Angiotensin-converting enzymes (ACE, ACE2) gene variants and COVID-19 outcome

Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2

(2020) Renhong Yan et al.   SCIENCE

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

(2020)   Nature Microbiology

Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations

(2020) Yanan Cao et al.   Cell Discovery

COVID-19 infections are also affected by human ACE1 D/I polymorphism

(2020) Joris R. Delanghe et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Circulating plasma concentrations of angiotensin-converting enzyme 2 in men and women with heart failure and effects of renin–angiotensin–aldosterone inhibitors

(2020) Iziah E Sama et al.   EUROPEAN HEART JOURNAL

Understanding the Renin-Angiotensin-Aldosterone-SARS-CoV-Axis: A Comprehensive Review

(2020) Nicholas E. Ingraham et al.   EUROPEAN RESPIRATORY JOURNAL

ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome

(2020) Christian A. Devaux et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

Structural basis of receptor recognition by SARS-CoV-2

(2020) Jian Shang et al.   NATURE

The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice

(2020) Linlin Bao et al.   NATURE

Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

(2020) Tao Guo et al.   JAMA Cardiology

Association of Coronavirus Disease 2019 (COVID-19) With Myocardial Injury and Mortality

(2020) Robert O. Bonow et al.   JAMA Cardiology

Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China

(2020) Shaobo Shi et al.   JAMA Cardiology

Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: A systematic review and meta-analysis

(2020) Leiwen Fu et al.   JOURNAL OF INFECTION

Angiotensin-converting enzymes in acute respiratory distress syndrome

(2019) Filippo Annoni et al.   INTENSIVE CARE MEDICINE

Association of ACE2 genetic polymorphisms with hypertension-related target organ damages in south Xinjiang

(2018) Yi Luo et al.   HYPERTENSION RESEARCH

TheACE2G8790A Polymorphism: Involvement in Type 2 Diabetes Mellitus Combined with Cerebral Stroke

(2016) Yan-Hui Wu et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Angiotensin II regulates ACE and ACE2 in neurons through p38 mitogen-activated protein kinase and extracellular signal-regulated kinase 1/2 signaling

(2013) Liang Xiao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cardioprotective Effects Mediated by Angiotensin II Type 1 Receptor Blockade and Enhancing Angiotensin 1-7 in Experimental Heart Failure in Angiotensin-Converting Enzyme 2–Null Mice

(2012) Vaibhav B. Patel et al.   HYPERTENSION

ACE2 gene polymorphism and essential hypertension: an updated meta-analysis involving 11,051 subjects

(2012) Na Lu et al.   MOLECULAR BIOLOGY REPORTS

Functional polymorphisms in genes of the Angiotensin and Serotonin systems and risk of hypertrophic cardiomyopathy: AT1R as a potential modifier

(2010) Eliecer Coto et al.   Journal of Translational Medicine

SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS

(2009) G. Y. Oudit et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Angiotensin II Up-Regulates Angiotensin I-Converting Enzyme (ACE), but Down-Regulates ACE2 via the AT1-ERK/p38 MAP Kinase Pathway

(2008) Vijay Koka et al.   AMERICAN JOURNAL OF PATHOLOGY

Genetic variation in angiotensin-converting enzyme 2 gene is associated with extent of left ventricular hypertrophy in hypertrophic cardiomyopathy

(2008) Lize van der Merwe et al.   HUMAN GENETICS