Synthesis of biphenyl oxazole derivatives via Suzuki coupling and biological evaluations as nucleotide pyrophosphatase/phosphodiesterase-1 and -3 inhibitors

Synthesis, biological evaluation, and docking studies of new pyrazole-based thiourea and sulfonamide derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase

(2020) Saif Ullah et al.   BIOORGANIC CHEMISTRY

Synthesis, biological evaluation, and docking studies of new raloxifene sulfonate or sulfamate derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase

(2019) Mohammed I. El-Gamal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Modification of Bischler-Möhlau indole derivatives through palladium catalyzed Suzuki reaction as effective cholinesterase inhibitors, their kinetic and molecular docking studies

(2018) Shaista Parveen et al.   BIOORGANIC CHEMISTRY

Exploration of carboxy pyrazole derivatives: Synthesis, alkaline phosphatase, nucleotide pyrophosphatase/phosphodiesterase and nucleoside triphosphate diphosphohydrolase inhibition studies with potential anticancer profile

(2018) Pervaiz Ali Channar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent advance in oxazole-based medicinal chemistry

(2018) Hui-Zhen Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structural basis for nucleotide recognition by the ectoenzyme CD203c

(2018) Alexei Gorelik et al.   FEBS Journal

Linezolid: a review of its properties, function, and use in critical care

(2018) Seyed MohammadReza Hashemian et al.   Drug Design Development and Therapy

Nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) and its inhibitors

(2017) Sang-Yong Lee et al.   MedChemComm

Flow-assisted basophil activation tests in immediate drug hypersensitivity: two decades of Antwerp experience

(2016) E. A. Mangodt et al.   ACTA CLINICA BELGICA

N-Acylated Derivatives of Sulfamethoxazole and Sulfafurazole Inhibit Intracellular Growth of Chlamydia trachomatis

(2014) S. Marwaha et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Stem cell characteristics in glioblastoma are maintained by the ecto-nucleotidase E-NPP1

(2014) J Bageritz et al.   CELL DEATH AND DIFFERENTIATION

Highly Potent and Selective Ectonucleotide Pyrophosphatase/Phosphodiesterase I Inhibitors Based on an Adenosine 5′-(α or γ)-Thio-(α,β- or β,γ)-methylenetriphosphate Scaffold

(2014) Yael Nadel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Imidazopyridine- and Purine-Thioacetamide Derivatives: Potent Inhibitors of Nucleotide Pyrophosphatase/Phosphodiesterase 1 (NPP1)

(2014) Lei Chang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Identification of Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) as a Regulator ofN-Acetylglucosaminyltransferase GnT-IX (GnT-Vb)

(2013) Hiroaki Korekane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nonhydrolyzable ATP Analogues as Selective Inhibitors of Human NPP1: A Combined Computational/Experimental Study

(2013) Joanna Lecka et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of oxazole-based PDE4 inhibitors with picomolar potency

(2012) Rongze Kuang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

New insights into NPP1 function: Lessons from clinical and animal studies

(2012) N.C.W. Mackenzie et al.   BONE

ATP acts as a survival signal and prevents the mineralization of aortic valve

(2012) Nancy Côté et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling

(2012) K. Kato et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular function and molecular structure of ecto-nucleotidases

(2012) Herbert Zimmermann et al.   Purinergic Signalling

A Silver-Mediated One-Step Synthesis of Oxazoles

(2011) Dougal J. Ritson et al.   JOURNAL OF ORGANIC CHEMISTRY

The expression of ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP1) is correlated with astrocytic tumor grade

(2010) Indra Aerts et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Diadenosine 5′,5′′-(Boranated)polyphosphonate Analogues as Selective Nucleotide Pyrophosphatase/Phosphodiesterase Inhibitors⊥

(2010) Shay Eliahu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Differential expression of nucleotide pyrophosphatase/phosphodiesterases by Walker 256 mammary cancer cells in solid tumors and malignant ascites

(2010) Andréia Buffon et al.   LIFE SCIENCES

Thiazole and Oxazole Alkaloids: Isolation and Synthesis

(2010) Danilo Davyt et al.   Marine Drugs

Calcium deposition in osteoarthritic meniscus and meniscal cell culture

(2010) Yubo Sun et al.   ARTHRITIS RESEARCH & THERAPY

1,3,4-Oxadiazole-2(3H)-thione and its analogues: A new class of non-competitive nucleotide pyrophosphatases/phosphodiesterases 1 inhibitors

(2009) Khalid M. Khan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Quinazolin-4-piperidin-4-methyl sulfamide PC-1 inhibitors: Alleviating hERG interactions through structure based design

(2009) Snahel D. Patel et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Role of Membrane Glycoprotein Plasma Cell Antigen 1/Ectonucleotide Pyrophosphatase Phosphodiesterase 1 in the Pathogenesis of Insulin Resistance and Related Abnormalities

(2008) Ira D. Goldfine et al.   ENDOCRINE REVIEWS