Targeting inhibition of CCR5 on improving obesity-associated insulin resistance and impairment of pancreatic insulin secretion in high fat-fed rodent models

Importance of PLC-Dependent PI3K/AKT and AMPK Signaling in RANTES/CCR5 Mediated Macrophage Chemotaxis

(2018) Hung-Che Chien   CHINESE JOURNAL OF PHYSIOLOGY

CCR2 and CCR5 promote diclofenac-induced hepatotoxicity in mice

(2018) Zhanke He et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Importance of NADPH oxidase-mediated redox signaling in the detrimental effect of CRP on pancreatic insulin secretion

(2017) Pei-Chi Chan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Maraviroc Reduces Arterial Stiffness in PI-Treated HIV-infected Patients

(2016) Stefania Piconi et al.   Scientific Reports

Silencing CCR2 in Macrophages Alleviates Adipose Tissue Inflammation and the Associated Metabolic Syndrome in Dietary Obese Mice

(2016) Jongkil Kim et al.   Molecular Therapy-Nucleic Acids

Macrophage recruitment in obese adipose tissue

(2015) Y. Bai et al.   Obesity Reviews

β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment

(2014) Philippe A. Halban et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Loss of CCR5 results in glucose intolerance in diet-induced obese mice

(2013) Arion Kennedy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

CCR5 Plays a Critical Role in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Both Macrophage Recruitment and M1/M2 Status

(2012) H. Kitade et al.   DIABETES

The Chemokine CCL5 Regulates Glucose Uptake and AMP Kinase Signaling in Activated T Cells to Facilitate Chemotaxis

(2012) Olivia Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CCR2 and CCR5 chemokine receptors differentially influence the development of autoimmune diabetes in the NOD mouse

(2010) Michelle Solomon et al.   AUTOIMMUNITY

The beta cell lesion in type 2 diabetes: there has to be a primary functional abnormality

(2009) S. E. Kahn et al.   DIABETOLOGIA

CCL5 increases lung cancer migration via PI3K, Akt and NF-κB pathways

(2008) Chun-Yin Huang et al.   BIOCHEMICAL PHARMACOLOGY

Glucolipotoxicity: Fuel Excess and β-Cell Dysfunction

(2008) Vincent Poitout et al.   ENDOCRINE REVIEWS

Induction of copper/zinc-superoxide dismutase by CCL5/CCR5 activation causes tumour necrosis factor-α and reactive oxygen species production in macrophages

(2008) Lei Qiu et al.   IMMUNOLOGY