The tumor suppressor LATS2 reduces v‐Src‐induced membrane blebs in a kinase activity‐independent manner

The tyrosine kinase v-Src causes mitotic slippage by phosphorylating an inhibitory tyrosine residue of Cdk1

(2018) Maria Horiuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytokinesis Failure Leading to Chromosome Instability in v-Src-Induced Oncogenesis

(2017) Yuji Nakayama et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

β1 integrin–dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin

(2017) Hiba Sabra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of Hippo pathway regulation

(2016) Zhipeng Meng et al.   GENES & DEVELOPMENT

αE-catenin inhibits a Src–YAP1 oncogenic module that couples tyrosine kinases and the effector of Hippo signaling pathway

(2016) Peng Li et al.   GENES & DEVELOPMENT

v-Src Causes Chromosome Bridges in a Caffeine-Sensitive Manner by Generating DNA Damage

(2016) Masayoshi Ikeuchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A RhoA and Rnd3 cycle regulates actin reassembly during membrane blebbing

(2016) Kana Aoki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An evolutionarily conserved negative feedback mechanism in the Hippo pathway reflects functional difference between LATS1 and LATS2

(2016) Gun-Soo Park et al.   Oncotarget

Protective role for lipid modifications of Src-family kinases against chromosome missegregation

(2016) Takuya Honda et al.   Scientific Reports

Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway

(2015) Youjun Li et al.   CELL RESEARCH

Adhesion to fibronectin regulates Hippo signaling via the FAK–Src–PI3K pathway

(2015) Nam-Gyun Kim et al.   JOURNAL OF CELL BIOLOGY

Cytokinesis Failure Triggers Hippo Tumor Suppressor Pathway Activation

(2014) Neil J. Ganem et al.   CELL

Mutation analysis of large tumor suppressor genes LATS1 and LATS2 supports a tumor suppressor role in human cancer

(2014) Tian Yu et al.   Protein & Cell

Spatial Organization of Hippo Signaling at the Plasma Membrane Mediated by the Tumor Suppressor Merlin/NF2

(2013) Feng Yin et al.   CELL

v-Src causes delocalization of Mklp1, Aurora B, and INCENP from the spindle midzone during cytokinesis failure

(2013) Shuhei Soeda et al.   EXPERIMENTAL CELL RESEARCH

Phosphorylation of Angiomotin by Lats1/2 Kinases Inhibits F-actin Binding, Cell Migration, and Angiogenesis

(2013) Xiaoming Dai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LATS2 Suppresses Oncogenic Wnt Signaling by Disrupting β-Catenin/BCL9 Interaction

(2013) Jiong Li et al.   Cell Reports

Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics

(2012) Y Kanda   BONE MARROW TRANSPLANTATION

The Tumor Suppressor Merlin Controls Growth in Its Open State, and Phosphorylation Converts It to a Less-Active More-Closed State

(2012) Ifat Sher et al.   DEVELOPMENTAL CELL

c-Src but Not Fyn Promotes Proper Spindle Orientation in Early Prometaphase

(2012) Yuji Nakayama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

KIBRA Regulates Hippo Signaling Activity via Interactions with Large Tumor Suppressor Kinases

(2011) Ling Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor

(2011) Murugan Paramasivam et al.   MOLECULAR BIOLOGY OF THE CELL

A public genome-scale lentiviral expression library of human ORFs

(2011) Xiaoping Yang et al.   NATURE METHODS

14-3-3 Proteins: Diverse functions in cell proliferation and cancer progression

(2011) Alyson K. Freeman et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Phosphorylation of Trask by Src Kinases Inhibits Integrin Clustering and Functions in Exclusion with Focal Adhesion Signaling

(2010) D. S. Spassov et al.   MOLECULAR AND CELLULAR BIOLOGY

A molecular network for de novo generation of the apical surface and lumen

(2010) David M. Bryant et al.   NATURE CELL BIOLOGY

Defining the Human Deubiquitinating Enzyme Interaction Landscape

(2009) Mathew E. Sowa et al.   CELL

Tumor-suppression functions of merlin are independent of its role as an organizer of the actin cytoskeleton in Schwann cells

(2009) D. Lallemand et al.   JOURNAL OF CELL SCIENCE

Src-Induced Disassembly of Adherens Junctions Requires Localized Phosphorylation and Degradation of the Rac Activator Tiam1

(2009) Simon A. Woodcock et al.   MOLECULAR CELL

A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells

(2009) Eric Campeau et al.   PLoS One

Merlin and the ERM proteins – regulators of receptor distribution and signaling at the cell cortex

(2009) Andrea I. McClatchey et al.   TRENDS IN CELL BIOLOGY

The Diaphanous-related Formin FHOD1 Associates with ROCK1 and Promotes Src-dependent Plasma Membrane Blebbing

(2008) Sebastian Hannemann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell motility through plasma membrane blebbing

(2008) Oliver T. Fackler et al.   JOURNAL OF CELL BIOLOGY

Anin vitro recombination method to convert restriction- and ligation-independent expression vectors

(2007) Feng Guo et al.   Biotechnology Journal