Comparison of co-former performance in co-amorphous formulations: Single amino acids, amino acid physical mixtures, amino acid salts and dipeptides as co-formers

Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

(2019) Ben J. Boyd et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Organic acids as co-formers for co-amorphous systems - influence of variation in molar ratio on the physicochemical properties of the co-amorphous systems

(2018) Wenqi Wu et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The natural bile acid surfactant sodium taurocholate (NaTC) as a coformer in coamorphous systems: Enhanced physical stability and dissolution behavior of coamorphous drug-NaTc systems

(2018) Katarzyna Gniado et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

On the role of salt formation and structural similarity of co-formers in co-amorphous drug delivery systems

(2018) Wenqi Wu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugs

(2018) Eric Ofosu Kissi et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Physical Stability and Dissolution Behavior of Ketoconazole–Organic Acid Coamorphous Systems

(2018) Michelle Fung et al.   MOLECULAR PHARMACEUTICS

Drug-Excipient Interactions: Effect on Molecular Mobility and Physical Stability of Ketoconazole–Organic Acid Coamorphous Systems

(2018) Michelle H. Fung et al.   MOLECULAR PHARMACEUTICS

Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and l-Arginine

(2018) Hiroshi Ueda et al.   MOLECULAR PHARMACEUTICS

Aspartame as a co-former in co-amorphous systems

(2018) Wenqi Wu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Dipeptides as co-formers in co-amorphous systems

(2018) Wenqi Wu et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Co-former selection for co-amorphous drug-amino acid formulations

(2018) Georgia Kasten et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Influence of preparation pathway on the glass forming ability

(2017) Lasse Ingerslev Blaabjerg et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Development of a screening method for co-amorphous formulations of drugs and amino acids

(2016) Georgia Kasten et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Co amorphous systems: A product development perspective

(2016) Rahul B Chavan et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Amino acids as co-amorphous excipients for tackling the poor aqueous solubility of valsartan

(2016) Ying Huang et al.   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

Preparation and characterization of spray-dried co-amorphous drug-amino acid salts

(2015) Katrine Tarp Jensen et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Formation Mechanism of Coamorphous Drug–Amino Acid Mixtures

(2015) Katrine Tarp Jensen et al.   MOLECULAR PHARMACEUTICS

Improving Co-Amorphous Drug Formulations by the Addition of the Highly Water Soluble Amino Acid, Proline

(2014) Katrine Jensen et al.   Pharmaceutics

Amino acids as co-amorphous stabilizers for poorly water soluble drugs – Part 1: Preparation, stability and dissolution enhancement

(2013) Korbinian Löbmann et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Amino acids as co-amorphous stabilizers for poorly water-soluble drugs – Part 2: Molecular interactions

(2013) Korbinian Löbmann et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Amorphous solid dispersions and nano-crystal technologies for poorly water-soluble drug delivery

(2013) Chris Brough et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions

(2012) Korbinian Löbmann et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Emerging trends in the stabilization of amorphous drugs

(2012) Riikka Laitinen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Solubility Advantage of Amorphous Drugs and Pharmaceutical Cocrystals

(2011) N. Jagadeesh Babu et al.   CRYSTAL GROWTH & DESIGN

Coamorphous Drug Systems: Enhanced Physical Stability and Dissolution Rate of Indomethacin and Naproxen

(2011) Korbinian Löbmann et al.   MOLECULAR PHARMACEUTICS

Quantitative Determination of Hydrate Content of Theophylline Powder by Chemometric X-ray Powder Diffraction Analysis

(2010) Makoto Otsuka et al.   AAPS PHARMSCITECH

Pharmaceutical applications of cyclodextrins: basic science and product development

(2010) Thorsteinn Loftsson et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Enhanced dissolution rate and synchronized release of drugs in binary systems through formulation: Amorphous naproxen–cimetidine mixtures prepared by mechanical activation

(2009) Morten Allesø et al.   JOURNAL OF CONTROLLED RELEASE

Local Mobility in Amorphous Pharmaceuticals—Characterization and Implications on Stability

(2009) Sisir Bhattacharya et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A Standardized Mini Paddle Apparatus as an Alternative to the Standard Paddle

(2008) Sandra Klein et al.   AAPS PHARMSCITECH

Intermolecular contacts influencing the conformational and geometric features of the pharmaceutically preferred mebendazole polymorph C

(2008) Felipe T. Martins et al.   JOURNAL OF PHARMACEUTICAL SCIENCES