Covalent inhibitors of GAPDH: From unspecific warheads to selective compounds

Covalent Inhibitors of Plasmodium falciparum Glyceraldehyde 3-Phosphate Dehydrogenase with Antimalarial Activity in Vitro

(2019) Gregorio Cullia et al.   ACS Medicinal Chemistry Letters

Covalent Inhibition in Drug Discovery

(2019) Avick Kumar Ghosh et al.   ChemMedChem

Structural analysis of glyceraldehyde-3-phosphate dehydrogenase functional diversity

(2014) Michael A. Sirover   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Drug discovery considerations in the development of covalent inhibitors

(2013) Robert Mah et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Transglutaminase 2-dependent Deamidation of Glyceraldehyde-3-phosphate Dehydrogenase Promotes Trophoblastic Cell Fusion

(2013) Kaori Iwai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The resurgence of covalent drugs

(2011) Juswinder Singh et al.   NATURE REVIEWS DRUG DISCOVERY

Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor

(2010) Douglas S. Johnson et al.   ACS Medicinal Chemistry Letters

Covalent Modifiers: An Orthogonal Approach to Drug Design

(2009) Michele H. Potashman et al.   JOURNAL OF MEDICINAL CHEMISTRY

Beyond Picomolar Affinities: Quantitative Aspects of Noncovalent and Covalent Binding of Drugs to Proteins

(2008) Adam J. T. Smith et al.   JOURNAL OF MEDICINAL CHEMISTRY