UBAC1/KPC2 Regulates TLR3 Signaling in Human Keratinocytes through Functional Interaction with the CARD14/CARMA2sh-TANK Complex

MALT 1 targeting suppresses CARD 14‐induced psoriatic dermatitis in mice

(2020) Elien Van Nuffel et al.   EMBO REPORTS

Regulation and dysregulation of CARD14 signalling and its physiological consequences in inflammatory skin disease

(2020) Mark Mellett   CELLULAR IMMUNOLOGY

CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation

(2020) Joan Manils et al.   eLife

CARD14/CARMA2 sh and TANK differentially regulate poly(I:C)–induced inflammatory reaction in keratinocytes

(2019) Serena Voccola et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Gain of function p.E138A alteration in Card14 leads to psoriasiform skin inflammation and implicates genetic modifiers in disease severity

(2019) John P. Sundberg et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

CARMA3 Mediates Allergic Lung Inflammation in Response to Alternaria alternata

(2018) Benjamin Causton et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Gain-of-Function Mutation of Card14 Leads to Spontaneous Psoriasis-like Skin Inflammation through Enhanced Keratinocyte Response to IL-17A

(2018) Mingchao Wang et al.   IMMUNITY

CARD14 Gain-of-Function Mutation Alone Is Sufficient to Drive IL-23/IL-17–Mediated Psoriasiform Skin Inflammation In Vivo

(2018) Mark Mellett et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

CARD14/CARMA2 Signaling and its Role in Inflammatory Skin Disorders

(2018) Tiziana Zotti et al.   Frontiers in Immunology

The E3 Ubiquitin Ligase RNF7 Negatively Regulates CARD14/CARMA2sh Signaling

(2017) Gianluca Telesio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CARD14-Mediated Activation of Paracaspase MALT1 in Keratinocytes: Implications for Psoriasis

(2017) Elien Van Nuffel et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

CARMA2sh and ULK2 control pathogen-associated molecular patterns recognition in human keratinocytes: psoriasis-linked CARMA2sh mutants escape ULK2 censorship

(2017) Ivan Scudiero et al.   Cell Death & Disease

The paracaspase MALT1 mediates CARD14‐induced signaling in keratinocytes

(2016) Inna S Afonina et al.   EMBO REPORTS

Ubiquitin chain diversity at a glance

(2016) Masato Akutsu et al.   JOURNAL OF CELL SCIENCE

CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection

(2016) Changying Jiang et al.   Cell Reports

Activating CARD14 Mutations Are Associated with Generalized Pustular Psoriasis but Rarely Account for Familial Recurrence in Psoriasis Vulgaris

(2015) Dorottya M. Berki et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Dishevelled, EGL-10 and Pleckstrin (DEP) Domain-Containing Protein DEPDC7 Binds to CARMA2 and CARMA3 Proteins, and Regulates NF-κB Activation

(2014) Egildo Luca D′ Andrea et al.   PLoS One

The Three CARMA Sisters: So Different, So Similar: A Portrait of the Three CARMA Proteins and Their Involvement in Human Disorders

(2013) Ivan Scudiero et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Structural Architecture of the CARMA1/Bcl10/MALT1 Signalosome: Nucleation-Induced Filamentous Assembly

(2013) Qi Qiao et al.   MOLECULAR CELL

PSORS2 Is Due to Mutations in CARD14

(2012) Catherine T. Jordan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Rare and Common Variants in CARD14, Encoding an Epidermal Regulator of NF-kappaB, in Psoriasis

(2012) Catherine T. Jordan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

K63-Linked Ubiquitination in Kinase Activation and Cancer

(2012) Guocan Wang et al.   Frontiers in Oncology

Alternative splicing of CARMA2/CARD14 transcripts generates protein variants with differential effect on NF-κB activation and endoplasmic reticulum stress-induced cell death

(2011) Ivan Scudiero et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Role of Ubiquitin in NF-κB Regulatory Pathways

(2009) Brian Skaug et al.   Annual Review of Biochemistry

Epidermal homeostasis: a balancing act of stem cells in the skin

(2009) Cédric Blanpain et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TLR3: Interferon induction by double-stranded RNA including poly(I:C)☆

(2008) M MATSUMOTO et al.   ADVANCED DRUG DELIVERY REVIEWS