Gestational stress induces the unfolded protein response, resulting in heart defects

Effect of maternal diabetes on the embryo, fetus, and children: Congenital anomalies, genetic and epigenetic changes and developmental outcomes

(2015) Asher Ornoy et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Risk of Congenital Heart Defects in the Offspring of Smoking Mothers: A Population-Based Study

(2015) Patrick M. Sullivan et al.   JOURNAL OF PEDIATRICS

Maternal Hypertension During Pregnancy and the Risk of Congenital Heart Defects in Offspring: A Systematic Review and Meta-analysis

(2015) Anushuya Ramakrishnan et al.   PEDIATRIC CARDIOLOGY

Therapeutic Drugs that Slow the Heart Rate of Early Rat Embryos. Is there a Risk for the Human?

(2014) William Webster et al.   CURRENT PHARMACEUTICAL DESIGN

Gene–environment interaction demonstrates the vulnerability of the embryonic heart

(2014) Victoria C. O׳Reilly et al.   DEVELOPMENTAL BIOLOGY

Cited2 is required in trophoblasts for correct placental capillary patterning

(2014) Julie L.M. Moreau et al.   DEVELOPMENTAL BIOLOGY

Nucleolar stress with and without p53

(2014) Allison James et al.   Nucleus

Prevalence of Symptomatic Congenital Heart Disease in Tibetan School Children

(2013) Jian-Yong Zheng et al.   AMERICAN JOURNAL OF CARDIOLOGY

Of mice and men: molecular genetics of congenital heart disease

(2013) Troels Askhøj Andersen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Genetics of Congenital Heart Disease

(2013) Akl C. Fahed et al.   CIRCULATION RESEARCH

Two phases of disulfide bond formation have differing requirements for oxygen

(2013) Marianne Koritzinsky et al.   JOURNAL OF CELL BIOLOGY

Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice

(2013) J. A. Moreno et al.   Science Translational Medicine

The unfolded protein response triggered by environmental factors

(2013) Masanori Kitamura   Seminars in Immunopathology

Cardiac outflow tract anomalies

(2013) Zachary Neeb et al.   Wiley Interdisciplinary Reviews-Developmental Biology

A Mechanism for Gene-Environment Interaction in the Etiology of Congenital Scoliosis

(2012) Duncan B. Sparrow et al.   CELL

Comparative functional analysis of two fibroblast growth factor receptor 1 (FGFR1) mutations affecting the same residue (R254W and R254Q) in isolated hypogonadotropic hypogonadism (IHH)

(2012) Vasiliki Koika et al.   GENE

Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)

(2012) Jeffrey M. Axten et al.   JOURNAL OF MEDICINAL CHEMISTRY

Congenital heart disease: current knowledge about causes and inheritance

(2012) Gillian M Blue et al.   MEDICAL JOURNAL OF AUSTRALIA

The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

(2012) B. C. S. Cross et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organogenesis of the vertebrate heart

(2012) Lucile Miquerol et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Endoplasmic reticulum stress in maternal diabetes-induced cardiac malformations during critical cardiogenesis period

(2011) Zhiyong Zhao   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease

(2011) N. Itoh et al.   JOURNAL OF BIOCHEMISTRY

Birth Prevalence of Congenital Heart Disease Worldwide

(2011) Denise van der Linde et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

FGF signalling: diverse roles during early vertebrate embryogenesis

(2010) K. Dorey et al.   DEVELOPMENT

The Nucleolus under Stress

(2010) Séverine Boulon et al.   MOLECULAR CELL

Role of Mesodermal FGF8 and FGF10 Overlaps in the Development of the Arterial Pole of the Heart and Pharyngeal Arch Arteries

(2009) Yusuke Watanabe et al.   CIRCULATION RESEARCH

The Role of Hypoxia in Development of the Mammalian Embryo

(2009) Sally L. Dunwoodie   DEVELOPMENTAL CELL

Frs2 -deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis

(2008) J. Zhang et al.   DEVELOPMENT

An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart

(2008) E. J. Park et al.   DEVELOPMENT

Identification of downstream genetic pathways of Tbx1 in the second heart field

(2008) Jun Liao et al.   DEVELOPMENTAL BIOLOGY

The developmental genetics of congenital heart disease

(2008) Benoit G. Bruneau   NATURE