Article
Chemistry, Multidisciplinary
Xiaoya Ding, Yunru Yu, Luoran Shang, Yuanjin Zhao
Summary: With the assistance of histidine, low-viscosity GO mixed polymer solutions can be prepared as printable inks through microfluidic 3D printing technique, forming hydrogel microfibers in histidine solutions. These hydrogel fibers support cell survival, exhibit excellent electrical conductivity, and can sense motion changes, offering a new option for the design and application of 3D printable aqueous GO inks in various fields.
Article
Materials Science, Multidisciplinary
Amit Bandyopadhyay, Susmita Bose, Roger Narayan
Summary: This article reviews the impact of technological development on the manufacturing of biomedical devices and discusses the progress and regulatory issues of 3D printing biomaterials and medical devices.
Review
Engineering, Biomedical
Daphne van der Heide, Gianluca Cidonio, Martin James Stoddart, Matteo D'Este
Summary: 3D printing technology offers a solution to address the issues of material scarcity and safety concerns in bone fracture treatment. Through specific design of biomaterial inks, personalized treatment for patient bone defects can be achieved.
Review
Chemistry, Analytical
Kirsty Muldoon, Yanhua Song, Zeeshan Ahmad, Xing Chen, Ming-Wei Chang
Summary: Three dimensional printing, also known as additive manufacturing, is a rapidly growing process that has applications in various sectors such as electronics, biomedical, pharmaceutical, and tissue engineering. Micro and nano scale printing allows for precise control over design, material, and chemical properties, resulting in high surface area to volume ratios and altered mechanical and physical properties of the products. This review discusses the applications of micro/nano printing technologies such as lithography, inkjet, and electrohydrodynamic printing in the biomedical and electronic fields. The limitations of current micro/nano printing methods, particularly in achieving controlled structures at the required tiny micro and nano scales, are also examined.
Article
Chemistry, Multidisciplinary
Guo-Xiang Zhou, Yan-Ge Yu, Zhi-Hua Yang, De-Chang Jia, Philippe Poulin, Yu Zhou, Jing Zhong
Summary: A universal strategy for 3D printing graphene oxide (GO) complex structures with high alignment and density is proposed. The combination of direct ink writing and constrained drying allows for the compaction and alignment of GO, while maintaining the structure's uniformity through controlled shrinkage. The study also discovers a gradient of porosity naturally formed across the thickness direction at the corner, enabling the 3D printing of humidity sensitive GO-based soft robotics.
Article
Materials Science, Biomaterials
Xiaoye Yu, Guanghui Li, Yikan Zheng, Jingming Gao, Ye Fu, Qunsong Wang, Lei Huang, Xiaogang Pan, Jiandong Ding
Summary: This study explores a modern treatment for malalignment of teeth using clear polymeric aligners fabricated by molding polyurethane films on 3D-printed personalized dental models. Through various tests and experiments, the biocompatibility and efficacy of the clear aligners were confirmed, leading to successful clinical treatments.
REGENERATIVE BIOMATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Amit Bandyopadhyay, Sourabh Ghosh, Aldo R. Boccaccini, Susmita BosenAff
Summary: 3D printing, also known as additive manufacturing, has become a transformative technology platform impacting various disciplines. This special issue presents perspectives from scientists, engineers, and medical professionals on 3D printing of biomaterials and biomedical devices and covers a wide range of research topics involving different materials and printing processes.
JOURNAL OF MATERIALS RESEARCH
(2021)
Review
Biophysics
Bankole I. Oladapo, S. Abolfazl Zahedi, Sikiru O. Ismail, Francis T. Omigbodun
Summary: This research showcases the potential of PEEK material in medical applications, emphasizing its biological macromolecular behaviors as a bone implant material and the optimal 3D printing process for PEEK and CHAp in medical applications.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Materials Science, Multidisciplinary
Dominic J. Wales, Meysam Keshavarz, Carmel Howe, Eric Yeatman
Summary: In this study, we demonstrate the feasibility of 3D printing with POMaC, a bio-adhesive material with great potential for implantable biomedical devices. By optimizing the parameters, we successfully printed biomaterial copolymers consisting of POMaC and PEGDA, achieving tunable mechanical properties. The biocompatibility of the copolymers was also verified.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Zhiqiang Liang, Yonggang Yao, Bo Jiang, Xizheng Wang, Hua Xie, Miaolun Jiao, Chu Liang, Haiyu Qiao, Dylan Kline, Michael R. Zachariah, Liangbing Hu
Summary: The study introduces a novel method of small-scale heating using 3D printed RGO probes, achieving precise heating with high spatial and temporal resolutions. The research demonstrates the selective synthesis of metal nanoparticles such as platinum and silver on nano-carbon substrates, which is not achievable by traditional steady-state heating.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Jingzhuo Zhou, Xin Wu, Yan Chen, Chuang Yang, Rui Yang, Junyang Tan, Yilun Liu, Ling Qiu, Hui-Ming Cheng
Summary: Using graphene as a model building block, the fabrication of multiscale structures with tailorable features spanning seven orders of magnitude in size is achieved by a 3D printed template-directed assembly method. The structures demonstrate extraordinary properties such as ultralow density, ultrahigh stiffness, and compressibility.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Pharmacology & Pharmacy
Austin J. Bow, Thomas J. Masi, Madhu S. Dhar
Summary: In this study, established rat dental pulp stem cell (rDPSC) populations were used to assess functionalized polycaprolactone (PCL) constructs, demonstrating good cell surface coverage in vitro. The modified rGO-functionalized PCL constructs were shown to be a versatile platform for bone tissue engineering applications.
Review
Pharmacology & Pharmacy
Amber F. MacDonald, Meaghan E. Harley-Troxell, Steven D. Newby, Madhu S. Dhar
Summary: This article summarizes the application of graphene-based materials in tissue engineering, with a focus on bone tissue engineering. It discusses the need for developing 3D graphene scaffolds and introduces the current manufacturing techniques and limitations.
Article
Chemistry, Multidisciplinary
Yuchao Wu, Paul A. Advincula, Oliver Giraldo-Londono, Yukai Yu, Yunchao Xie, Zhenru Chen, Guoliang Huang, James M. Tour, Jian Lin
Summary: This article discusses the sustainability of 3D printing in terms of using renewable inks, recycling printed products, and energy-and materials-saving applications. By developing renewable inks and materials, recycling printed products, and utilizing them for other purposes, the article demonstrates sustainable management of the entire life cycle of 3D printing, inspiring further development in this field.
Article
Engineering, Manufacturing
Elias Madadian, Emad Naseri, Ryan Legault, Ali Ahmadi
Summary: This article introduces a method to develop 3D printable hybrid sodium alginate and albumin foam, crosslinked with calcium chloride mist. Highly porous structures are produced without the need for further postprocessing. The printed foams show excellent lift-off and water absorption properties, making it beneficial for the development of wound dressing.
3D PRINTING AND ADDITIVE MANUFACTURING
(2023)
Article
Veterinary Sciences
Federico Longo, Parastoo Memarian, Sebastian Christoph Knell, Barbara Contiero, Antonio Pozzi
Summary: This study aimed to determine cutoff values for identifying abnormal femoral trochlea morphology in small and medium/large breed dogs with and without medial patellar luxation. The results showed that dogs without MPL had a deeper femoral trochlear groove than MPL dogs, and small breed dogs had a shallower groove than medium/large breed dogs.
VETERINARY SURGERY
(2023)
Article
Chemistry, Physical
Riccardo Sponchiado, Stefano Rosso, Pierandrea Dal Fabbro, Luca Grigolato, Hamada Elsayed, Enrico Bernardo, Mattia Maltauro, Francesca Uccheddu, Roberto Meneghello, Gianmaria Concheri, Gianpaolo Savio
Summary: Material extrusion additive manufacturing allows for combining multiple materials in the same nozzle, known as material coextrusion, which enables the creation of materials with a wide range of properties. This study investigates the behavior of two compatible material pairs and proposes a model to describe material distribution. The results from analytical and numerical models were validated through experimental tests, providing valuable insights for designers and contributing to additive manufacturing research.
Article
Materials Science, Biomaterials
Yasar Kemal Erdogan, Batur Ercan
Summary: Surface modifications with nanostructures can enhance the cellular interactions and prevent biofilm synthesis on 316L stainless steel implants. In this study, arrays of nanodimples were fabricated on the 316L SS surfaces by anodic oxidation, which increased surface area and improved osteoblast viability and functions. The nanodimple surfaces also exhibited significant reduction in Staphylococcus aureus and Pseudomonas aeruginosa biofilm synthesis.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Article
Biochemistry & Molecular Biology
Federica Zanotti, Ilaria Zanolla, Martina Trentini, Elena Tiengo, Tommaso Pusceddu, Danilo Licastro, Margherita Degasperi, Sara Leo, Elena Tremoli, Letizia Ferroni, Barbara Zavan
Summary: Small extracellular vesicles derived from mesenchymal stem cells (MSCs), treated with the stabilizer deferoxamine mesylate (DFO), induce molecular pathways and biological processes linked to proliferation and angiogenesis in recipient endothelial cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Editorial Material
Biochemistry & Molecular Biology
Marco Tatullo, Barbara Zavan, Adriano Piattelli
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Engineering, Multidisciplinary
Annj Zamuner, Elena Zeni, Hamada Elsayed, Michele Di Foggia, Paola Taddei, Antonella Pasquato, Lucy Di Silvio, Enrico Bernardo, Paola Brun, Monica Dettin
Summary: Hardystonite-based bioceramic foams were easily obtained via thermal treatment of silicone resins and reactive oxide fillers in air. By incorporating strontium oxide and magnesium oxide precursors, a complex solid solution with superior biocompatibility and bioactivity properties can be obtained.
Article
Medicine, General & Internal
Michele Riccio, Elena Bondioli, Letizia Senesi, Nicola Zingaretti, Paolo Gargiulo, Francesco De Francesco, Pier Camillo Parodi, Barbara Zavan
Summary: This study investigated the application of fragmented dermo-epidermal units (FdeU) for wound healing, using a novel medical device to acquire the tissue. The results showed that FdeU acted as a slow-released natural scaffold and continuously delivered growth factors, promoting the proliferation and regenerative process of resident cells. Clinical evaluation confirmed the effectiveness of FdeU in wound healing. The study recommended FdeU as a favorable tool with growth-promoting potential for wound healing.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Materials Science, Multidisciplinary
Cengiz Bagci, Giulia Tameni, Hamada Elsayed, Enrico Bernardo
Summary: The current climate emergency leads to a reduction in extracting virgin raw materials and promotes circular economy. By combining alkali activation of unemployed fraction of grey tuff with glass waste, sustainable construction materials can be produced.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Nanoscience & Nanotechnology
Yagmur Goctu, Cagatay M. Oral, Batur Ercan
Summary: This study introduces selenite-incorporated magnesium-stabilized amorphous calcium carbonate (ACMC) nanoparticles as a sustainable antibacterial material. It demonstrates that selenite ions can be incorporated into ACMC nanoparticles while preserving the amorphous structure. The antibacterial activity analysis shows that selenite-incorporated ACMC nanoparticles significantly reduce the growth of various bacteria strains, and the antibacterial activity increases with an increase in the amount of incorporated selenite.
ACS APPLIED NANO MATERIALS
(2023)
Article
Multidisciplinary Sciences
Diana Lago, Jozef Kraxner, Dusan Galusek, Enrico Bernardo
Summary: A porous membrane with a consolidated structure was successfully developed by alkali activation of pharmaceutical boro-aluminosilicate glass powders in diluted NaOH and KOH solutions. The binding phase in the membrane showed good stability against immersion in boiling water and acidic solutions. Copper adsorption tests demonstrated that the washed membranes exhibited an adsorption efficiency of over 60% at pH = 5, while the efficiency decreased at pH = 2 due to the presence of H3O+ ions. The membranes were further densified through viscous flow sintering at 700 degrees C to ensure immobilization of copper ions. Leaching tests confirmed the efficiency of the process. Evaluation: 8.5/10.
Article
Materials Science, Ceramics
Fulden Dogrul, Vera Bednarzig, Hamada Elsayed, Liliana Liverani, Dusan Galusek, Enrico Bernardo, Aldo R. Boccaccini
Summary: In this study, reticulated akermanite 3D scaffolds were fabricated using direct ink writing technology, and different additives were added to influence the mechanical properties of the scaffolds. It was found that the two additives did not lead to significant differences in biological response, and the fabricated ceramics showed in-vitro bioactivity and antibacterial activity.
Article
Dentistry, Oral Surgery & Medicine
Giovanna Iezzi, Barbara Zavan, Morena Petrini, Letizia Ferroni, Tania Vanessa Pierfelice, Ugo D'Amora, Alfredo Ronca, Emira D'Amico, Carlo Mangano
Summary: This study characterized the surface topography and evaluated the biological responses of various cells to a novel 3D-printed dental implant. The surface of the implant showed a highly interconnected porous architecture and roughness, leading to good adhesion and growth of human oral osteoblasts, gingival fibroblasts, mesenchymal stem cells, and monocytes. These findings suggest that this 3D-printed implant has excellent potential for clinical applications.
JOURNAL OF DENTISTRY
(2024)
Article
Chemistry, Multidisciplinary
Muhammad Saqib, Batur Ercan, E. Yegan Erdem
Summary: A novel microfluidic device is reported for the synthesis of magnetically anisotropic Janus particles. The device enables control over the size distribution of the particles through droplet generation, magnetic separation, and ultraviolet polymerization. The synthesized particles exhibit a monodisperse size distribution and anisotropic magnetic properties, allowing them to rotate about their own axes in the presence of an external magnetic field.
Article
Multidisciplinary Sciences
Anna Mazzi, Michela Sciarrone, Enrico Bernardo
Summary: Using the alkali activation process to produce glass foam from waste glass can avoid the drawbacks in the purity of starting feedstock and has the potential to reduce environmental impacts. This study conducted a life cycle assessment to analyze the environmental profile of glass foam production, considering transportation, production process, and end-of-life stages. The results show that the production phase has the greatest contribution to overall environmental impacts, with electricity consumption and surfactant usage being the main factors. Sensitivity analyses suggest that minimizing distances in the supply chain and using renewable energy sources can significantly improve the environmental profile.
