Metabotropic glutamate receptor 5 responses dictate differentiation of neural progenitors to NMDA-responsive cells in fragile X syndrome

Mavoglurant in fragile X syndrome: Results of two randomized, double-blind, placebo-controlled trials

(2016) Elizabeth Berry-Kravis et al.   Science Translational Medicine

Functional Deficiencies in Fragile X Neurons Derived from Human Embryonic Stem Cells

(2015) M. Telias et al.   JOURNAL OF NEUROSCIENCE

Molecular Mechanisms Regulating Impaired Neurogenesis of Fragile X Syndrome Human Embryonic Stem Cells

(2015) Michael Telias et al.   STEM CELLS AND DEVELOPMENT

Neural progenitors, neurogenesis and the evolution of the neocortex

(2014) M. Florio et al.   DEVELOPMENT

Tissue Plasminogen Activator Contributes to Alterations of Neuronal Migration and Activity-Dependent Responses in Fragile X Mice

(2014) V. S. Achuta et al.   JOURNAL OF NEUROSCIENCE

Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1 −/y mice

(2014) Yu Zhang et al.   NATURE NEUROSCIENCE

iPSC-Derived Forebrain Neurons from FXS Individuals Show Defects in Initial Neurite Outgrowth

(2014) Matthew E. Doers et al.   STEM CELLS AND DEVELOPMENT

Effect of glutamate receptor antagonists on migrating neural progenitor cells

(2013) Linda C. Jansson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Precursor Diversity and Complexity of Lineage Relationships in the Outer Subventricular Zone of the Primate

(2013) Marion Betizeau et al.   NEURON

Mitotic spindle orientation predicts outer radial glial cell generation in human neocortex

(2013) Bridget E. LaMonica et al.   Nature Communications

Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?

(2013) Talakad G Lohith et al.   Molecular Autism

The Pathophysiology of Fragile X (and What It Teaches Us about Synapses)

(2012) Asha L. Bhakar et al.   Annual Review of Neuroscience

New perspectives on the biology of fragile X syndrome

(2012) Tao Wang et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Neural differentiation of fragile X human embryonic stem cells reveals abnormal patterns of development despite successful neurogenesis

(2012) Michael Telias et al.   DEVELOPMENTAL BIOLOGY

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

(2011) Jennifer C. Darnell et al.   CELL

Heads-up: New roles for the fragile X mental retardation protein in neural stem and progenitor cells

(2011) Matthew A. Callan et al.   GENESIS

Impaired inhibitory control of cortical synchronization in fragile X syndrome

(2011) Scott M. Paluszkiewicz et al.   JOURNAL OF NEUROPHYSIOLOGY

FMRP Regulates the Transition from Radial Glial Cells to Intermediate Progenitor Cells during Neocortical Development

(2011) R. Saffary et al.   JOURNAL OF NEUROSCIENCE

Ablation of Fmrp in adult neural stem cells disrupts hippocampus-dependent learning

(2011) Weixiang Guo et al.   NATURE MEDICINE

Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripotent Stem Cell Models of Fragile X Syndrome

(2011) Steven D. Sheridan et al.   PLoS One

Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of subpallial GABAergic interneurons

(2010) A. Sessa et al.   GENES & DEVELOPMENT

Neurogenic radial glia in the outer subventricular zone of human neocortex

(2010) David V. Hansen et al.   NATURE

Functional rescue of excitatory synaptic transmission in the developing hippocampus in Fmr1-KO mouse

(2010) Rhiannon M. Meredith et al.   NEUROBIOLOGY OF DISEASE

Critical Period Plasticity Is Disrupted in the Barrel Cortex of Fmr1 Knockout Mice

(2010) Emily G. Harlow et al.   NEURON

Fragile X and autism: Intertwined at the molecular level leading to targeted treatments

(2010) Randi Hagerman et al.   Molecular Autism

Glutamate and Neurotrophic Factors in Neuronal Plasticity and Disease

(2009) Mark P. Mattson   Annals of the New York Academy of Sciences

The Glial Nature of Embryonic and Adult Neural Stem Cells

(2009) Arnold Kriegstein et al.   Annual Review of Neuroscience

Neurogenesis Mediated by γ-Aminobutyric Acid and Glutamate Signaling

(2009) Noritaka Nakamichi et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Distinct behaviors of neural stem and progenitor cells underlie cortical neurogenesis

(2008) Stephen C. Noctor et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Imbalance of Neocortical Excitation and Inhibition and Altered UP States Reflect Network Hyperexcitability in the Mouse Model of Fragile X Syndrome

(2008) Jay R. Gibson et al.   JOURNAL OF NEUROPHYSIOLOGY

Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome

(2008) Gül Dölen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Synaptic ionotropic glutamate receptors and plasticity are developmentally altered in the CA1 field ofFmr1knockout mice

(2008) Yair Pilpel et al.   JOURNAL OF PHYSIOLOGY-LONDON

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

(2008) Femke M.S. de Vrij et al.   NEUROBIOLOGY OF DISEASE

Aberrant differentiation of glutamatergic cells in neocortex of mouse model for fragile X syndrome

(2008) Topi A. Tervonen et al.   NEUROBIOLOGY OF DISEASE

Metabotropic Glutamate 1 Receptor: Current Concepts and Perspectives

(2008) F. Ferraguti et al.   PHARMACOLOGICAL REVIEWS

The role of ATP signaling in the migration of intermediate neuronal progenitors to the neocortical subventricular zone

(2008) X. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA