Single-molecule RNA detection at depth by hybridization chain reaction and tissue hydrogel embedding and clearing

Multiplexed Intact-Tissue Transcriptional Analysis at Cellular Resolution

(2016) Emily Lauren Sylwestrak et al.   CELL

Automated detection and quantification of single RNAs at cellular resolution in zebrafish embryos

(2015) L. Carine Stapel et al.   DEVELOPMENT

Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping

(2015) Jennifer B Treweek et al.   Nature Protocols

Whole-mount single molecule FISH method for zebrafish embryo

(2015) Yuma Oka et al.   Scientific Reports

Next-Generation in Situ Hybridization Chain Reaction: Higher Gain, Lower Cost, Greater Durability

(2014) Harry M. T. Choi et al.   ACS Nano

In This Issue

(2014)   CELL

Single-cell in situ RNA profiling by sequential hybridization

(2014) Eric Lubeck et al.   NATURE METHODS

Advanced CLARITY for rapid and high-resolution imaging of intact tissues

(2014) Raju Tomer et al.   Nature Protocols

Structural and molecular interrogation of intact biological systems

(2013) Kwanghun Chung et al.   NATURE

Single-cell systems biology by super-resolution imaging and combinatorial labeling

(2012) Eric Lubeck et al.   NATURE METHODS

Scanned light sheet microscopy with confocal slit detection

(2012) Eugen Baumgart et al.   OPTICS EXPRESS

Programmable in situ amplification for multiplexed imaging of mRNA expression

(2010) Harry M T Choi et al.   NATURE BIOTECHNOLOGY

Fast, high-contrast imaging of animal development with scanned light sheet–based structured-illumination microscopy

(2010) Philipp J Keller et al.   NATURE METHODS

Imaging individual mRNA molecules using multiple singly labeled probes

(2008) Arjun Raj et al.   NATURE METHODS