Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Annan Zhang, Huiyuan Zhang, Xin Zhou, Zhongwu Li, Nan Li
Summary: A 52-year-old man presenting with right lower chest wall pain for a month was found to have a subpleural solitary fibrous tumor through Ga-68-DOTA-FAPI-04 PET/CT imaging. This case demonstrated the excellent tumor affinity of Ga-68-DOTA-FAPI-04 for solitary fibrous tumors of the pleura.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Haojun Chen, Liang Zhao, Dan Ruan, Yizhen Pang, Bing Hao, Yaqing Dai, Xiurong Wu, Wei Guo, Chunlei Fan, Jingxun Wu, Weipeng Huang, Qin Lin, Long Sun, Hua Wu
Summary: This prospective study evaluated the potential usefulness of [Ga-68]Ga-DOTA-FAPI-04 positron emission tomography/computed tomography (PET/CT) in oncological evaluation of patients with inconclusive [F-18]FDG PET/CT findings. The study found that [Ga-68]Ga-DOTA-FAPI-04 may have a complementary role in discriminating mass lesions on conventional imaging, locating unknown primary sites in biopsy-proven metastatic malignancy, modifying tumor staging, and detecting suspected disease recurrence. However, caution should be exercised when interpreting [Ga-68]Ga-DOTA-FAPI-04 PET/CT images in tumors complicated with inflammation.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Rong Lin, Zefang Lin, Zhenying Chen, Shan Zheng, Jiaying Zhang, Jie Zang, Weibing Miao
Summary: This study compared the performance of [Ga-68]Ga-DOTA-FAPI-04 and [F-18]FDG PET/CT in evaluating gastric cancer. The results showed that [Ga-68]Ga-DOTA-FAPI-04 PET/CT outperformed [F-18]FDG PET/CT in detecting peritoneal, abdominal lymph node, and bone metastases. Additionally, [Ga-68]Ga-DOTA-FAPI-04 PET/CT provided more valuable information for patients with recurrent disease and had the potential in monitoring treatment response.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Qiufang Liu, Si Shi, Shuai Liu, Xiaoping Xu, Silong Hu, Ji Zhang, Chunmei Wang, Xianjun Yu, Shaoli Song
Summary: This study aimed to compare the diagnostic and prognostic performance of [Ga-68]Ga-DOTA-FAPI-04 and [F-18]FDG PET/CT in pancreatic cancer. A total of 51 patients underwent both [Ga-68]Ga-DOTA-FAPI-04 and [F-18]FDG PET/CT. [Ga-68]Ga-DOTA-FAPI-04 showed higher sensitivity than [F-18]FDG in detecting primary tumor, metastatic lymph nodes, and distant metastases. [Ga-68]Ga-DOTA-FAPI-04 also had a higher tumor-to-liver background ratio for liver metastases and was an independent prognostic factor for progression-free survival in pancreatic cancer patients.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiuling Shen, Xin Zhou, Yuan Yao, Xiangxi Meng, Yufei Song, Zhi Yang, Nan Li
Summary: The purpose of this study was to compare the abilities of [Ga-68]Ga-DOTA-FAPI-04 PET/CT and [F-18]FDG PET/CT to stratify the malignancy and invasiveness of thymic epithelial tumours (TETs). Clinical characteristics, CT features, and metabolic parameters of subjects with different pathological types and stages were compared. The results showed that [Ga-68]Ga-DOTA-FAPI-04 PET/CT was superior to [F-18]FDG PET/CT in differentiating thymomas from thymic carcinomas (TCs).
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Liming Chen, Xiaolin Zhong, Limin Li, Xue Li, Ya Liu, Chunmei Guo, Yue Chen, Zhanwen Huang
Summary: The efficacy of [Ga-68]Ga-FAPI-04 PET/CT in identifying lesions and assessing the progression of Crohn's disease (CD) was evaluated, and the technique was found to be highly sensitive in detecting different classes of lesions in all intestinal segments.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Tingting Xu, Haoyuan Ding, Hongjian Ban, Yan Zhu, Yue Chen
Summary: Our case demonstrated that Ga-68-DOTA-FAPI-04 is not superior to F-18-FDG in the imaging of cardiac angiosarcoma, but it is still possible to produce beneficial value in the evaluation of the involvement of the lesion.
CLINICAL NUCLEAR MEDICINE
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Tingting Xu, Yilin Huang, Yan Zhao, Peng Wang, Yue Chen
Summary: This case report describes a patient with synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome. Ga-68-DOTA-FAPI-04 imaging showed increased tracer uptake, which was helpful in evaluating the involved sites of SAPHO syndrome.
CLINICAL NUCLEAR MEDICINE
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Wei Liu, Xiao Yang, Liming Chen, Yue Chen, Tingting Xu
Summary: A 28-year-old woman presented with a 2-month history of chest wall swelling and pain. Chest CT revealed an irregular soft tissue mass in the chest wall and mediastinum. F-18-FDG PET/CT showed significant FDG uptake in the mass. Subsequently, the patient participated in a Ga-68-DOTA-FAPI-04 PET/CT tumor clinical trial, which also showed elevated tracer uptake in the mass. Biopsy confirmed a diagnosis of myeloid sarcoma.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Liang Zhao, Yizhen Pang, Zuoming Luo, Kaili Fu, Tingting Yang, Long Zhao, Long Sun, Hua Wu, Qin Lin, Haojun Chen
Summary: This study aimed to explore the efficacy of [Ga-68]Ga-DOTA-FAPI-04 PET/CT compared to F-18-FDG PET/CT in evaluating peritoneal carcinomatosis in cancer patients. The results showed that [Ga-68]Ga-DOTA-FAPI-04 PET/CT had higher sensitivity, particularly in patients with gastric cancer, and provided better detection of peritoneal lesions compared to F-18-FDG PET/CT.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Min Zhang, Weiwei Quan, Tianqi Zhu, Shuo Feng, Xinyun Huang, Hongping Meng, Run Du, Zhengbin Zhu, Xuezheng Qu, Ping Li, Yuke Cui, Kuangyu Shi, Xiaoxiang Yan, Ruiyan Zhang, Biao Li
Summary: This study evaluated the predictive value of [Ga-68]Ga-DOTA-FAPI-04 PET/MR for late left ventricular remodeling in patients with ST-segment elevated myocardial infarction (STEMI). The results showed that the uptake volume of [Ga-68]Ga-DOTA-FAPI-04 at baseline can predict left ventricular remodeling at 12 months after STEMI. Compared to clinical information and other imaging parameters, [Ga-68]Ga-DOTA-FAPI-04 uptake volume demonstrated better predictive ability.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Annan Zhang, Xiangxi Meng, Yuan Yao, Xin Zhou, Yan Zhang, Nan Li
Summary: This study compared the application of [Ga-68]Ga-DOTA-FAPI-04 and [F-18]FDG PET/CT in fibro-blastic tumors. The results showed that [Ga-68]Ga-DOTA-FAPI-04 outperformed [F-18]FDG PET/CT in displaying the primary, recurrent and metastatic lesions.
EUROPEAN JOURNAL OF RADIOLOGY
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Yi Tao, Feifei Wang, Liming Chen, Zhanwen Huang
Summary: This article reports the PET/CT findings of a 60-year-old woman with breast lymphoma, revealing intense tracer uptake in the breast mass. Biopsy and immunohistochemical examinations confirmed the diagnosis of diffuse large B-cell lymphoma.
CLINICAL NUCLEAR MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Halil Komek, Canan Can, Ihsan Kaplan, Cihan Gundogan, Ferat Kepenek, Huseyin Karaoglan, Aykut Demirkiran, Senar Ebinc, Yunus Guzel, Ebubekir Gundes
Summary: [(68) Ga]Ga-DOTA-FAPI-04 PET/CT demonstrates higher sensitivity and specificity in the evaluation of primary lesions and metastases in patients with colorectal cancer.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Xiuling Shen, Zhi Yang, Nan Li
Summary: We present a case of thoracic SMARCA4-UT, a rare malignant disease, in a 56-year-old woman. Ga-68-DOTA-FAPI-04 PET/CT imaging showed intense uptake in the primary tumor and lymph node metastases, providing valuable insights into the diagnosis and monitoring of treatment response.
CLINICAL NUCLEAR MEDICINE
(2023)
