DrosophilaCrumbs prevents ectopic Notch activation in developing wings by inhibiting ligand-independent endocytosis

Dynamics of epithelial cell polarity in Drosophila: how to regulate the regulators?

(2016) David Flores-Benitez et al.   CURRENT OPINION IN CELL BIOLOGY

Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap

(2015) Aleksander D. Szymaniak et al.   DEVELOPMENTAL CELL

Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular organs

(2015) Alejo E. Rodríguez-Fraticelli et al.   NATURE CELL BIOLOGY

Ligand-Independent Mechanisms of Notch Activity

(2015) William Hunt Palmer et al.   TRENDS IN CELL BIOLOGY

Mouse Crumbs3 sustains epithelial tissue morphogenesis in vivo

(2015) Lucie E. Charrier et al.   Scientific Reports

Organization and execution of the epithelial polarity programme

(2014) Enrique Rodriguez-Boulan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Crumbs promotes expanded recognition and degradation by the SCFSlimb/ -TrCP ubiquitin ligase

(2014) P. Ribeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cis-interactions between Notch and its ligands block ligand-independent Notch activity

(2014) William Hunt Palmer et al.   eLife

Sanpodo controls sensory organ precursor fate by directing Notch trafficking and binding γ-secretase

(2013) Alok Upadhyay et al.   JOURNAL OF CELL BIOLOGY

A functional role of the extracellular domain of Crumbs in cell architecture and apicobasal polarity

(2013) A. Letizia et al.   JOURNAL OF CELL SCIENCE

CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion

(2013) H. J. k. Balderhaar et al.   JOURNAL OF CELL SCIENCE

Crumbs3 Is Essential for Proper Epithelial Development and Viability

(2013) E. L. Whiteman et al.   MOLECULAR AND CELLULAR BIOLOGY

Fosmid-Based Structure-Function Analysis Reveals Functionally Distinct Domains in the Cytoplasmic Domain of Drosophila Crumbs

(2013) Sven Klose et al.   G3-Genes Genomes Genetics

Positive Feedback and Mutual Antagonism Combine to Polarize Crumbs in the Drosophila Follicle Cell Epithelium

(2012) Georgina C. Fletcher et al.   CURRENT BIOLOGY

Differences in levels of the transmembrane protein Crumbs can influence cell survival at clonal boundaries

(2012) Yassi Hafezi et al.   DEVELOPMENTAL BIOLOGY

Crb Apical Polarity Proteins Maintain Zebrafish Retinal Cone Mosaics via Intercellular Binding of Their Extracellular Domains

(2012) Jian Zou et al.   DEVELOPMENTAL CELL

Drosophilamidgut homeostasis involves neutral competition between symmetrically dividing intestinal stem cells

(2012) Joaquín de Navascués et al.   EMBO JOURNAL

Crumbs limits oxidase-dependent signaling to maintain epithelial integrity and prevent photoreceptor cell death

(2012) François J.-M. Chartier et al.   JOURNAL OF CELL BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

The Notch signalling system: recent insights into the complexity of a conserved pathway

(2012) K. G. Guruharsha et al.   NATURE REVIEWS GENETICS

Endocytic routes to Notch activation

(2012) Martin Baron   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Notch Signaling

(2012) R. Kopan   Cold Spring Harbor Perspectives in Biology

The Apical Polarity Protein Network in Drosophila Epithelial Cells: Regulation of Polarity, Junctions, Morphogenesis, Cell Growth, and Survival

(2011) Ulrich Tepass   Annual Review of Cell and Developmental Biology

Notch signaling: simplicity in design, versatility in function

(2011) E. R. Andersson et al.   DEVELOPMENT

Deficiency in crumbs homolog 2 (Crb2) affects gastrulation and results in embryonic lethality in mice

(2011) Zhijie Xiao et al.   DEVELOPMENTAL DYNAMICS

Roles of Drosophila Deltex in Notch receptor endocytic trafficking and activation

(2011) Kenta Yamada et al.   GENES TO CELLS

Notch signaling and Notch signaling modifiers

(2011) Michael M. Wang   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Emerging Role for Epithelial Polarity Proteins of the Crumbs Family as Potential Tumor Suppressors

(2011) Patrick Laprise   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal

(2011) Kazuya Hori et al.   JOURNAL OF CELL BIOLOGY

Dual Roles of Notch in Regulation of Apically Restricted Mitosis and Apicobasal Polarity of Neuroepithelial Cells

(2011) Shinya Ohata et al.   NEURON

Translational Pausing Ensures Membrane Targeting and Cytoplasmic Splicing of XBP1u mRNA

(2011) K. Yanagitani et al.   SCIENCE

The cell giveth and the cell taketh away: An overview of Notch pathway activation by endocytic trafficking of ligands and receptors

(2010) Emily B. Pratt et al.   ACTA HISTOCHEMICA

Crumbs is required to achieve proper organ size control during Drosophila head development

(2010) E. C. N. Richardson et al.   DEVELOPMENT

Cis-interactions between Notch and Delta generate mutually exclusive signalling states

(2010) David Sprinzak et al.   NATURE

The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded

(2010) C. Ling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila

(2010) C.-L. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Sanpodo: a context-dependent activator and inhibitor of Notch signaling during asymmetric divisions

(2009) A. B. Babaoglan et al.   DEVELOPMENT

The Crumbs complex: from epithelial-cell polarity to retinal degeneration

(2009) N. A. Bulgakova et al.   JOURNAL OF CELL SCIENCE

Role of the Polarity Determinant Crumbs in Suppressing Mammalian Epithelial Tumor Progression

(2008) C. M. Karp et al.   CANCER RESEARCH

Drosophila HOPS and AP-3 Complex Genes Are Required for a Deltex-Regulated Activation of Notch in the Endosomal Trafficking Pathway

(2008) Marian Wilkin et al.   DEVELOPMENTAL CELL