 Diabetes: Mechanisms and Therapeutic Potential

(2013) Munehiro Kitada et al.   Diabetes & Metabolism Journal

MicroRNA-217 Promotes Ethanol-induced Fat Accumulation in Hepatocytes by Down-regulating SIRT1

(2012) Huquan Yin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of SIRT1 Impairs the Accumulation and Transcriptional Activity of HIF-1α Protein under Hypoxic Conditions

(2012) Alexander Laemmle et al.   PLoS One

Tubular Injury in a Rat Model of Type 2 Diabetes Is Prevented by Metformin

(2011) Yumi Takiyama et al.   DIABETES

High glucose activates HIF-1-mediated signal transduction in glomerular mesangial cells through a carbohydrate response element binding protein

(2010) Tsubasa Isoe et al.   KIDNEY INTERNATIONAL

Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α

(2010) Ji-Hong Lim et al.   MOLECULAR CELL

MicroRNA 217 Modulates Endothelial Cell Senescence via Silent Information Regulator 1

(2009) Rossella Menghini et al.   CIRCULATION

Hypoxia-Inducible Factor-1 as Regulator of Angiogenesis in Rheumatoid Arthritis - Therapeutic Implications

(2009) J. Westra et al.   CURRENT MEDICINAL CHEMISTRY